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Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Children: Item: Title: 1. Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: 2. Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: 2.1. Trial Design and Study Participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: 2.2. Procedures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: 2.3. Outcomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: 2.4. Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: 3. Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: 3.1. Participants Enrolled in the Study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: 3.2. Both ChAdV63.HIVconsv and MVA.HIVconsv vaccines were safe and well tolerated Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: 3.3. ChAdV63.HIVconsv-MVA.HIVconsv regimen induced high frequencies of T cells against conserved regions of HIV-1 in all va... Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: 3.4. ChAdV63.HIVconsv-MVA.HIVconsv vaccination elicited responses to multiple epitopes within the HIVconsv immunogen Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: 3.5. ChAdV63.HIVconsv-MVA.HIVconsv vaccination shifts immunodominance T-cell patterns towards conserved regions of the HIV-... Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: 3.6. Early cART preserves antiviral function of CD8+ T cells and might contribute to an efficacious vaccine response Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: 3.7. Early cART, but not HIVconsv vaccination limits the size of latent viral reservoir Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: 4. Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Declaration of Competing Interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Role of the Funding Source Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Members of the BCN 01 Study group Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Author's Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Info: Title: Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study) Creator: Elsevier Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Tue Jun 25 08:32:42 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Manzardo Alvaro Sanchez-Bernabeu Pep Coll Sara Morón-López Maria C. Puertas Miriam Rosas-Umbert Patricia Cobarsi Roser Escrig Núria Perez-Alvarez Irene Ruiz Cristina Rovira Michael Meulbroek Alison Crook Nicola Borthwick Edmund G. Wee Hongbing Yang Jose M. Miró Lucy Dorrell Bonaventura Clotet Javier Martinez-Picado Christian Brander Tomáš Hanke BCN 01 study group EClinicalMedicine, 11 (2019) 65-80. doi:10.1016/j.eclinm.2019.05.009 journal EClinicalMedicine (c) 2019 Elsevier Ltd All rights reserved Elsevier Ltd 2589-5370 11 C May-June 2019 201905/06 65-80 65 80 10.1016/j.eclinm.2019.05.009 https://doi.org/10.1016/j.eclinm.2019.05.009 doi:10.1016/j.eclinm.2019.05.009 2010-04-23 true 10.1016/j.eclinm.2019.05.009 elsevier.com sciencedirect.com VoR 6.5 10.1016/j.eclinm.2019.05.009 noindex 2010-04-23 true elsevier.com sciencedirect.com Elsevier True Pages: Page: Label: 65 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 111, 577, 115, 588 Destination: 610 Annotation: Subtype: Link Rect: 117, 577, 121, 588 Destination: 610 Annotation: Subtype: Link Rect: 123, 577, 126, 588 Destination: 610 Annotation: Subtype: Link Rect: 128, 573, 133, 585 Destination: 610 Annotation: Subtype: Link Rect: 234, 577, 238, 588 Destination: 610 Annotation: 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Subtype: Link Rect: 351, 595, 456, 601 Annotation: Subtype: Link Rect: 489, 579, 561, 585 Annotation: Subtype: Link Rect: 325, 571, 372, 577 Annotation: Subtype: Link Rect: 492, 555, 561, 561 Annotation: Subtype: Link Rect: 325, 547, 372, 554 Annotation: Subtype: Link Rect: 517, 531, 561, 538 Annotation: Subtype: Link Rect: 325, 523, 397, 530 Annotation: Subtype: Link Rect: 325, 499, 429, 506 Annotation: Subtype: Link Rect: 474, 475, 561, 482 Annotation: Subtype: Link Rect: 325, 467, 381, 474 Annotation: Subtype: Link Rect: 530, 444, 561, 450 Annotation: Subtype: Link Rect: 325, 436, 392, 442 Annotation: Subtype: Link Rect: 420, 412, 561, 418 Annotation: Subtype: Link Rect: 449, 380, 543, 386 Annotation: Subtype: Link Rect: 491, 364, 561, 370 Annotation: Subtype: Link Rect: 325, 356, 368, 362 Annotation: Subtype: Link Rect: 509, 340, 561, 346 Annotation: Subtype: Link Rect: 325, 332, 388, 338 Annotation: Subtype: Link Rect: 407, 308, 531, 314 Annotation: Subtype: Link Rect: 433, 284, 543, 291 Annotation: Subtype: Link Rect: 387, 260, 517, 267 Annotation: Subtype: Link Rect: 471, 244, 561, 251 Annotation: Subtype: Link Rect: 325, 236, 364, 243 Annotation: Subtype: Link Rect: 400, 204, 538, 211 Annotation: Subtype: Link Rect: 491, 188, 561, 195 Annotation: Subtype: Link Rect: 325, 181, 372, 187 Annotation: Subtype: Link Rect: 482, 157, 561, 163 Annotation: Subtype: Link Rect: 325, 149, 357, 155 Annotation: Subtype: Link Rect: 342, 117, 452, 123 Annotation: Subtype: Link Rect: 530, 101, 561, 107 Annotation: Subtype: Link Rect: 325, 93, 432, 99 Annotation: Subtype: Link Rect: 353, 69, 451, 75 Page: Label: 80 Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 178, 730, 284, 737 Annotation: Subtype: Link Rect: 48, 722, 69, 729 Annotation: Subtype: Link Rect: 235, 707, 284, 713 Annotation: Subtype: Link Rect: 48, 699, 138, 705 Annotation: Subtype: Link Rect: 156, 675, 264, 681 Annotation: Subtype: Link Rect: 76, 643, 176, 649 Annotation: Subtype: Link Rect: 103, 627, 240, 633 Annotation: Subtype: Link Rect: 477, 715, 552, 721 Annotation: Subtype: Link Rect: 316, 707, 373, 713 Annotation: Subtype: Link Rect: 316, 699, 552, 705 Annotation: Subtype: Link Rect: 316, 691, 552, 697 Annotation: Subtype: Link Rect: 316, 683, 552, 689 Annotation: Subtype: Link Rect: 316, 675, 471, 681 Annotation: Subtype: Link Rect: 490, 651, 552, 657 Annotation: Subtype: Link Rect: 316, 643, 438, 649 Checksum: b5b36cb4 Type: CRC32 Checksum: 5036a7fe7db8b2a7422afcabb6f58798 Type: MD5 Checksum: ddc438563cc7011a2f44c779762183624abfb102 Type: SHA-1