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FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: The LOX Family of ECM-Modifying Enzymes Destination: section.2 Item: Title: LOX Isoenzymes in the Cardiovascular System Destination: section.3 Item: Title: ECM Synthesis and Remodeling in the Heart Destination: section.4 Children: Item: Title: LOX and LOXLs in Dilated and Hypertrophic Cardiomyopathies and HF Destination: subsection.4.1 Item: Title: LOX/LOXLs in Post-MI Cardiac Remodeling Destination: subsection.4.2 Item: Title: LOX Activity in Cardiac Remodeling and Fibrosis Associated With Obesity and Metabolic Syndrome Destination: subsection.4.3 Item: Title: LOX and LOXL2 in Atrial Fibrillation Destination: subsection.4.4 Item: Title: LOX in Other Pathophysiological Settings Leading to Cardiac Dysfunction Destination: subsection.4.5 Item: Title: LOX/LOXLs as Pharmacological Targets in Myocardial Diseases Destination: section.5 Item: Title: Conclusions and Therapeutic Opportunities Destination: section.6 Item: Title: References Destination: section.6 Info: Producer: iText® 7.1.1 ©2000-2018 iText Group NV (AGPL-version) CreationDate: Sat Dec 14 09:17:23 CET 2019 ModDate: Sat Dec 14 09:17:23 CET 2019 ID: 0x40c4acdf57ec850067fd597e7ee131ef, 0x40c4acdf57ec850067fd597e7ee131ef Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: IOJCNK+VnURWPalladioL-Bold FontSubset: true FirstChar: 161 LastChar: 189 FontDescriptor: FontName: IOJCNK+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VSHNAE+Rpcxr FontSubset: true FirstChar: 169 LastChar: 169 FontDescriptor: FontName: VSHNAE+Rpcxr Flags: Symbolic FontBBox: -212, -286, 1344, 973 FontFile: true Font: BaseFont: MDECKF+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 122 FontDescriptor: FontName: MDECKF+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, 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