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cannot be found Offset: 9671243 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib30' cannot be found Offset: 9671243 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1432 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Glucose Restriction Promotes Osteocyte Differentiation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Glucose Supply Modifies Osteoblast and Osteocyte Metabolism Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Glucose Restriction Increases the Mitochondrial DNA and Changes Mitochondrial Morphology Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Glucose Restriction Effects on Osteocyte Gene Expression Depend on AMPK Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: PGC-1 Mediates Enhanced Osteocytic Gene Expression in Response to Reduced Glucose Supply Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Limitations of Study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Supplemental Information Destination: 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Villena Pablo M. Garcia-Roves José Luis Rosa Francesc Ventura Molecular Mechanism of Behavior Molecular Physiology Specialized Functions of Cells ISCIENCE, 15 (2019) 79-94. doi:10.1016/j.isci.2019.04.015 Elsevier Inc. journal ISCIENCE © 2019 The Author(s). 2589-0042 15 31 May 2019 2019-05-31 79-94 79 94 10.1016/j.isci.2019.04.015 https://doi.org/10.1016/j.isci.2019.04.015 2010-04-23 true 10.1016/j.isci.2019.04.015 elsevier.com sciencedirect.com VoR 6.5 10.1016/j.isci.2019.04.015 noindex 25 true 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2019-05-28T03:22:07+05:30 2019-05-29T22:15:30+05:30 2019-05-29T22:15:30+05:30 True Acrobat Distiller 8.1.0 (Windows) uuid:856ebeda-b2f2-4346-8df2-e12e208b6855 uuid:43d4c8ab-dbce-402d-b638-25f0bd9523bf http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 79 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 455, 425, 501, 431 Annotation: Subtype: Link Rect: 455, 68, 520, 74 Annotation: Subtype: Link Rect: 455, 60, 501, 66 Annotation: 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Annotation: Subtype: Link Rect: 57, 602, 198, 609 Annotation: Subtype: Link Rect: 57, 594, 175, 601 Annotation: Subtype: Link Rect: 57, 586, 208, 593 Annotation: Subtype: Link Rect: 57, 578, 174, 585 Annotation: Subtype: Link Rect: 57, 557, 193, 564 Annotation: Subtype: Link Rect: 57, 549, 179, 556 Annotation: Subtype: Link Rect: 57, 541, 208, 548 Annotation: Subtype: Link Rect: 57, 533, 122, 540 Annotation: Subtype: Link Rect: 57, 511, 208, 518 Annotation: Subtype: Link Rect: 57, 503, 208, 510 Annotation: Subtype: Link Rect: 57, 495, 208, 502 Annotation: Subtype: Link Rect: 57, 487, 194, 494 Annotation: Subtype: Link Rect: 57, 479, 176, 486 Annotation: Subtype: Link Rect: 57, 471, 204, 478 Annotation: Subtype: Link Rect: 57, 463, 197, 470 Annotation: Subtype: Link Rect: 57, 455, 195, 462 Annotation: Subtype: Link Rect: 57, 447, 118, 454 Annotation: Subtype: Link Rect: 226, 672, 364, 679 Annotation: Subtype: Link Rect: 226, 664, 343, 671 Annotation: Subtype: Link Rect: 226, 656, 312, 663 Annotation: Subtype: Link Rect: 226, 640, 374, 647 Annotation: Subtype: Link Rect: 226, 632, 376, 639 Annotation: Subtype: Link Rect: 226, 624, 358, 631 Annotation: Subtype: Link Rect: 226, 616, 357, 623 Annotation: Subtype: Link Rect: 226, 608, 369, 615 Annotation: Subtype: Link Rect: 226, 600, 287, 607 Annotation: Subtype: Link Rect: 226, 583, 376, 590 Annotation: Subtype: Link Rect: 226, 576, 376, 582 Annotation: Subtype: Link Rect: 226, 568, 371, 574 Annotation: Subtype: Link Rect: 226, 560, 367, 566 Annotation: Subtype: Link Rect: 226, 552, 334, 559 Annotation: Subtype: Link Rect: 226, 535, 364, 542 Annotation: Subtype: Link Rect: 226, 527, 363, 534 Annotation: Subtype: Link Rect: 226, 519, 367, 526 Annotation: Subtype: Link Rect: 226, 511, 376, 518 Annotation: Subtype: Link Rect: 226, 503, 360, 510 Annotation: Subtype: Link Rect: 226, 495, 376, 502 Annotation: Subtype: Link Rect: 226, 487, 280, 494 Annotation: Subtype: Link Rect: 226, 471, 368, 478 Annotation: Subtype: Link Rect: 226, 463, 365, 470 Annotation: Subtype: Link Rect: 226, 455, 345, 462 Annotation: Subtype: Link Rect: 226, 447, 361, 454 Annotation: Subtype: Link Rect: 394, 672, 540, 679 Annotation: Subtype: Link Rect: 394, 664, 408, 671 Annotation: Subtype: Link Rect: 394, 644, 540, 651 Annotation: Subtype: Link Rect: 394, 636, 534, 643 Annotation: Subtype: Link Rect: 394, 628, 534, 635 Annotation: Subtype: Link Rect: 394, 620, 515, 627 Annotation: Subtype: Link Rect: 394, 612, 540, 619 Annotation: Subtype: Link Rect: 394, 604, 419, 611 Annotation: Subtype: Link Rect: 394, 583, 527, 590 Annotation: Subtype: Link Rect: 394, 576, 544, 582 Annotation: Subtype: Link Rect: 394, 568, 536, 574 Annotation: Subtype: Link Rect: 394, 560, 544, 566 Annotation: Subtype: Link Rect: 394, 552, 493, 559 Annotation: Subtype: Link Rect: 394, 531, 544, 538 Annotation: Subtype: Link Rect: 394, 523, 541, 530 Annotation: Subtype: Link Rect: 394, 515, 529, 522 Annotation: Subtype: Link Rect: 394, 507, 531, 514 Annotation: Subtype: Link Rect: 394, 499, 457, 506 Annotation: Subtype: Link Rect: 394, 479, 535, 486 Annotation: Subtype: Link Rect: 394, 471, 541, 478 Annotation: Subtype: Link Rect: 394, 463, 520, 470 Annotation: Subtype: Link Rect: 394, 455, 544, 462 Annotation: Subtype: Link Rect: 394, 447, 474, 454 Page: Label: 96 Sequence: 18 Page: Label: 97 Sequence: 19 Page: Label: 98 Sequence: 20 Page: Label: 99 Sequence: 21 Page: Label: 100 Sequence: 22 Page: Label: 101 Sequence: 23 Page: Label: 102 Sequence: 24 Page: Label: 103 Sequence: 25 Page: Label: 104 Sequence: 26 Page: Label: 105 Sequence: 27 Page: Label: 106 Sequence: 28 Thumb: true Page: Label: 107 Sequence: 29 Page: Label: 108 Sequence: 30 Page: Label: 109 Sequence: 31 Page: Label: 110 Sequence: 32 Page: Label: 111 Sequence: 33 Page: Label: 112 Sequence: 34 Page: Label: 113 Sequence: 35 Page: Label: 114 Sequence: 36 Page: Label: 115 Sequence: 37 Page: Label: 116 Sequence: 38 Page: Label: 117 Sequence: 39 Page: Label: 118 Sequence: 40 Page: Label: 119 Sequence: 41 Page: Label: 120 Sequence: 42 Checksum: cb0115f8 Type: CRC32 Checksum: dc411f39354a9efba604498ae2593556 Type: MD5 Checksum: 0b4904b22430237d4f7ad6b4b228be8a0955dc88 Type: SHA-1