9f52f9d5e53fec96aa76fcdc3c71970c  286448.pdf
52d42b29d91bb23f435beb92fbdd23accc7b16d4  286448.pdf
dd224b793ee32250794f1c9fc3a41be921a12eba3a4c20729ba12fc488be2e75  286448.pdf

Title:          Generation of an integration-free iPSC line, ICCSICi005-A, derived from a Parkinson's disease patient carrying the L444P mutation in the GBA1 gene
Subject:        Stem Cell Research, 40 (2020) 101578. doi:10.1016/j.scr.2019.101578
Keywords:       
Author:         Eva Rodríguez-Traver
Creator:        Elsevier
CreationDate:   Mon Feb  3 15:44:33 2020 CET
ModDate:        Mon Feb  3 15:44:33 2020 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           AcroForm
JavaScript:     no
Pages:          5
Encrypted:      no
Page size:      595.276 x 793.701 pts
Page rot:       0
File size:      1095498 bytes
Optimized:      yes
PDF version:    1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
FAOQAD+CharisSIL                     CID Type 0C       Identity-H       yes yes yes    280  0
DUDUKS+CharisSIL                     Type 1C           Custom           yes yes yes    257  0
IZGLKW+UniversLTStd                  Type 1C           Custom           yes yes yes    258  0
TAUMQQ+CharisSIL-Italic              Type 1C           Custom           yes yes yes    259  0
IMHHKY+STIXGeneral-Regular           Type 1C           Custom           yes yes yes    270  0
HKBIXM+CharisSIL-Bold                Type 1C           Custom           yes yes yes    272  0
FAOQAD+CharisSIL-Italic              CID Type 0C       Identity-H       yes yes yes     81  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2023-12-21 02:34:54 CET
 RepresentationInformation: 286448.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2023-12-20 11:25:53 CET
  Size: 1095498
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 336
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: en
    Outlines: 
     Item: 
      Title: Generation of an integration-free iPSC line, ICCSICi005-A, derived from a Parkinson's disease patient carrying the L444P mutation in the GBA1 gene
      Destination: mk:title
      Children: 
       Item: 
        Title: Resource utility
        Destination: mk:H1_1
        Children: 
         Item: 
          Title: Resource details
          Destination: mk:H2_2
       Item: 
        Title: Materials and methods
        Destination: mk:H1_3
        Children: 
         Item: 
          Title: Reprogramming of dermal fibroblasts
          Destination: mk:H2_4
         Item: 
          Title: Embryoid body (EB) formation and three-lineage differentiation
          Destination: mk:H2_5
         Item: 
          Title: Immunocytochemistry
          Destination: mk:H2_6
         Item: 
          Title: RT-qPCR
          Destination: mk:H2_7
         Item: 
          Title: Sendai virus and transgene detection
          Destination: mk:H2_8
         Item: 
          Title: Karyotyping
          Destination: mk:H2_9
         Item: 
          Title: Genotyping
          Destination: mk:H2_10
         Item: 
          Title: Mycoplasma detection
          Destination: mk:H2_11
         Item: 
          Title: Short tandem repeat (STR) analysis
          Destination: mk:H2_12
         Item: 
          Title: Key resource table
          Destination: mk:H2_13
       Item: 
        Title: Acknowledgments
        Destination: mk:H1_15
       Item: 
        Title: mk:H1_16
        Destination: mk:H1_16
       Item: 
        Title: mk:H1_17
        Destination: mk:H1_17
       Item: 
        Title: References
        Destination: mk:H1_18
   Info: 
    Title: Generation of an integration-free iPSC line, ICCSICi005-A, derived from a Parkinson's disease patient carrying the L444P mutation in the GBA1 gene
    Author: Eva Rodríguez-Traver
    Subject: Stem Cell Research, 40 (2020) 101578. doi:10.1016/j.scr.2019.101578
    Keywords: 
    Creator: Elsevier
    CreationDate: Mon Feb 03 15:44:33 CET 2020
    ModDate: Mon Feb 03 15:44:33 CET 2020
   ID: 0x5d0648cedd30e8d3d0b87f3f64770cd6, 0xe4b45382de68a6478a581b4bf6adee57
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 236
      ImageHeight: 298
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 247
      ImageHeight: 271
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2100
      ImageHeight: 2722
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type0: 
     Font: 
      BaseFont: FAOQAD+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: FAOQAD+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: HKBIXM+CharisSIL-Bold
      FontSubset: true
      FirstChar: 1
      LastChar: 32
      FontDescriptor: 
       FontName: HKBIXM+CharisSIL-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -720, -533, 3000, 1270
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DUDUKS+CharisSIL
      FontSubset: true
      FirstChar: 1
      LastChar: 93
      FontDescriptor: 
       FontName: DUDUKS+CharisSIL
       Flags: Nonsymbolic
       FontBBox: -692, -533, 3000, 1270
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IZGLKW+UniversLTStd
      FontSubset: true
      FirstChar: 1
      LastChar: 21
      FontDescriptor: 
       FontName: IZGLKW+UniversLTStd
       Flags: Nonsymbolic
       FontBBox: -168, -250, 992, 947
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: TAUMQQ+CharisSIL-Italic
      FontSubset: true
      FirstChar: 1
      LastChar: 61
      FontDescriptor: 
       FontName: TAUMQQ+CharisSIL-Italic
       Flags: Nonsymbolic, Italic
       FontBBox: -716, -533, 3058, 1270
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IMHHKY+STIXGeneral-Regular
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: IMHHKY+STIXGeneral-Regular
       Flags: Nonsymbolic
       FontBBox: -995, -455, 2000, 1055
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    CIDFontType0: 
     Font: 
      BaseFont: FAOQAD+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: FAOQAD+CharisSIL
       Flags: Serif, Symbolic
       FontBBox: -692, -533, 3000, 1270
       FontFile3: true
     Font: 
      BaseFont: FAOQAD+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: FAOQAD+CharisSIL-Italic
       Flags: Serif, Symbolic, Italic
       FontBBox: -716, -533, 3058, 1270
       FontFile3: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.2-c001 63.139439, 2010/09/27-13:37:26        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1016/j.scr.2019.101578</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Generation of an integration-free iPSC line, ICCSICi005-A, derived from a Parkinson's disease patient carrying the L444P mutation in the GBA1 gene</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Eva Rodríguez-Traver</rdf:li>
               <rdf:li>César Rodríguez</rdf:li>
               <rdf:li>Eva Díaz-Guerra</rdf:li>
               <rdf:li>Fabián Arenas</rdf:li>
               <rdf:li>Marcos Araúzo-Bravo</rdf:li>
               <rdf:li>María Orera</rdf:li>
               <rdf:li>Jaime Kulisevsky</rdf:li>
               <rdf:li>Rosario Moratalla</rdf:li>
               <rdf:li>Carlos Vicario</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Elsevier</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Stem Cell Research, 40 (2020) 101578. doi:10.1016/j.scr.2019.101578</rdf:li>
            </rdf:Alt>
         </dc:description>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Stem Cell Research</prism:publicationName>
         <prism:copyright>© 2019 The Authors. Published by Elsevier B.V.</prism:copyright>
         <prism:issn>1873-5061</prism:issn>
         <prism:volume>40</prism:volume>
         <prism:coverDisplayDate>October 2019</prism:coverDisplayDate>
         <prism:pageRange>101578</prism:pageRange>
         <prism:startingPage>101578</prism:startingPage>
         <prism:doi>10.1016/j.scr.2019.101578</prism:doi>
         <prism:url>https://doi.org/10.1016/j.scr.2019.101578</prism:url>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1016/j.scr.2019.101578</crossmark:DOI>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>elsevier.com</rdf:li>
               <rdf:li>sciencedirect.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <FCi27zd_7z9aOowmGmdyOzsNNz9b.lt7-yMaGyPqLyPiPytn_z9uQo9eQmdmJn92MmtuTma/>
         <pdfx:doi>10.1016/j.scr.2019.101578</pdfx:doi>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>elsevier.com</rdf:li>
               <rdf:li>sciencedirect.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>Elsevier</xmp:CreatorTool>
         <xmp:ModifyDate>2020-02-03T14:44:33Z</xmp:ModifyDate>
         <xmp:CreateDate>2020-02-03T14:44:33Z</xmp:CreateDate>
         <xmp:MetadataDate>2020-02-03T14:44:33Z</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords/>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:f28fb738-462d-44e2-9959-c27483e42236</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:8d32a7ea-af0a-413a-b25d-d1f4215d1da4</xmpMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:ali="http://www.niso.org/schemas/ali/1.0/">
         <ali:license_ref>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <ali:uri>http://creativecommons.org/licenses/BY-NC-ND/4.0/</ali:uri>
               </rdf:li>
            </rdf:Bag>
         </ali:license_ref>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 322, 723, 369, 731
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 280, 668, 399, 676
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 37, 730, 37, 742
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 139, 580, 143, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 146, 580, 150, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 233, 580, 237, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 320, 580, 324, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 326, 580, 331, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 404, 580, 409, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 411, 580, 415, 591
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 138, 567, 142, 578
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 206, 567, 210, 578
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 297, 567, 301, 578
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 303, 567, 308, 578
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 398, 567, 402, 578
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 405, 567, 409, 578
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 103, 554, 107, 565
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 110, 554, 114, 565
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 116, 555, 120, 566
       Flags: Print
       Destination: 217
      Annotation: 
       Subtype: Link
       Rect: 225, 231, 288, 239
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 37, 220, 55, 228
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 61, 220, 148, 228
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 154, 220, 243, 228
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 250, 220, 288, 228
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 37, 210, 140, 218
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 395, 325, 416, 333
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 423, 325, 451, 333
       Flags: Print
       Destination: 4
      Annotation: 
       Subtype: Link
       Rect: 422, 304, 444, 312
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 461, 283, 481, 291
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 445, 272, 467, 280
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 490, 262, 511, 270
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 493, 210, 513, 218
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 527, 210, 554, 218
       Flags: Print
       Destination: 4
      Annotation: 
       Subtype: Link
       Rect: 384, 168, 404, 176
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 37, 75, 176, 82
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 97, 92, 166, 99
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 231, 747, 375, 760
      Annotation: 
       Subtype: Link
       Rect: 499, 605, 536, 623
    Page: 
     Label: 2
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 243, 423, 270, 431
       Flags: Print
       Destination: 4
      Annotation: 
       Subtype: Link
       Rect: 67, 350, 94, 357
       Flags: Print
       Destination: 4
      Annotation: 
       Subtype: Link
       Rect: 352, 370, 449, 378
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 389, 360, 417, 368
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 422, 297, 515, 305
       Flags: Print
       Destination: 51
      Annotation: 
       Subtype: Link
       Rect: 356, 287, 383, 295
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 560, 203, 560, 211
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 306, 193, 333, 201
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 467, 686, 483, 693
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 467, 678, 483, 684
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 467, 660, 483, 667
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 467, 643, 483, 650
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 467, 566, 483, 573
       Flags: Print
       Destination: 1
    Page: 
     Label: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 431, 669, 467, 676
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 431, 661, 467, 667
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 460, 652, 492, 658
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 431, 643, 467, 650
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 431, 635, 467, 641
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 446, 618, 478, 624
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 444, 609, 476, 616
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 432, 601, 464, 607
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 435, 592, 470, 599
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 478, 575, 510, 581
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 478, 567, 510, 573
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 478, 558, 513, 564
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 478, 549, 513, 556
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 510, 541, 545, 547
       Flags: Print
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 203, 656, 264, 663
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 231, 476, 282, 483
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 468, 278, 474
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 459, 272, 466
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 451, 280, 457
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 442, 276, 448
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 433, 258, 440
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 425, 275, 431
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 159, 416, 234, 423
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 529, 726, 557, 734
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 306, 716, 432, 724
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 511, 501, 556, 508
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 493, 376, 500
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 368, 469, 512, 476
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 446, 418, 452
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 534, 422, 556, 428
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 414, 399, 420
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 306, 406, 557, 412
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 398, 557, 404
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 390, 556, 396
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 382, 408, 388
       Flags: Print
  Checksum: 9bfaac51
   Type: CRC32
  Checksum: 9f52f9d5e53fec96aa76fcdc3c71970c
   Type: MD5
  Checksum: 52d42b29d91bb23f435beb92fbdd23accc7b16d4
   Type: SHA-1
  Checksum: dd224b793ee32250794f1c9fc3a41be921a12eba3a4c20729ba12fc488be2e75
   Type: SHA-256