e0128a50efd93a9e095f5b5200feaf83 pmc_31078141.pdf 78a8ae378f7007c075f1e80e1c04afb2e392e519 pmc_31078141.pdf e942ec0c39722d8e79cd2f333dbb9bc0a81182b8e5fb52039e5d96caf6aeb51d pmc_31078141.pdf Title: Evolution of the gut microbiome following acute HIV-1 infection Subject: Microbiome, 2019, doi:10.1186/s40168-019-0687-5 Keywords: Microbiome,HIV-1,acute HIV-1 infection,HIV-1 pathogenesis,AIDS Author: Muntsa Rocafort Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Sat May 11 01:17:29 2019 CEST ModDate: Sat May 11 10:44:11 2019 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 6311610 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GIIMIJ+GyrgvsAdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 8 0 GIINIE+PvybpkAdvTTe45e47d2 Type 1C WinAnsi yes yes no 9 0 GIINIF+JpwlxcAdvTTb5929f4c Type 1C WinAnsi yes yes no 55 0 GIINMK+HxmdtwAdvTT8861b38f.I Type 1C WinAnsi yes yes no 11 0 GIINLF+WjhtkmAdvTT99c4c969 Type 1C WinAnsi yes yes no 12 0 GIIONF+RqywrdAdvTT7329fd89.I Type 1C WinAnsi yes yes no 13 0 GIINLG+NbmqrfAdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 56 0 GIINLH+KjqcqkAdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 57 0 GIINMJ+VrpgwwAdvTT86d47313+20 Type 1C Custom yes yes yes 15 0 GIINLJ+TsgpkmAdvTT86d47313 Type 1C WinAnsi yes yes no 16 0 GIINLI+XtfpkcAdvTT1b53b5fb.I+20 Type 1C WinAnsi yes yes no 493 0 MyriadPro-Regular Type 1 Custom yes no no 10 0 GIIOPH+MhjntnAdvTT83913201.I Type 1C WinAnsi yes yes no 14 0 GIIOPG+QxmpqyAdvTT86d47313+22 Type 1C Custom yes yes yes 17 0 GILJGD+SjyxvpAdvTT8861b38f.I+20 Type 1C WinAnsi yes yes no 121 0 DOOFXD+PfxrdxHelvetica-Bold Type 1C WinAnsi yes yes no 122 0 GIMGIF+MdtxqdAdvTTe45e47d2+20 Type 1C WinAnsi yes yes no 149 0 GIMGLH+CjbqrwAdvTT43ccf47d+22 Type 1C Custom yes yes yes 185 0 GIMGKF+HbxtncAdvTT99c4c969+20 Type 1C WinAnsi yes yes no 186 0 GIMGKG+GvnppsAdvTT43ccf47d Type 1C WinAnsi yes yes no 187 0 GIMGNH+WhtrdbAdvTT86d47313+03 Type 1C Custom yes yes yes 209 0 GIMGNI+HbvdxrAdvTT86d47313+21 Type 1C WinAnsi yes yes no 210 0 GIMHAI+VkxbygAdvTT83913201.I+20 Type 1C WinAnsi yes yes no 234 0 GIMHDI+RxnqbwAdvTTaf7f9f4f.B+20 Type 1C WinAnsi yes yes no 267 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-08-10 12:44:10 CEST RepresentationInformation: pmc_31078141.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-03-16 03:46:00 CET Size: 6311610 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR2' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR3' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR12' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR19' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR19' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR23' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR27' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR28' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR29' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR31' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR32' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR34' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR23' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR35' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR35' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR32' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR28' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR29' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR28' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR20' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR36' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR37' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR34' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR34' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR23' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR38' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR40' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR41' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR42' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR43' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR44' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR45' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR46' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR47' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR48' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR49' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR50' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR51' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR52' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR53' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR54' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR55' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR56' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR56' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR54' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR57' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR58' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR52' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR59' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR52' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR60' cannot be found Offset: 6005772 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR61' cannot be found Offset: 6005772 MIMEtype: application/pdf PDFMetadata: Objects: 618 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: Study subjects Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: 16S rRNA gene sequencing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Children: Item: Title: Alpha diversity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Microbial genus composition Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Whole shotgun metagenome sequencing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Children: Item: Title: Alpha diversity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Microbial species composition Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Fecal virus shedding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Children: Item: Title: Experimental models and subjects’ details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Children: Item: Title: Human subjects Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Diagnosis of recent HIV-1 Infection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Study follow-up Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Method details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: Demographic and clinical data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 16S rRNA gene sequencing: DNA extraction, amplicon generation and sequencing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Whole genome sequencing (WGS): library preparation and sequencing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: 16S rRNA gene sequence analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Metagenomic sequence analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Detection of fecal virus shedding by qualitative RT-PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Cytokine quantification in plasma Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Cytokine quantification in feces Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Quantification and statistical analyses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Children: Item: Title: Ecological analysis of gut microbiota Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Analysis of gut microbiota composition Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Analysis on gut microbiota’s gene richness and metabolic functions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Microbial functional profile Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: Fecal virus shedding analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: Additional file Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Item: Title: Availability of data and materials Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3 Item: Title: Authors’ contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@32eebfca Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207 Item: Title: Publisher’s Note Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d Item: Title: Author details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@543c6f6d Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13eb8acf Info: Title: Evolution of the gut microbiome following acute HIV-1 infection Author: Muntsa Rocafort Subject: Microbiome, 2019, doi:10.1186/s40168-019-0687-5 Keywords: Microbiome,HIV-1,acute HIV-1 infection,HIV-1 pathogenesis,AIDS Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Sat May 11 01:17:29 CEST 2019 ModDate: Sat May 11 10:44:11 CEST 2019 ID: 0x6388de120708cd875e7733a0b2c28755, 0x548087876f3b1ffeb40b5fb90be7eae6 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 176 ImageHeight: 182 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 688 ImageHeight: 126 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 54 ImageHeight: 103 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1949 ImageHeight: 1586 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1949 ImageHeight: 1396 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1949 ImageHeight: 2099 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1949 ImageHeight: 1956 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: GIIMIJ+GyrgvsAdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: GIIMIJ+GyrgvsAdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINIE+PvybpkAdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: GIINIE+PvybpkAdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -46, -250, 1126, 879 FontFile: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: GIMHAI+VkxbygAdvTT83913201.I+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: GIMHAI+VkxbygAdvTT83913201.I+20 Flags: Nonsymbolic FontBBox: -447, -197, 1531, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINMK+HxmdtwAdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: GIINMK+HxmdtwAdvTT8861b38f.I Flags: Serif, Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIMHDI+RxnqbwAdvTTaf7f9f4f.B+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: GIMHDI+RxnqbwAdvTTaf7f9f4f.B+20 Flags: Nonsymbolic FontBBox: -468, -197, 1656, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINLF+WjhtkmAdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: GIINLF+WjhtkmAdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINLI+XtfpkcAdvTT1b53b5fb.I+20 FontSubset: true FirstChar: 32 LastChar: 151 FontDescriptor: FontName: GIINLI+XtfpkcAdvTT1b53b5fb.I+20 Flags: Nonsymbolic FontBBox: -447, -197, 1333, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIIONF+RqywrdAdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: GIIONF+RqywrdAdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIIOPH+MhjntnAdvTT83913201.I FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: GIIOPH+MhjntnAdvTT83913201.I Flags: Nonsymbolic FontBBox: -93, -250, 906, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINMJ+VrpgwwAdvTT86d47313+20 FontSubset: true FirstChar: 2 LastChar: 152 FontDescriptor: FontName: GIINMJ+VrpgwwAdvTT86d47313+20 Flags: Symbolic FontBBox: -218, -218, 1291, 812 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GIINLJ+TsgpkmAdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 239 FontDescriptor: FontName: GIINLJ+TsgpkmAdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIIOPG+QxmpqyAdvTT86d47313+22 FontSubset: true FirstChar: 1 LastChar: 139 FontDescriptor: FontName: GIIOPG+QxmpqyAdvTT86d47313+22 Flags: Symbolic FontBBox: -166, -260, 1031, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GIMGNH+WhtrdbAdvTT86d47313+03 FontSubset: true FirstChar: 1 LastChar: 6 FontDescriptor: FontName: GIMGNH+WhtrdbAdvTT86d47313+03 Flags: Symbolic FontBBox: -281, -250, 906, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GIMGNI+HbvdxrAdvTT86d47313+21 FontSubset: true FirstChar: 32 LastChar: 153 FontDescriptor: FontName: GIMGNI+HbvdxrAdvTT86d47313+21 Flags: Nonsymbolic FontBBox: -20, -208, 1208, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIMGIF+MdtxqdAdvTTe45e47d2+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: GIMGIF+MdtxqdAdvTTe45e47d2+20 Flags: Nonsymbolic FontBBox: -447, -197, 1302, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINIF+JpwlxcAdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 252 FontDescriptor: FontName: GIINIF+JpwlxcAdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINLG+NbmqrfAdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 151 FontDescriptor: FontName: GIINLG+NbmqrfAdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -447, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIINLH+KjqcqkAdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: GIINLH+KjqcqkAdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GILJGD+SjyxvpAdvTT8861b38f.I+20 FontSubset: true FirstChar: 32 LastChar: 151 FontDescriptor: FontName: GILJGD+SjyxvpAdvTT8861b38f.I+20 Flags: Nonsymbolic FontBBox: -218, -218, 1385, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIMGLH+CjbqrwAdvTT43ccf47d+22 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: GIMGLH+CjbqrwAdvTT43ccf47d+22 Flags: Symbolic FontBBox: -166, -166, 708, 864 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DOOFXD+PfxrdxHelvetica-Bold FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: DOOFXD+PfxrdxHelvetica-Bold Flags: Nonsymbolic, ForceBold FontBBox: -170, -228, 1003, 962 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIMGKF+HbxtncAdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: GIMGKF+HbxtncAdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -447, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GIMGKG+GvnppsAdvTT43ccf47d FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: GIMGKG+GvnppsAdvTT43ccf47d Flags: Serif, Nonsymbolic FontBBox: -20, -250, 1010, 864 FontFile3: true Encoding: WinAnsiEncoding XMP: Microbiome,HIV-1,acute HIV-1 infection,HIV-1 pathogenesis,AIDS Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) application/pdf 10.1186/s40168-019-0687-5 Microbiome Microbiome, 2019, doi:10.1186/s40168-019-0687-5 Microbiome HIV-1 acute HIV-1 infection HIV-1 pathogenesis AIDS Evolution of the gut microbiome following acute HIV-1 infection Muntsa Rocafort Marc Noguera-Julian Javier Rivera Lucía Pastor Yolanda Guillén Jost Langhorst Mariona Parera Inacio Mandomando Jorge Carrillo Víctor Urrea Cristina Rodríguez Maria Casadellà Maria Luz Calle Bonaventura Clotet Julià Blanco Denise Naniche Roger Paredes 2019-05-11T10:44:11+02:00 2019-05-11T07:17:29+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode 2019-05-11T10:44:11+02:00 uuid:9f855e4a-8431-4b3e-b3b4-f39f23a9006f uuid:fc4ce3a7-c330-41de-8035-d705a8e434ff default 1 converted uuid:e3dfc8c8-b3c6-43cf-810a-8cf0750d9183 converted to PDF/A-2b pdfToolbox 2019-05-11T07:22:02+08:00 2 B Muntsa Rocafort http://orcid.org/0000-0002-2991-1444 Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. editorInfo Bag EditorInformation external Editor information: contains the name of each editor and his/her ORCID identifier. seriesEditorInfo Bag SeriesEditorInformation external Series editor information: contains the name of each series editor and his/her ORCID identifier. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. EditorInformation http://springernature.com/ns/xmpExtensions/2.0/editorInfo/ editor Specifies the types of editor information: name and ORCID of an editor. name Text Gives the name of an editor. orcid URI Gives the ORCID of an editor. SeriesEditorInformation http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/ seriesEditor Specifies the types of series editor information: name and ORCID of a series editor. name Text Gives the name of a series editor. orcid URI Gives the ORCID of a series editor. http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://ns.adobe.com/pdfx/1.3/ pdfx PDF/X ID Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 496, 635, 538, 677 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 133, 599, 142, 608 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 80, 230, 85, 240 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 174, 206, 179, 216 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 185, 206, 190, 216 Flags: Print AppearanceDictionary: true Destination: 264 Annotation: Subtype: Link Rect: 497, 278, 502, 288 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 507, 278, 517, 288 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 523, 278, 533, 288 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 507, 254, 517, 264 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 523, 254, 533, 264 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 307, 134, 317, 144 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 327, 122, 331, 132 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 336, 122, 346, 132 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 352, 122, 362, 132 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 507, 98, 517, 108 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 523, 98, 533, 108 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 239, 65, 357, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 182, 41, 321, 48 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 114, 144, 176, 152 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 193, 645, 203, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 100, 501, 110, 510 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 117, 501, 127, 510 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 197, 465, 207, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 393, 69, 402 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 96, 369, 106, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 231, 273, 241, 282 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 248, 273, 258, 282 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 283, 249, 288, 258 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 56, 237, 66, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 72, 237, 82, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 88, 237, 98, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 475, 501, 480, 510 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 347, 429, 352, 438 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 481, 357, 486, 366 Flags: Print AppearanceDictionary: true Destination: 53 Annotation: Subtype: Link Rect: 333, 309, 338, 318 Flags: Print AppearanceDictionary: true Destination: 53 Annotation: Subtype: Link Rect: 445, 201, 450, 210 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 360, 105, 365, 114 Flags: Print AppearanceDictionary: true Destination: 61 Annotation: Subtype: Link Rect: 466, 81, 471, 90 Flags: Print AppearanceDictionary: true Destination: 61 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 239, 116, 247, 123 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 209, 81, 214, 90 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 416, 153, 421, 162 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 497, 141, 502, 150 Flags: Print AppearanceDictionary: true Destination: 72 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 117, 225, 122, 234 Flags: Print AppearanceDictionary: true Destination: 89 Annotation: Subtype: Link Rect: 191, 201, 196, 210 Flags: Print AppearanceDictionary: true Destination: 89 Annotation: Subtype: Link Rect: 276, 153, 281, 162 Flags: Print AppearanceDictionary: true Destination: 89 Annotation: Subtype: Link Rect: 213, 93, 218, 102 Flags: Print AppearanceDictionary: true Destination: 89 Annotation: Subtype: Link Rect: 423, 201, 429, 210 Flags: Print AppearanceDictionary: true Destination: 89 Annotation: Subtype: Link Rect: 374, 129, 379, 138 Flags: Print AppearanceDictionary: true Destination: 251 Thumb: true Page: Sequence: 6 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 59, 477, 69, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 75, 477, 84, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 91, 477, 100, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 162, 417, 167, 426 Flags: Print AppearanceDictionary: true Destination: 117 Annotation: Subtype: Link Rect: 146, 381, 151, 390 Flags: Print AppearanceDictionary: true Destination: 117 Annotation: Subtype: Link Rect: 241, 357, 246, 366 Flags: Print AppearanceDictionary: true Destination: 117 Annotation: Subtype: Link Rect: 276, 213, 285, 222 Flags: Print AppearanceDictionary: true Destination: 136 Annotation: Subtype: Link Rect: 139, 165, 148, 174 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 155, 165, 164, 174 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 240, 105, 250, 114 Flags: Print AppearanceDictionary: true Destination: 136 Annotation: Subtype: Link Rect: 332, 429, 342, 438 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 531, 381, 536, 390 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 358, 249, 363, 258 Flags: Print AppearanceDictionary: true Destination: 147 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 56, 213, 61, 222 Flags: Print AppearanceDictionary: true Destination: 251 Annotation: Subtype: Link Rect: 283, 177, 288, 186 Flags: Print AppearanceDictionary: true Destination: 251 Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 128, 105, 138, 114 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 216, 105, 225, 114 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 226, 57, 236, 66 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 245, 57, 254, 66 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 190, 537, 200, 546 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 105, 93, 114, 102 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 354, 489, 358, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 365, 489, 374, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 380, 489, 390, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 396, 489, 406, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 385, 477, 394, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 471, 453, 475, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 482, 453, 492, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 418, 357, 428, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 435, 357, 444, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 451, 357, 461, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 468, 357, 478, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 469, 333, 479, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 453, 285, 463, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 468, 285, 478, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 331, 225, 341, 234 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 400, 141, 410, 150 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 415, 141, 425, 150 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 100, 693, 109, 702 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 115, 693, 125, 702 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 173, 657, 183, 666 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 241, 633, 251, 642 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 263, 453, 273, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 109, 285, 119, 294 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 451, 441, 461, 450 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 467, 441, 477, 450 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 369, 309, 374, 318 Flags: Print AppearanceDictionary: true Destination: 251 Thumb: true Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 264, 453, 273, 462 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 218, 429, 228, 438 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 141, 393, 151, 402 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 165, 237, 175, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 129, 69, 138 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 523, 669, 533, 678 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 366, 633, 512, 642 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 523, 633, 533, 642 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 307, 609, 317, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 445, 561, 538, 570 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 549, 326, 558 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 231, 225, 241, 234 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 96, 213, 105, 222 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 307, 681, 317, 690 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 400, 609, 410, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 471, 609, 481, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 340, 537, 350, 546 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 406, 381, 416, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 461, 189, 471, 198 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 349, 177, 359, 186 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 275, 669, 285, 678 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 275, 537, 285, 546 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 97, 429, 106, 438 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 103, 369, 113, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 191, 93, 200, 102 Flags: Print AppearanceDictionary: true Destination: 281 Annotation: Subtype: Link Rect: 309, 478, 366, 486 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 422, 466, 530, 474 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 457, 365, 465 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 364, 266, 529, 274 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 257, 381, 265 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 17 Thumb: true Checksum: 21913c2a Type: CRC32 Checksum: e0128a50efd93a9e095f5b5200feaf83 Type: MD5 Checksum: 78a8ae378f7007c075f1e80e1c04afb2e392e519 Type: SHA-1