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Title:          Migrated T lymphocytes into malignant pleural effusions: an indicator of good prognosis in lung adenocarcinoma patients
Subject:        Scientific Reports, doi:10.1038/s41598-018-35840-3
Keywords:       
Author:         Juan C. Nieto
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     Item: 
      Title: Migrated T lymphocytes into malignant pleural effusions: an indicator of good prognosis in lung adenocarcinoma patients
      Children: 
       Item: 
        Title: Material and Methods
        Children: 
         Item: 
          Title: Patients and sample collection. 
         Item: 
          Title: Staining and flow cytometry analysis of pleural fluid cells. 
         Item: 
          Title: Migration assay to malignant pleural fluid and analysis of migrated peripheral blood lymphocytes from healthy donors. 
         Item: 
          Title: Proliferation assay of T cells from pleural effusions. 
         Item: 
          Title: Determination of cytokine and chemokine concentrations in MPEs. 
         Item: 
          Title: Statistical analysis. 
         Item: 
          Title: Ethical approval. 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Cellular composition of malignant and non-malignant pleural effusions. 
         Item: 
          Title: Relationship between lymphocytes and tumor cells in malignant pleural effusions from lung adenocarcinoma. 
         Item: 
          Title: Migration of lymphocytes to malignant pleural fluids and its association with CXCL10 concentration. 
         Item: 
          Title: Levels of T-related cytokines in pleural fluids and their relationships with T lymphocyte populations. 
         Item: 
          Title: Association between leukocytes and cytokine levels in MPE and survival after MPE diagnosis. 
       Item: 
        Title: Discussion
        Children: 
         Item: 
          Title: Compliance with Ethical Standards. 
       Item: 
        Title: Acknowledgements
       Item: 
        Title: Figure 1 Leukocytes and lymphocyte subpopulations in malignant and non-malignant pleural effusions.
       Item: 
        Title: Figure 2 Correlation between lymphocyte populations and tumor cells in malignant pleural effusions from lung cancer.
       Item: 
        Title: Figure 3 Association between migration of lymphocytes toward malignant pleural fluids and number of lymphocytes in malignant pleural effusions.
       Item: 
        Title: Figure 4 IL-10, IFNγ and IL-17 levels in MPE from LAC and pleural fluids from HF and the relationship of cytokines with T CD4+ lymphocytes per ml in MPE.
       Item: 
        Title: Figure 5 Association of cytokines and leukocytes per ml in MPE with survival days from MPE formation.
       Item: 
        Title: Table 1 Clinical characteristics of LAC and HF patients, and relative leukocyte composition of their pleural fluids.
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                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. 
Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. 
</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. 
Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. 

Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” 
</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. 
The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. 
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
                  <pdfaSchema:property>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
                           <pdfaProperty:name>journal_article_version</pdfaProperty:name>
                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
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