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Destination: 1 Item: Title: Evidence for virus tropism change and superinfection between pre- and post-LoC time points. Destination: 1 Item: Title: Virus maintained HLA-associated escape mutations. Destination: 1 Item: Title: Increased number of HIV-specific T-cell responses post-LoC. Destination: 1 Item: Title: Reduced antiviral capacity of CD8+ T cells after loss of virological control. Destination: 1 Item: Title: Elevated frequencies of CD38 and PD-1 expression in CD8+ T cells after LoC. Destination: 1 Item: Title: DISCUSSION Destination: 1 Item: Title: MATERIALS AND METHODS Destination: 1 Children: Item: Title: Study participants and samples. Destination: 1 Item: Title: Gag sequence evolution. Destination: 1 Item: Title: Determination of viral tropism. Destination: 1 Item: Title: IFN- ELISPOT. Destination: 1 Item: Title: Viral inhibition assay. Destination: 1 Item: Title: Flow cytometry. Destination: 1 Item: Title: Statistical analysis. 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