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780 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Specific patterns of brain alterations underlie distinct clinical profiles in Huntington's disease Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Material and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: Participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Symptom assessments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: MRI data acquisition Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: MRI data processing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: Grey matter structure measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Voxel-based morphometry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Cortical thickness Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: White matter microstructure measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Linked independent component analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Relationship between neuroimaging components and behavioural measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Linked independent component analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Relationship between neuroimaging components and behavioural measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Children: Item: Title: Relationship between symptom domains and neuroimaging independent components Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Spatial maps associated with symptom domains Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Contribution of neuroimaging modalities in each symptom profile Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Contribution of premanifest and manifest individuals in each symptom domain Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Integration of main findings and concluding remarks Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Declaration of Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Info: Title: Specific patterns of brain alterations underlie distinct clinical profiles in Huntington's disease Author: Clara Garcia-Gorro Subject: NeuroImage: Clinical, 23 (2019) 101900. doi:10.1016/j.nicl.2019.101900 Keywords: Linked ICA; Data fusion; Huntington's disease; Neurodegeneration; Clinical profiles; Structural MRI; Creator: Elsevier CreationDate: Wed Aug 28 09:16:34 CEST 2019 ModDate: Wed Aug 28 09:16:34 CEST 2019 ID: 0x7591f9a185aaa376f29c885e6ae5a055, 0x5ff6887b728b9d459770807a153c8b26 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: 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Beckmann Ruth de Diego-Balaguer Estela Camara Linked ICA Data fusion Huntington's disease Neurodegeneration Clinical profiles Structural MRI Elsevier NeuroImage: Clinical, 23 (2019) 101900. doi:10.1016/j.nicl.2019.101900 journal NeuroImage: Clinical © 2019 Published by Elsevier Inc. 2213-1582 23 2019 101900 101900 10.1016/j.nicl.2019.101900 https://doi.org/10.1016/j.nicl.2019.101900 2010-04-23 true 10.1016/j.nicl.2019.101900 elsevier.com sciencedirect.com 6.5 10.1016/j.nicl.2019.101900 2010-04-23 true noindex elsevier.com sciencedirect.com VoR Elsevier 2019-08-28T07:16:34Z 2019-08-28T07:16:34Z 2019-08-28T07:16:34Z True Linked ICA; Data fusion; Huntington's disease; Neurodegeneration; Clinical profiles; Structural MRI; uuid:b4429e08-ed93-46a4-8750-ed3c625382a2 uuid:de8879fe-2f5a-40bd-80ab-53ac915515b4 http://creativecommons.org/licenses/BY-NC-ND/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 322, 723, 369, 731 Annotation: Subtype: Link Rect: 276, 668, 402, 676 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526 Annotation: Subtype: Link Rect: 391, 487, 533, 494 Annotation: Subtype: Link Rect: 378, 455, 520, 462 Checksum: 7c0d10cd Type: CRC32 Checksum: 7503cb345cae896fb1560cb658da60e3 Type: MD5 Checksum: 267e3cd769960acab9c2e4f4b2f0346431760972 Type: SHA-1