a1eeabbad8810e0130339ed0100d7687 pmc_30871504.pdf db245f7c86145c1b8e37ab11d4ea86a9e311aae0 pmc_30871504.pdf 2e7384e91d399435c24e97790e2385524a53b574f2457a219cacf58224594242 pmc_30871504.pdf Title: Immune reactivity to Trypanosoma cruzi chimeric proteins for Chagas disease diagnosis in immigrants living in a non-endemic setting Subject: BMC Infectious Diseases, 2019, doi:10.1186/s12879-019-3872-z Keywords: Chagas disease,Trypanosoma cruzi,Chimeric antigens,Immunoassay,Accuracy Author: Eva Dopico Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Tue Mar 12 03:05:56 2019 CET ModDate: Thu Mar 14 15:27:54 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1204813 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NPOFND+WbdlpdAdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 8 0 NPONAI+WpljcsAdvTTe45e47d2 Type 1C WinAnsi yes yes no 9 0 NPONAJ+PgpsyjAdvTT7329fd89.I Type 1C WinAnsi yes yes no 10 0 NPONAK+QqychjAdvTTb5929f4c Type 1C WinAnsi yes yes no 69 0 NPONAL+FsprffAdvTT99c4c969 Type 1C WinAnsi yes yes no 13 0 NPONBM+HnqlqsAdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 71 0 MyriadPro-Regular Type 1 Custom yes no no 12 0 NPOOBK+KlyjfgAdvTT86d47313+20 Type 1C WinAnsi yes yes no 11 0 NPOOAJ+KpnyxvAdvTT8861b38f.I Type 1C WinAnsi yes yes no 14 0 NPOOAI+XysjlmAdvTT86d47313 Type 1C WinAnsi yes yes no 15 0 NPOODK+DhskktAdvTT86d47313+03 Type 1C Custom yes yes yes 70 0 NPOOEL+DlphyrAdvTT86d47313+22 Type 1C Custom yes yes yes 72 0 NPPNHA+MdlrpbAdvTT99c4c969+20 Type 1C WinAnsi yes yes no 137 0 NPPNIA+NwrtdbAdvTTaf7f9f4f.B+20 Type 1C WinAnsi yes yes no 138 0 NPPNGP+VgpppfAdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 139 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-08-10 12:50:15 CEST RepresentationInformation: pmc_30871504.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-03-16 03:47:37 CET Size: 1204813 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR2' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR3' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR4' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR6' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR7' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR8' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR9' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR7' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR19' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR20' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig2' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig3' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig3' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig4' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR28' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR29' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 975451 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 975451 MIMEtype: application/pdf PDFMetadata: Objects: 359 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Study samples Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Recombinant antigens Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Immunoassays Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Children: Item: Title: Diagnostic performance Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Antigenic cross-reactivity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Abbreviations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Availability of the data and materials Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Authors’ contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Author information Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Ethics approval and consent to participate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Consent for publication Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Publisher’s Note Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Author details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Info: Title: Immune reactivity to Trypanosoma cruzi chimeric proteins for Chagas disease diagnosis in immigrants living in a non-endemic setting Author: Eva Dopico Subject: BMC Infectious Diseases, 2019, doi:10.1186/s12879-019-3872-z Keywords: Chagas disease,Trypanosoma cruzi,Chimeric antigens,Immunoassay,Accuracy Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Tue Mar 12 03:05:56 CET 2019 ModDate: Thu Mar 14 15:27:54 CET 2019 ID: 0xd70096f2fef2d922e6bdbbc59d049d68, 0x376ac690621f1b98fc29c16a0de5c9d2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 176 ImageHeight: 182 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 688 ImageHeight: 126 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 33 ImageHeight: 63 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1420 ImageHeight: 577 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 1181 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 855 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1420 ImageHeight: 650 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: NPONAK+QqychjAdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 250 FontDescriptor: FontName: NPONAK+QqychjAdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPOODK+DhskktAdvTT86d47313+03 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: NPOODK+DhskktAdvTT86d47313+03 Flags: Symbolic FontBBox: -281, -250, 906, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NPONBM+HnqlqsAdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: NPONBM+HnqlqsAdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPOFND+WbdlpdAdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: NPOFND+WbdlpdAdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPOOEL+DlphyrAdvTT86d47313+22 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: NPOOEL+DlphyrAdvTT86d47313+22 Flags: Symbolic FontBBox: -166, -260, 1031, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NPONAI+WpljcsAdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: NPONAI+WpljcsAdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPPNHA+MdlrpbAdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: NPPNHA+MdlrpbAdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -447, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPONAJ+PgpsyjAdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: NPONAJ+PgpsyjAdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPPNIA+NwrtdbAdvTTaf7f9f4f.B+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: NPPNIA+NwrtdbAdvTTaf7f9f4f.B+20 Flags: Nonsymbolic FontBBox: -468, -197, 1656, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPOOBK+KlyjfgAdvTT86d47313+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: NPOOBK+KlyjfgAdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -218, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPPNGP+VgpppfAdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: NPPNGP+VgpppfAdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -447, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -46, -250, 1126, 879 FontFile: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: NPONAL+FsprffAdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: NPONAL+FsprffAdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPOOAJ+KpnyxvAdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: NPOOAJ+KpnyxvAdvTT8861b38f.I Flags: Serif, Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NPOOAI+XysjlmAdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 237 FontDescriptor: FontName: NPOOAI+XysjlmAdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding XMP: Chagas disease,Trypanosoma cruzi,Chimeric antigens,Immunoassay,Accuracy Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) application/pdf 10.1186/s12879-019-3872-z BMC Infectious Diseases BMC Infectious Diseases, 2019, doi:10.1186/s12879-019-3872-z Chagas disease Trypanosoma cruzi Chimeric antigens Immunoassay Accuracy Immune reactivity to Trypanosoma cruzi chimeric proteins for Chagas disease diagnosis in immigrants living in a non-endemic setting Eva Dopico Rodrigo Pimenta Del-Rei Bertha Espinoza Itziar Ubillos Nilson Ivo Tonin Zanchin Elena Sulleiro Zaira Moure Paola Alejandra Fiorani Celedon Wayner Vieira Souza Edimilson Domingos Silva Yara Miranda Gomes Fred Luciano Neves Santos 2019-03-14T15:27:54+01:00 2019-03-12T10:05:56+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode 2019-03-14T15:27:54+01:00 uuid:6fede64a-28e9-4306-9014-de0e2d99bf60 uuid:ba80a273-32ea-4476-ac72-1dc4a0789435 default 1 converted uuid:666c33fb-773f-4c17-b6b1-d639dd5f5538 converted to PDF/A-2b pdfToolbox 2019-03-12T10:18:12+08:00 2 B Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. editorInfo Bag EditorInformation external Editor information: contains the name of each editor and his/her ORCID identifier. seriesEditorInfo Bag SeriesEditorInformation external Series editor information: contains the name of each series editor and his/her ORCID identifier. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. EditorInformation http://springernature.com/ns/xmpExtensions/2.0/editorInfo/ editor Specifies the types of editor information: name and ORCID of an editor. name Text Gives the name of an editor. orcid URI Gives the ORCID of an editor. SeriesEditorInformation http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/ seriesEditor Specifies the types of series editor information: name and ORCID of a series editor. name Text Gives the name of a series editor. orcid URI Gives the ORCID of a series editor. http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://ns.adobe.com/pdfx/1.3/ pdfx PDF/X ID Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 496, 635, 538, 677 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 239, 65, 357, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 182, 41, 321, 48 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 114, 135, 197, 143 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 212, 657, 216, 666 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 87, 633, 92, 642 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 97, 633, 101, 642 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 246, 597, 250, 606 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 253, 561, 258, 570 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 263, 561, 268, 570 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 179, 501, 184, 510 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 191, 465, 196, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 148, 453, 153, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 260, 441, 264, 450 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 202, 381, 211, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 256, 345, 266, 354 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 271, 345, 281, 354 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 164, 333, 174, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 181, 333, 190, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 321, 69, 330 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 139, 237, 149, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 93, 201, 103, 210 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 108, 201, 118, 210 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 97, 57, 107, 66 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 180, 57, 190, 66 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 354, 573, 359, 582 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 426, 321, 431, 330 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 430, 189, 440, 198 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 307, 141, 317, 150 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 324, 141, 333, 150 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 175, 57, 185, 66 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 438, 501, 443, 510 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 410, 489, 420, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 497, 489, 502, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 469, 429, 538, 438 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 417, 341, 426 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 402, 333, 407, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 512, 81, 517, 90 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 4 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 178, 633, 183, 642 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 101, 573, 110, 582 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 89, 525, 98, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 104, 525, 114, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 228, 489, 238, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 244, 489, 253, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 188, 381, 198, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 204, 381, 213, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 143, 369, 152, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 89, 297, 99, 306 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 130, 285, 140, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 433, 609, 443, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 371, 597, 381, 606 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 369, 549, 379, 558 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 483, 465, 492, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 498, 465, 508, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 415, 381, 425, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 372, 369, 382, 378 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 167, 645, 177, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 182, 645, 192, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 464, 138, 520, 146 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 129, 489, 137 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 120, 383, 128 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 383, 93, 533, 101 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 84, 439, 92 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 7 Thumb: true Checksum: dedce863 Type: CRC32 Checksum: a1eeabbad8810e0130339ed0100d7687 Type: MD5 Checksum: db245f7c86145c1b8e37ab11d4ea86a9e311aae0 Type: SHA-1