f5f827c8bbe711da47377a7304da3afa pmc_30670959.pdf 6b1ee7dfd80d3a204e81db9f46b100bc14c3129b pmc_30670959.pdf caf3a08236744edc408d37bd898a968924b94973060844890377057f1d9f8b64 pmc_30670959.pdf Title: An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group Subject: Objective: Brain imaging communities focusing on different diseases have increasingly started to collaborate and to pool data to perform well-powered meta- and mega-analyses. Keywords: neuroimaging, MRI, IPD meta-analysis, mega-analysis, linear mixed-effect models Author: Odile A. van den Heuvel and Jos W. R. Twisk Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Jan 7 13:45:56 2019 CET ModDate: Mon Jan 7 13:49:36 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 234353 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ARUTGA+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 36 0 DVVZRE+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 41 0 ZXIEEQ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 58 0 DHWGRM+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 60 0 FVJWOD+HelveticaNeueLTStd-MdIt Type 1C Custom yes yes no 66 0 YEJVYS+MTSY Type 1C Custom yes yes no 163 0 GBAUGV+RMTMI Type 1C WinAnsi yes yes no 165 0 GOEXCD+MinionPro-Regular Type 1C Custom yes yes no 129 0 HPCMWE+MinionPro-It Type 1C Custom yes yes no 143 0 WUXYTC+HelveticaNeueLTStd-Md Type 1C Custom yes yes no 200 0 ONNALD+MinionPro-Bold Type 1C Custom yes yes no 209 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-08-10 12:59:48 CEST RepresentationInformation: pmc_30670959.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-03-02 04:33:09 CET Size: 234353 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 356 FreeObjects: 16 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@63440df3 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3aeaafa6 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@76a3e297 Children: Item: Title: Samples Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Item: Title: Image Acquisition and Processing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: Statistical Framework Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Meta-Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Mega-Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Linear Regression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Linear Mixed-Effects Model – Random-Intercept Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: Meta-Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Mega-Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Comparing Meta- and Mega-Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Children: Item: Title: Effect Sizes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Standard Error and 95% Confidence Intervals Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Goodness-of-Fit Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Info: Title: An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group Author: Odile A. van den Heuvel and Jos W. R. Twisk Subject: Objective: Brain imaging communities focusing on different diseases have increasingly started to collaborate and to pool data to perform well-powered meta- and mega-analyses. Keywords: neuroimaging, MRI, IPD meta-analysis, mega-analysis, linear mixed-effect models Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Jan 07 14:15:56 CET 2019 ModDate: Mon Jan 07 14:19:36 CET 2019 ID: 0xd600eba1c46fe7fd679447f1f0b202b3, 0x51ac54dcdd697b48b4a5edc27dadf850 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: GOEXCD+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 248 FontDescriptor: FontName: GOEXCD+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ONNALD+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 150 FontDescriptor: FontName: ONNALD+MinionPro-Bold Flags: Symbolic FontBBox: -8, -245, 969, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: FVJWOD+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 39 LastChar: 243 FontDescriptor: FontName: FVJWOD+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -133, -205, 995, 731 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: YEJVYS+MTSY FontSubset: true FirstChar: 0 LastChar: 68 FontDescriptor: FontName: YEJVYS+MTSY Flags: Symbolic FontBBox: 0, -133, 724, 551 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ARUTGA+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 37 LastChar: 124 FontDescriptor: FontName: ARUTGA+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -19, -214, 925, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: GBAUGV+RMTMI FontSubset: true FirstChar: 60 LastChar: 60 FontDescriptor: FontName: GBAUGV+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 682, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: WUXYTC+HelveticaNeueLTStd-Md FontSubset: true FirstChar: 0 LastChar: 150 FontDescriptor: FontName: WUXYTC+HelveticaNeueLTStd-Md Flags: Symbolic FontBBox: 0, -205, 918, 731 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: DVVZRE+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 150 FontDescriptor: FontName: DVVZRE+HelveticaNeueLTStd-Lt Flags: Serif, Symbolic FontBBox: -13, -214, 904, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ZXIEEQ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: ZXIEEQ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DHWGRM+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 252 FontDescriptor: FontName: DHWGRM+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HPCMWE+MinionPro-It FontSubset: true FirstChar: 39 LastChar: 243 FontDescriptor: FontName: HPCMWE+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 1003, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: dvips + MiKTeX GPL Ghostscript 9.0 neuroimaging, MRI, IPD meta-analysis, mega-analysis, linear mixed-effect models 2019-01-07T18:19:36+05:30 2019-01-07T18:15:56+05:30 LaTeX with hyperref package + hypdvips 2019-01-07T18:19:36+05:30 acddbceb-14d5-11e9-0000-83ed6d3a9370 uuid:c7274c64-d1bf-4445-a25e-a9da85903d47 application/pdf An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group Odile A. van den Heuvel and Jos W. R. Twisk Objective: Brain imaging communities focusing on different diseases have increasingly started to collaborate and to pool data to perform well-powered meta- and mega-analyses. Objective: Brain imaging communities focusing on different diseases have increasingly started to collaborate and to pool data to perform well-powered meta- and mega-analyses. neuroimaging MRI IPD meta-analysis mega-analysis linear mixed-effect models Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 186, 755 Annotation: Subtype: Link Rect: 474, 736, 551, 744 Annotation: Subtype: Link Rect: 465, 728, 508, 736 Annotation: Subtype: Link Rect: 508, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 457, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 31, 131, 38 Annotation: Subtype: Link Rect: 135, 30, 195, 38 Annotation: Subtype: Link Rect: 433, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 351, 160, 360 Annotation: Subtype: Link Rect: 79, 204, 160, 211 Annotation: Subtype: Link Rect: 104, 183, 160, 191 Annotation: Subtype: Link Rect: 176, 567, 551, 657 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