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Valdivielso Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Fri Feb 22 13:56:01 2019 CET ModDate: Fri Feb 22 16:10:03 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 1228991 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- BMZVXK+MinionPro-Regular Type 1 Custom yes yes no 31 0 ITGMII+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 32 0 DECNDR+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 33 0 CCVXXJ+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 38 0 XNILIA+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 39 0 NLTBBQ+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 40 0 UZSBMN+MinionPro-It Type 1 Custom yes yes no 132 0 YEPIPF+MinionPro-Bold Type 1 Custom yes yes no 145 0 LGJNYH+MTSYN Type 1 Builtin yes yes no 148 0 LCLVDP+BLEX Type 1 Custom yes yes no 201 0 MIJYAG+RBLMI Type 1 Builtin yes yes no 202 0 ITOYRU+MTGU Type 1 Builtin yes yes no 204 0 IOOPAA+RMTMIB Type 1 Builtin yes yes no 256 0 WLTEQU+MTGUB Type 1 Builtin yes yes no 257 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2023-12-22 02:34:07 CET RepresentationInformation: 286553.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-12-21 10:38:44 CET Size: 1228991 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 591 FreeObjects: 7 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Study Design and Participants Item: Title: SNP Selection and Genotyping Item: Title: Statistical Analysis Item: Title: Results Children: Item: Title: Heterogeneity Analysis in Case-Control Groups Item: Title: Association of Single SNPs With CKD Item: Title: Association of Combination of SNPs With CKD Item: Title: Discussion Item: Title: Ethics Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Info: Title: Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort Author: Isabel Rodriguez and José M. Valdivielso Subject: Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Keywords: chronic kidney disease, risk factors, genetic association study, single nucleotide polymorphism, linkage disequilibrium, haplotype Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Fri Feb 22 14:26:01 CET 2019 ModDate: Fri Feb 22 16:40:03 CET 2019 ID: 0x3e6091d69974c013c94f4346cfb72c17, 0xf621fe8b243fe84ead84c4617218ed14 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: ITGMII+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 37 LastChar: 124 FontDescriptor: FontName: ITGMII+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: IOOPAA+RMTMIB FontSubset: true FirstChar: 95 LastChar: 95 FontDescriptor: FontName: IOOPAA+RMTMIB Flags: Symbolic FontBBox: 0, -250, 994, 706 FontFile: true Font: BaseFont: DECNDR+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: DECNDR+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WLTEQU+MTGUB FontSubset: true FirstChar: 98 LastChar: 98 FontDescriptor: FontName: WLTEQU+MTGUB Flags: Symbolic FontBBox: 0, -205, 879, 699 FontFile: true Font: BaseFont: UZSBMN+MinionPro-It FontSubset: true FirstChar: 3 LastChar: 250 FontDescriptor: FontName: UZSBMN+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CCVXXJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: CCVXXJ+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XNILIA+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: XNILIA+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: NLTBBQ+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 250 FontDescriptor: FontName: NLTBBQ+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: LCLVDP+BLEX FontSubset: true FirstChar: 18 LastChar: 19 FontDescriptor: FontName: LCLVDP+BLEX Flags: Symbolic FontBBox: -23, -2954, 1454, 762 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: MIJYAG+RBLMI FontSubset: true FirstChar: 12 LastChar: 95 FontDescriptor: FontName: MIJYAG+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: ITOYRU+MTGU FontSubset: true FirstChar: 97 LastChar: 98 FontDescriptor: FontName: ITOYRU+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: YEPIPF+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: YEPIPF+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: LGJNYH+MTSYN FontSubset: true FirstChar: 0 LastChar: 68 FontDescriptor: FontName: LGJNYH+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: BMZVXK+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: BMZVXK+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true XMP: chronic kidney disease, risk factors, genetic association study, single nucleotide polymorphism, linkage disequilibrium, haplotype pdfTeX-1.40.15 1.5 application/pdf fgene-10-00118.tex Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Isabel Rodriguez and José M. 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