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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 3315334 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1083 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: Patients and Samples Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Peptides, Antibodies, and Tetramers Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Analysis of HDV Sequences and HLA Class I-Associated Viral Polymorphisms Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Prediction of HDV-Specific CD8+ T-Cell Epitopes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Peptide-Specific CD8+ T-Cell Lines Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Intracellular IFN Gamma Staining Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: HLA Class I Tetramer-Based Analysis and Cell Enrichment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Children: Item: Title: Identification of HLA Class I–Associated Viral Sequence Polymorphisms in L-HDAg Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Validation of CD8+ T-Cell Epitopes and Viral Escape Mutations in L-HDAg Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Viral Evolution During Superinfection With HDV Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: HDV Sequence Polymorphisms Are Associated With Infrequent HLA Class I Alleles Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: HDV-Specific CD8+ T Cells Are Maintained at Very Low Frequencies After Viral Escape Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Info: Title: Mutations in Hepatitis D Virus Allow It 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254 FontDescriptor: FontName: ILMPNL+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ILNABO+AdvTT9cc80a3e.I FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: ILNABO+AdvTT9cc80a3e.I Flags: Nonsymbolic FontBBox: -125, -208, 979, 885 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1053/j.gastro.2019.02.003 Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level Hadi Karimzadeh Muthamia M. Kiraithe Valerie Oberhardt Elahe Salimi Alizei Jan Bockmann Julian Schulze zur Wiesch Bettina Budeus Daniel Hoffmann Heiner Wedemeyer Markus Cornberg Adalbert Krawczyk Jassin Rashidi-Alavijeh Francisco Rodríguez-Frías Rosario Casillas Maria Buti Antonina Smedile Seyed Moayed Alavian Andreas Heinold Florian Emmerich Marcus Panning Emma Gostick David A. Price Jörg Timm Maike Hofmann Bijan Raziorrouh Robert Thimme Ulrike Protzer Michael Roggendorf Christoph Neumann-Haefelin Cytotoxic T Cell MHC Class I TCR Antigen Presentation Gastroenterology, 156 (2019) 1820-1833. doi:10.1053/j.gastro.2019.02.003 Elsevier, Inc journal Gastroenterology © 2019 by the AGA Institute. Published by Elsevier Inc. 0016-5085 156 6 May 2019 1820-1833 1820 1833 10.1053/j.gastro.2019.02.003 https://doi.org/10.1053/j.gastro.2019.02.003 2010-04-23 true 10.1053/j.gastro.2019.02.003 elsevier.com sciencedirect.com VoR 6.5 10.1053/j.gastro.2019.02.003 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2019-04-16T15:25:55+05:30 2019-04-16T15:31:42+05:30 2019-04-16T15:31:42+05:30 True Acrobat Distiller 8.1.0 (Windows) uuid:fc44def8-7fe4-43b1-89b8-91c8f972b677 uuid:ee6368b3-89e5-4ca7-bdae-d9a5a93ab8a6 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1820 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 149, 628, 154, 640 Destination: null Annotation: Subtype: Link Rect: 157, 628, 162, 640 Destination: null Annotation: Subtype: Link Rect: 164, 628, 174, 640 Destination: null Annotation: Subtype: Link Rect: 176, 628, 176, 640 Destination: 1 Annotation: Subtype: Link Rect: 176, 628, 176, 640 Destination: 1 Annotation: Subtype: Link Rect: 176, 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