75f41c947572fa062c5b3cd89136de8f pmc_31031763.pdf 65a9c9284296ef2ab0ac7cbdd07e2016390e8114 pmc_31031763.pdf 2d65930b07706de78ed8548cdbe3d283db14e172b4b4a6f800d2252f5da4e5b7 pmc_31031763.pdf Title: Caveats and Pitfalls of SOX1 Autoantibody Testing With a Commercial Line Blot Assay in Paraneoplastic Neurological Investigations Subject: SOX1 autoantibodies are considered markers of small cell lung cancer (SCLC) and paraneoplastic neurological syndromes (PNS) and are usually determined by commercial line blot in many clinical services. Keywords: SOX1, autoantibodies, small-cell lung cancer, paraneoplastic neurological syndromes, line blot Author: Francesc Graus Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Apr 8 17:23:55 2019 CEST ModDate: Mon Apr 8 17:47:23 2019 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 5 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 1131895 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ZRDMDG+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 57 0 HLGGTS+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 51 0 PUGCYQ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 49 0 GRUWGK+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 32 0 XYFHNT+HelveticaNeueLTStd-Bd Type 1C WinAnsi yes yes no 27 0 UKMWOL+MinionPro-Regular Type 1C Custom yes yes no 69 0 IAAFVL+RMTMI Type 1C WinAnsi yes yes no 86 0 AUWHDP+MTSY Type 1C Custom yes yes yes 84 0 XTRGVR+MinionPro-Bold Type 1C Custom yes yes no 101 0 UADLTO+MTSYB Type 1C Custom yes yes no 114 0 FNANYW+MinionPro-It Type 1C Custom yes yes no 137 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-08-10 12:45:08 CEST RepresentationInformation: pmc_31031763.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-07-13 03:40:10 CEST Size: 1131895 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 186 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: ぃちぶづちぴび〠ちのつ〠ぐどぴてちぬぬび〠はて〠こくじ〱〠ぁふぴはちのぴどぢはつべ〠ごづびぴどので〠しどぴと〠ち〠ぃはねねづひっどちぬ〠がどのづ〠あぬはぴ〠ぁびびちべ〠どの〠ぐちひちのづはばぬちびぴどっ〠ぎづふひはぬはでどっちぬ〠ぉのぶづびぴどでちぴどはのび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Children: Item: Title: ぉのぴひはつふっぴどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: きづぴとはつび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: ぐちぴどづのぴび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: いどちでのはびぴどっ〠ぃひどぴづひどち〠てはひ〠こくじ〱〠ぁふぴはちのぴどぢはつどづび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: ぃづぬぬ〠あちびづつ〠ぁびびちべ Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: がどのづ〠あぬはぴ Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: げづびふぬぴび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: いどびっふびびどはの Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: ぅぴとどっび〠こぴちぴづねづのぴ Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: ぁふぴとはひ〠ぃはのぴひどぢふぴどはのび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: うふのつどので Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: ぁっにのはぷぬづつでねづのぴび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: げづてづひづのっづび Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Info: Title: Caveats and Pitfalls of SOX1 Autoantibody Testing With a Commercial Line Blot Assay in Paraneoplastic Neurological Investigations Author: Francesc Graus Subject: SOX1 autoantibodies are considered markers of small cell lung cancer (SCLC) and paraneoplastic neurological syndromes (PNS) and are usually determined by commercial line blot in many clinical services. Keywords: SOX1, autoantibodies, small-cell lung cancer, paraneoplastic neurological syndromes, line blot Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Apr 08 17:53:55 CEST 2019 ModDate: Mon Apr 08 18:17:23 CEST 2019 ID: 0x1132bad04eff029922bc01d974bd3384, 0xa99b6691499c5f4c98ab154a3c329230 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3071 ImageHeight: 2407 BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: GRUWGK+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 252 FontDescriptor: FontName: GRUWGK+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -13, -214, 826, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PUGCYQ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PUGCYQ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 751, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: UADLTO+MTSYB FontSubset: true FirstChar: 68 LastChar: 68 FontDescriptor: FontName: UADLTO+MTSYB Flags: Symbolic, AllCap FontBBox: 0, 0, 724, 387 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HLGGTS+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 243 FontDescriptor: FontName: HLGGTS+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: AUWHDP+MTSY FontSubset: true FirstChar: 14 LastChar: 20 FontDescriptor: FontName: AUWHDP+MTSY Flags: Symbolic FontBBox: 0, -133, 670, 503 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: UKMWOL+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: UKMWOL+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: XTRGVR+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: XTRGVR+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 823, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: IAAFVL+RMTMI FontSubset: true FirstChar: 62 LastChar: 62 FontDescriptor: FontName: IAAFVL+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 683, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ZRDMDG+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 241 FontDescriptor: FontName: ZRDMDG+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -49, -205, 891, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FNANYW+MinionPro-It FontSubset: true FirstChar: 3 LastChar: 241 FontDescriptor: FontName: FNANYW+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 903, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: XYFHNT+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 37 LastChar: 124 FontDescriptor: FontName: XYFHNT+HelveticaNeueLTStd-Bd Flags: Nonsymbolic FontBBox: -7, -214, 925, 786 FontFile3: true Encoding: WinAnsiEncoding XMP: dvips + MiKTeX GPL Ghostscript 9.0 SOX1, autoantibodies, small-cell lung cancer, paraneoplastic neurological syndromes, line blot 2019-04-08T21:17:23+05:30 2019-04-08T20:53:55+05:30 LaTeX with hyperref package + hypdvips 2019-04-08T21:17:23+05:30 d262cdea-5c6d-11e9-0000-062627537e41 uuid:2e41643d-d1dd-426e-926a-2f8123d4e3f5 application/pdf Caveats and Pitfalls of SOX1 Autoantibody Testing With a Commercial Line Blot Assay in Paraneoplastic Neurological Investigations Francesc Graus SOX1 autoantibodies are considered markers of small cell lung cancer (SCLC) and paraneoplastic neurological syndromes (PNS) and are usually determined by commercial line blot in many clinical services. SOX1 autoantibodies are considered markers of small cell lung cancer (SCLC) and paraneoplastic neurological syndromes (PNS) and are usually determined by commercial line blot in many clinical services. SOX1 autoantibodies small-cell lung cancer paraneoplastic neurological syndromes line blot Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 161, 755 Annotation: Subtype: Link Rect: 457, 736, 551, 744 Annotation: Subtype: Link Rect: 476, 728, 518, 736 Annotation: Subtype: Link Rect: 518, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 451, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 30, 117, 38 Annotation: Subtype: Link Rect: 120, 30, 180, 38 Annotation: Subtype: Link Rect: 444, 29, 551, 38 Annotation: Subtype: Link Rect: 87, 453, 160, 462 Annotation: Subtype: Link Rect: 75, 295, 160, 303 Annotation: Subtype: Link Rect: 74, 66, 160, 73 Annotation: Subtype: Link Rect: 176, 488, 551, 601 Annotation: Subtype: Link Rect: 176, 463, 259, 474 Annotation: Subtype: Link Rect: 271, 454, 328, 463 Annotation: Subtype: Link Rect: 336, 453, 385, 463 Page: Label: 2 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 114, 653, 121, 664 Destination: External Annotation: Subtype: Link Rect: 124, 653, 131, 664 Destination: External Annotation: Subtype: Link Rect: 119, 619, 126, 630 Destination: External Annotation: Subtype: Link Rect: 128, 619, 134, 630 Destination: External Annotation: Subtype: Link Rect: 279, 584, 285, 596 Destination: External Annotation: Subtype: Link Rect: 147, 538, 153, 550 Destination: External Annotation: Subtype: Link Rect: 156, 538, 163, 550 Destination: External Annotation: Subtype: Link Rect: 279, 493, 285, 504 Destination: External Annotation: Subtype: Link Rect: 47, 401, 53, 412 Destination: External Annotation: Subtype: Link Rect: 55, 401, 67, 412 Destination: External Annotation: Subtype: Link Rect: 244, 147, 255, 158 Destination: External Annotation: Subtype: Link Rect: 279, 78, 285, 90 Destination: External Annotation: Subtype: Link Rect: 505, 535, 512, 547 Destination: External Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 444, 29, 551, 38 Page: Label: 3 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 121, 216, 155, 227 Destination: External Annotation: Subtype: Link Rect: 178, 196, 208, 204 Destination: External Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 444, 29, 551, 38 Page: Label: 4 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 211, 399, 222, 410 Destination: External Annotation: Subtype: Link Rect: 166, 365, 173, 376 Destination: External Annotation: Subtype: Link Rect: 178, 365, 189, 376 Destination: External Annotation: Subtype: Link Rect: 225, 261, 236, 273 Destination: External Annotation: Subtype: Link Rect: 307, 708, 313, 720 Destination: External Annotation: Subtype: Link Rect: 323, 708, 334, 720 Destination: External Annotation: Subtype: Link Rect: 398, 662, 405, 674 Destination: External Annotation: Subtype: Link Rect: 352, 628, 359, 640 Destination: External Annotation: Subtype: Link Rect: 487, 571, 498, 582 Destination: External Annotation: Subtype: Link Rect: 411, 456, 422, 468 Destination: External Annotation: Subtype: Link Rect: 520, 388, 532, 399 Destination: External Annotation: Subtype: Link Rect: 331, 193, 338, 204 Destination: External Annotation: Subtype: Link Rect: 340, 193, 347, 204 Destination: External Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 444, 29, 551, 38 Page: Label: 5 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 150, 490, 222, 499 Annotation: Subtype: Link Rect: 96, 453, 177, 461 Annotation: Subtype: Link Rect: 70, 416, 184, 423 Annotation: Subtype: Link Rect: 292, 375, 56, 396 Annotation: Subtype: Link Rect: 70, 338, 167, 347 Annotation: Subtype: Link Rect: 70, 310, 164, 319 Annotation: Subtype: Link Rect: 70, 273, 171, 282 Annotation: Subtype: Link Rect: 292, 243, 56, 264 Annotation: Subtype: Link Rect: 70, 206, 167, 215 Annotation: Subtype: Link Rect: 104, 178, 182, 187 Annotation: Subtype: Link Rect: 341, 509, 411, 518 Annotation: Subtype: Link Rect: 331, 472, 418, 480 Annotation: Subtype: Link Rect: 331, 443, 427, 452 Annotation: Subtype: Link Rect: 331, 406, 416, 414 Annotation: Subtype: Link Rect: 331, 367, 413, 376 Annotation: Subtype: Link Rect: 405, 226, 431, 233 Annotation: Subtype: Link Rect: 431, 226, 463, 233 Annotation: Subtype: Link Rect: 463, 226, 499, 234 Annotation: Subtype: Link Rect: 499, 226, 522, 233 Annotation: Subtype: Link Rect: 522, 225, 549, 234 Annotation: Subtype: Link Rect: 43, 28, 117, 36 Annotation: Subtype: Link Rect: 120, 28, 180, 36 Annotation: Subtype: Link Rect: 444, 28, 551, 37 Checksum: cd9ae644 Type: CRC32 Checksum: 75f41c947572fa062c5b3cd89136de8f Type: MD5 Checksum: 65a9c9284296ef2ab0ac7cbdd07e2016390e8114 Type: SHA-1