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Title:          New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Author:         Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Carl A Melbourne, Chiara Batini, Katherine A Fawcett, Kijoung Song, Phuwanat Sakornsakolpat, Xingnan Li, Ruth Boxall, Nicola F Reeve, Ma’en Obeidat, Jing Hua Zhao, Matthias Wielscher, , Stefan Weiss, Katherine A Kentistou, James P Cook, Benjamin B Sun, Jian Zhou, Jennie Hui, Stefan Karrasch, Medea Imboden, Sarah E Harris, Jonathan Marten, Stefan Enroth, Shona M Kerr, Ida Surakka, Veronique Vitart, Terho Lehtimäki, Richard J Allen, Per S Bakke, Terri H Beaty, Eugene R Bleecker, Yohan Bossé, Corry-Anke Brandsma, Zhengming Chen, James D Crapo, John Danesh, Dawn L DeMeo, Frank Dudbridge, Ralf Ewert, Christian Gieger, Amund Gulsvik, Anna L Hansell, Ke Hao, Joshua D Hoffman, John E Hokanson, Georg Homuth, Peter K Joshi, Philippe Joubert, Claudia Langenberg, Xuan Li, Liming Li, Kuang Lin, Lars Lind, Nicholas Locantore, Jian’an Luan, Anubha Mahajan, Joseph C Maranville, Alison Murray, David C Nickle, Richard Packer, Margaret M Parker, Megan L Paynton, David J Porteous, Dmitry Prokopenko, Dandi Qiao, Rajesh Rawal, Heiko Runz, Ian Sayers, Don D Sin, Blair H Smith, María Soler Artigas, David Sparrow, Ruth Tal-Singer, Paul RHJ Timmers, Maarten Van den Berge, John C Whittaker, Prescott G Woodruff, Laura M Yerges-Armstrong, Olga G Troyanskaya, Olli T Raitakari, Mika Kähönen, Ozren Polasek, Ulf Gyllensten, Igor Rudan, Ian J Deary, Nicole M Probst-Hensch, Holger Schulz, Alan L James, James F Wilson, Beate Stubbe, Eleftheria Zeggini, Marjo-Riitta Jarvelin, Nick Wareham, Edwin K Silverman, Caroline Hayward, Andrew P Morris, Adam S Butterworth, Robert A Scott, Robin G Walters, Deborah A Meyers, Michael H Cho, David P Strachan, Ian P Hall, Martin D Tobin, Louise V WainUnderstanding Society Scientific Group
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     Item: 
      Title: Abstract
     Item: 
      Title: Editorial summary:
     Item: 
      Title: Introduction
     Item: 
      Title: Results
      Children: 
       Item: 
        Title: 139 new signals for lung function
       Item: 
        Title: A total of 279 signals of association for lung function
       Item: 
        Title: Identification of putative causal genes
       Item: 
        Title: Pathway analysis
       Item: 
        Title: Functional enrichment analyses
       Item: 
        Title: Drug targets 
       Item: 
        Title: Association with FEV1/FVC and COPD in multiple ancestries
       Item: 
        Title: Pleiotropy and phenome-wide association studies
     Item: 
      Title: Discussion
     Item: 
      Title: Online Methods
      Children: 
       Item: 
        Title: Study Design Overview and rationale
       Item: 
        Title: UK Biobank
       Item: 
        Title: SpiroMeta consortium
       Item: 
        Title: Meta-analyses
       Item: 
        Title: Selection of new signals using conditional analyses
       Item: 
        Title: Assessment of previously reported lung function signals
       Item: 
        Title: Effect on COPD susceptibility   genetic risk score in multiple ancestries
       Item: 
        Title: Effects on smoking behavior
       Item: 
        Title: Smoking interaction
       Item: 
        Title: Proportion of variance explained
       Item: 
        Title: Fine-mapping
       Item: 
        Title: Implication of potentially causal genes
        Children: 
         Item: 
          Title: Annotation of deleterious variants
         Item: 
          Title: Gene expression and protein levels
       Item: 
        Title: Pathway analysis
       Item: 
        Title: Functional enrichment analyses
       Item: 
        Title: Drug targets
       Item: 
        Title: Phenome-wide association studies
     Item: 
      Title: References
     Item: 
      Title: Figure 1:
     Item: 
      Title: Figure 2:
     Item: 
      Title: Figure 3:
     Item: 
      Title: Figure 4:
     Item: 
      Title: Figure 5:
     Item: 
      Title: Table 1:
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