3ca10ea5ace89590d461cc6403bed0b0  pmc_31723270.pdf
b216fe656e4f1dffec91d3a3f10241b0b7708557  pmc_31723270.pdf
f5a80123641b32eb79d30b26de6bfc9550fc745bd63fe8f2f3cdd2902436c780  pmc_31723270.pdf

Title:          Enamel Proteome shows that Gigantopithecus was an early diverging pongine.
Author:         Frido Welker, Jazmín Ramos-Madrigal, Martin Kuhlwilm, Wei Liao, Petra Gutenbrunner, Marc de Manuel, Diana Samodova, Meaghan Mackie, Morten E. Allentoft, Anne-Marie Bacon, Matthew J. Collins, Jürgen Cox, Carles Lalueza-Fox, Jesper V. Olsen, Fabrice Demeter, Wei Wang, Tomas Marques-Bonet, Enrico Cappellini
Creator:        AH XSL Formatter V6.3 R1 for Linux64 : 6.3.1.23495 (2016/02/03 14:39JST)
Producer:       Antenna House PDF Output Library 6.3.752 (Linux64)
CreationDate:   Sat Dec 14 06:22:14 2019 CET
ModDate:        Sat Dec 14 06:22:14 2019 CET
Tagged:         yes
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          27
Encrypted:      no
Page size:      612 x 792 pts (letter)
Page rot:       0
File size:      3057028 bytes
Optimized:      no
PDF version:    1.5

name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
Times-Roman                          Type 1            Custom           no  no  yes     11  0
Helvetica-Bold                       Type 1            Custom           no  no  yes     13  0
Helvetica                            Type 1            Custom           no  no  yes     16  0
JXFNCS+Code2000                      CID TrueType      Identity-H       yes yes yes    206  0
Helvetica-BoldOblique                Type 1            Standard         no  no  no     322  0
Times-Bold                           Type 1            Standard         no  no  no     327  0
Times-BoldItalic                     Type 1            Standard         no  no  no     475  0

Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2020-08-10 12:18:48 CEST
 RepresentationInformation: pmc_31723270.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2020-07-06 04:06:36 CEST
  Size: 3057028
  Format: PDF
  Version: 1.5
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 0
   FreeObjects: 84
   IncrementalUpdates: 0
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: true
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: EN
    Outlines: 
     Item: 
      Title: Abstract
     Item: 
      Title: METHODS
      Children: 
       Item: 
        Title: CHUIFENG CAVE
       Item: 
        Title: THERMAL AGE
       Item: 
        Title: PROTEIN EXTRACTION
       Item: 
        Title: LC-MS/MS ANALYSIS
       Item: 
        Title: DATABASE CONSTRUCTION
        Children: 
         Item: 
          Title: Ancestral Sequence Reconstruction
       Item: 
        Title: Isoform variation
       Item: 
        Title: PROTEOMIC DATA ANALYSIS
       Item: 
        Title: PHYLOGENETIC and DIVERGENCE ANALYSIS
        Children: 
         Item: 
          Title: Comparative reference dataset
         Item: 
          Title: Reconstruction of protein sequences from whole-genome sequencing data
         Item: 
          Title: Assessing the phylogenetic position of Gigantopithecus blacki
          Children: 
           Item: 
            Title: Maximum-likelihood approach.
           Item: 
            Title: Bayesian approach.
         Item: 
          Title: Divergence time of Gigantopithecus
     Item: 
      Title: DATA AVAILABILITY
     Item: 
      Title: Extended Data
     Item: 
      Title: Extended Data Figure 1.
     Item: 
      Title: Extended Data Figure 2.
     Item: 
      Title: Extended Data Figure 3.
     Item: 
      Title: Extended Data Figure 4.
     Item: 
      Title: Extended Data Figure 5.
     Item: 
      Title: Extended Data Figure 6.
     Item: 
      Title: Extended Data Figure 7.
     Item: 
      Title: Extended Data Figure 8.
     Item: 
      Title: Extended Data Table 1.
     Item: 
      Title: Extended Data Table 2.
     Item: 
      Title: References
     Item: 
      Title: Figure 1.
     Item: 
      Title: Figure 2.
     Item: 
      Title: Figure 3.
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 152
      ImageHeight: 152
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1500
      ImageHeight: 1865
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1556
      ImageHeight: 2073
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1568
      ImageHeight: 1859
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 975
      ImageHeight: 1500
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1500
      ImageHeight: 1320
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1828
      ImageHeight: 1642
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1560
      ImageHeight: 1883
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1568
      ImageHeight: 1624
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2050
      ImageHeight: 1365
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 1218
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1500
      ImageHeight: 1337
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type0: 
     Font: 
      BaseFont: JXFNCS+Code2000
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: Helvetica
      FirstChar: 32
      LastChar: 131
      FontDescriptor: 
       FontName: Helvetica
       Flags: Nonsymbolic
       FontBBox: -166, -225, 1000, 931
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: Helvetica-BoldOblique
     Font: 
      BaseFont: Times-Bold
     Font: 
      BaseFont: Times-Roman
      FirstChar: 32
      LastChar: 142
      FontDescriptor: 
       FontName: Times-Roman
       Flags: Nonsymbolic
       FontBBox: -168, -218, 1000, 898
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: Times-BoldItalic
     Font: 
      BaseFont: Helvetica-Bold
      FirstChar: 32
      LastChar: 130
      FontDescriptor: 
       FontName: Helvetica-Bold
       Flags: Nonsymbolic
       FontBBox: -170, -228, 1003, 962
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: JXFNCS+Code2000
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: JXFNCS+Code2000
       Flags: Symbolic
       FontBBox: -1111, -295, 2107, 977
       FontFile2: true
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 255, 190, 336, 198
       LastModified: D:20191214002214-05'00'
    Page: 
     Sequence: 2
    Page: 
     Sequence: 3
    Page: 
     Sequence: 4
    Page: 
     Sequence: 5
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 484, 424, 511, 434
       LastModified: D:20191214002215-05'00'
      Annotation: 
       Subtype: Link
       Rect: 150, 410, 421, 420
       LastModified: D:20191214002215-05'00'
    Page: 
     Sequence: 7
    Page: 
     Sequence: 8
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 308, 652, 473, 662
       LastModified: D:20191214002215-05'00'
      Annotation: 
       Subtype: Link
       Rect: 178, 624, 423, 634
       LastModified: D:20191214002215-05'00'
      Annotation: 
       Subtype: Link
       Rect: 153, 596, 441, 606
       LastModified: D:20191214002215-05'00'
      Annotation: 
       Subtype: Link
       Rect: 150, 582, 445, 592
       LastModified: D:20191214002215-05'00'
    Page: 
     Sequence: 10
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 203, 445, 381, 455
       LastModified: D:20191214002215-05'00'
    Page: 
     Sequence: 12
    Page: 
     Sequence: 13
    Page: 
     Sequence: 14
    Page: 
     Sequence: 15
    Page: 
     Sequence: 16
    Page: 
     Sequence: 17
    Page: 
     Sequence: 18
    Page: 
     Sequence: 19
    Page: 
     Sequence: 20
    Page: 
     Sequence: 21
    Page: 
     Sequence: 22
    Page: 
     Sequence: 23
    Page: 
     Sequence: 24
    Page: 
     Sequence: 25
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 399, 330, 507, 340
       LastModified: D:20191214002222-05'00'
    Page: 
     Sequence: 26
    Page: 
     Sequence: 27
  Checksum: be8abf0c
   Type: CRC32
  Checksum: 3ca10ea5ace89590d461cc6403bed0b0
   Type: MD5
  Checksum: b216fe656e4f1dffec91d3a3f10241b0b7708557
   Type: SHA-1