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Title:          Global proteomic and methylome analysis in human induced pluripotent stem cells reveals overexpression of a human TLR3 affecting proper innate immune response signaling. 
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      Title:  Global Proteomic and Methylome Analysis inHuman Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affe...
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       Item: 
        Title: Introduction
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       Item: 
        Title: Materials and Methods
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        Children: 
         Item: 
          Title: iPSC Cell Culture
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         Item: 
          Title: Proteomic Analysis for Global and MHC-1 Peptide Analysis
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           Item: 
            Title: Protein Solubilization and Quantification
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           Item: 
            Title: Peptides Preparation and Labeling with Isobaric Tags (Tandem Mass Tag 10-Plex)
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         Item: 
          Title: Liquid Chromatography-Tandem Mass Spectrometry
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         Item: 
          Title: Protein Identification and Quantification
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         Item: 
          Title: Illumina Infinium Methylation EPIC BeadChip
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         Item: 
          Title: Bisulfite Pyrosequencing
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         Item: 
          Title: Sequencing
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         Item: 
          Title: Lipopolysaccharide and Poly (I:C) Stimulation
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         Item: 
          Title: Cytoplasmic and Nuclear Protein Fraction Extraction
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         Item: 
          Title: Illuminex Cytokine Detection Array
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         Item: 
          Title: Lentiviral Production
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         Item: 
          Title: Western Blot
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         Item: 
          Title: Flow Cytometry
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         Item: 
          Title: Real Time PCR
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         Item: 
          Title: Statistical Analyses
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       Item: 
        Title: Results
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        Children: 
         Item: 
          Title: Global Proteomic Analysis of Patient (F1) and iPSC-Derived Fibroblasts (F2)
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         Item: 
          Title: Characterization of Adaptive and Innate Immune System in Human iPSC
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         Item: 
          Title: Human TLR3 Isoform Transcription Start Site Is Hypomethylated in Human iPSC-Derived Cells and Exclusively Expressed in Humans
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7
         Item: 
          Title: Human TLR3 Isoform Is Overexpressed in Most Human iPSC-Derived Cells Not Seen in Normal Human Tissue or Cells
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         Item: 
          Title: Human TLR3 Isoform Functions to Suppress NF-KB p65 Signaling Pathway in Response to Virus (Poly IC)
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       Item: 
        Title: Discussion
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        Title: Ethical Statement
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        Title: Acknowledgments
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        Title: Author Contributions
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       Item: 
        Title: Disclosure of Potential Conflicts of Interest
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       Item: 
        Title: References
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