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Introduction Destination: flink1 Item: Title: 2. Methods Destination: flink2 Children: Item: Title: 2.1. Participants: EMIF-AD Multimodal Biomarker Discovery study Destination: slink1 Item: Title: 2.2. SOMAscan assay Destination: slink2 Item: Title: 2.3. Statistical analysis Destination: slink3 Item: Title: 2.4. Machine learning Destination: slink4 Item: Title: 2.5. Mendelian randomization Destination: slink5 Item: Title: 3. Results Destination: flink3 Children: Item: Title: 3.1. Subject demographics Destination: slink6 Item: Title: 3.2. Proteins significantly associated with amyloid Z-score in both groups Destination: slink7 Item: Title: 3.3. Multiprotein classifier of amyloid normal/abnormal status and other AD endophenotypes Destination: slink8 Item: Title: 3.4. Causal relationship between amyloid and tau pathology Destination: slink9 Item: Title: 4. 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Link Rect: 317, 108, 539, 116 Annotation: Subtype: Link Rect: 317, 98, 440, 106 Annotation: Subtype: Link Rect: 317, 88, 539, 96 Annotation: Subtype: Link Rect: 317, 78, 539, 86 Annotation: Subtype: Link Rect: 317, 68, 495, 76 Annotation: Subtype: Link Rect: 317, 58, 539, 66 Annotation: Subtype: Link Rect: 317, 48, 539, 56 Annotation: Subtype: Link Rect: 317, 38, 484, 46 Page: Label: 1488 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 54, 696, 276, 704 Annotation: Subtype: Link Rect: 54, 686, 276, 694 Annotation: Subtype: Link Rect: 54, 676, 276, 684 Annotation: Subtype: Link Rect: 54, 666, 276, 674 Annotation: Subtype: Link Rect: 54, 656, 138, 664 Annotation: Subtype: Link Rect: 54, 646, 276, 654 Annotation: Subtype: Link Rect: 54, 636, 276, 644 Annotation: Subtype: Link Rect: 54, 626, 276, 634 Annotation: Subtype: Link Rect: 54, 616, 100, 624 Annotation: Subtype: Link Rect: 54, 606, 276, 614 Annotation: Subtype: Link Rect: 54, 596, 276, 604 Annotation: Subtype: Link Rect: 54, 586, 276, 594 Annotation: Subtype: Link Rect: 54, 576, 110, 584 Annotation: Subtype: Link Rect: 54, 566, 276, 574 Annotation: Subtype: Link Rect: 54, 556, 276, 564 Annotation: Subtype: Link Rect: 54, 546, 276, 554 Annotation: Subtype: Link Rect: 54, 536, 134, 544 Annotation: Subtype: Link Rect: 54, 526, 276, 534 Annotation: Subtype: Link Rect: 54, 516, 276, 524 Annotation: Subtype: Link Rect: 54, 506, 255, 514 Annotation: Subtype: Link Rect: 54, 496, 276, 504 Annotation: Subtype: Link Rect: 54, 486, 276, 494 Annotation: Subtype: Link Rect: 54, 476, 92, 484 Annotation: Subtype: Link Rect: 54, 466, 276, 474 Annotation: Subtype: Link Rect: 54, 457, 276, 464 Annotation: Subtype: Link Rect: 54, 447, 274, 455 Annotation: Subtype: Link Rect: 54, 437, 276, 445 Annotation: Subtype: Link Rect: 54, 427, 92, 435 Annotation: Subtype: Link Rect: 54, 417, 276, 425 Annotation: Subtype: Link Rect: 54, 407, 276, 415 Annotation: Subtype: Link Rect: 54, 397, 276, 405 Annotation: Subtype: Link Rect: 54, 387, 276, 395 Annotation: Subtype: Link Rect: 54, 377, 139, 385 Annotation: Subtype: Link Rect: 54, 367, 276, 375 Annotation: Subtype: Link Rect: 54, 357, 276, 365 Annotation: Subtype: Link Rect: 317, 696, 539, 704 Annotation: Subtype: Link Rect: 317, 686, 373, 694 Annotation: Subtype: Link Rect: 317, 676, 539, 684 Annotation: Subtype: Link Rect: 317, 666, 539, 674 Annotation: Subtype: Link Rect: 317, 656, 539, 664 Annotation: Subtype: Link Rect: 317, 646, 355, 654 Annotation: Subtype: Link Rect: 317, 636, 539, 644 Annotation: Subtype: Link Rect: 317, 626, 539, 634 Annotation: Subtype: Link Rect: 317, 616, 539, 624 Annotation: Subtype: Link Rect: 317, 606, 349, 614 Annotation: Subtype: Link Rect: 317, 596, 539, 604 Annotation: Subtype: Link Rect: 317, 586, 539, 594 Annotation: Subtype: Link Rect: 317, 576, 359, 584 Annotation: Subtype: Link Rect: 317, 566, 539, 574 Annotation: Subtype: Link Rect: 317, 556, 539, 564 Annotation: Subtype: Link Rect: 317, 546, 347, 554 Annotation: Subtype: Link Rect: 317, 536, 539, 544 Annotation: Subtype: Link Rect: 317, 526, 539, 534 Annotation: Subtype: Link Rect: 317, 516, 539, 524 Annotation: Subtype: Link Rect: 317, 506, 373, 514 Annotation: Subtype: Link Rect: 317, 496, 539, 504 Annotation: Subtype: Link Rect: 317, 486, 539, 494 Annotation: Subtype: Link Rect: 317, 476, 539, 484 Annotation: Subtype: Link Rect: 317, 466, 467, 474 Annotation: Subtype: Link Rect: 317, 457, 539, 464 Annotation: Subtype: Link Rect: 317, 447, 539, 455 Annotation: Subtype: Link Rect: 317, 437, 539, 445 Annotation: Subtype: Link Rect: 317, 427, 398, 435 Annotation: Subtype: Link Rect: 317, 417, 539, 425 Annotation: Subtype: Link Rect: 317, 407, 539, 415 Annotation: Subtype: Link Rect: 317, 397, 539, 405 Annotation: Subtype: Link Rect: 317, 387, 367, 395 Annotation: Subtype: Link Rect: 317, 377, 539, 385 Annotation: Subtype: Link Rect: 317, 367, 539, 375 Annotation: Subtype: Link Rect: 317, 357, 498, 365 Checksum: 332ecaf9 Type: CRC32 Checksum: 8219884e4e97fcc6403b91305ebf5828 Type: MD5 Checksum: a81e8ae75dc1be7ceeed37537a6f235dc84c6809 Type: SHA-1 Checksum: 4d7d206e361e8b28e2bb164339cc10947381b19ac3457da5f8f964c05827a463 Type: SHA-256