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Title:          Human Albumin Impairs Amyloid β-peptide Fibrillation Through its C-terminus: From docking Modeling to Protection Against Neurotoxicity in Alzheimer's disease
Subject:        Computational and Structural Biotechnology Journal, 17 (2019) 963-971. doi:10.1016/j.csbj.2019.06.017
Keywords:       Alzheimer's disease;  Amyloid;  Albumin;  β-Sheet;  Docking
Author:         Pol Picón-Pagès
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      Title: Human Albumin Impairs Amyloid β-„peptide Fibrillation Through its C-„terminus: From docking Modeling to Protection Against ...
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        Title: 1. Introduction
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        Title: 2. Methodology
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          Title: 2.1. Modeling of the Clusterin Peptide
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          Title: 2.2. Aβ1–42 -Docking Analyses
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          Title: 2.3. CTerm Synthesis
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          Title: 2.4. CTerm Analysis
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          Title: 2.5. CTerm Purification
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          Title: 2.6. Circular Dichroism (CD)
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          Title: 2.7. Amyloid Preparation
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          Title: 2.8. Reversed-Phase Chromatography Analysis of CTerm Effect on Aβ Aggregation
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          Title: 2.9. Reversed-Phase Chromatography Analysis of Control Peptide Effect on Aβ Aggregation
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          Title: 2.10. Transmission Electron Microscopy (TEM)
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          Title: 2.11. Cell Viability Assay by MTT Reduction
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          Title: 2.12. Aβ1–42 Binding to Neuronal Processes
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        Title: 3. Results
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          Title: 3.1. Albumin Binds Aß With Higher Affinity Than Clusterin
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          Title: 3.2. In silico Analysis of Aβ1–42-CTerm Interaction
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          Title: 3.3. In vitro Analysis of Aβ1–42-CTerm Interaction
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          Title: 3.4. CTerm Protects Neurons against Amyloid Neurotoxicity
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        Title: Declaration of interest
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   Type: CRC32
  Checksum: 90aa4d6b8de2e37c346fdd25e63ce333
   Type: MD5
  Checksum: f7815e77d53b03d22e2af9b9607f3401b337993b
   Type: SHA-1