c2ba5b141c2b34148622edf9efbc40c5 pmc_31920626.pdf 58ff813fb9c16381ec3c217deb4a4c6f471a66bd pmc_31920626.pdf bd4b254d055b595916d6d063d46e73c955c0e46c3d19abd985ebbb219b8e77f2 pmc_31920626.pdf Title: Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain Subject: The formation of senile plaques through amyloid-β peptide (Aβ) aggregation is a hallmark of Alzheimer's disease (AD). Keywords: cerebral cortex lipidome, long-chain polyunsaturated fatty acids, docosahexaenoic acid, sphingolipids, ovarian hormones, synaptic proteins, amyloid, estradiol Author: Luis M. Garcia-Segura Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Tue Dec 17 12:30:14 2019 CET ModDate: Tue Dec 17 13:48:09 2019 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 2348933 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VIJFQW+MinionPro-Regular Type 1 Custom yes yes no 32 0 JDCJKD+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 33 0 ARPWFR+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 34 0 YQLHNJ+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 39 0 GZDLUX+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 40 0 JEXWOA+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 41 0 MISHUY+MTGU Type 1 Builtin yes yes no 42 0 DWSDUV+MTSYN Type 1 Builtin yes yes no 43 0 VXWSEY+RBLMI Type 1 Builtin yes yes no 181 0 CBDPDG+MinionPro-It Type 1 Custom yes yes no 256 0 QVJHWF+MinionPro-Bold Type 1 Custom yes yes no 257 0 WLTEQU+MTGUB Type 1 Builtin yes yes no 296 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-08-10 12:12:43 CEST RepresentationInformation: pmc_31920626.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-07-06 04:03:20 CEST Size: 2348933 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 972 FreeObjects: 8 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Animals and Husbandry Item: Title: Genotyping Item: Title: Ovariectomy and Estradiol Treatment Item: Title: Diets Item: Title: Tissue Processing and Sample Preparation Item: Title: Lipid Analysis Item: Title: Amyloid Aβ Measurement Item: Title: Western Blot Analysis Item: Title: Statistical Analysis Item: Title: Results Children: Item: Title: The Composition of the Diets Item: Title: Effect of the Different Diets on the Brain Lipidome of Female APP/PS1 Mouse According to Their Gonadal Status Item: Title: Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain Item: Title: The Effects of Interaction Between Different Dietary n-6/n-3 PUFA Ratios and n-3 LC-PUFA Content With Gonadal Status on the Expression of GFAP, Signaling Proteins and Synaptic Markers in the Cerebral Cortex of Female APP/PS1 Mouse Item: Title: Discussion Item: Title: Data Availability Statement Item: Title: Ethics Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Info: Title: Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain Author: Luis M. Garcia-Segura Subject: The formation of senile plaques through amyloid-β peptide (Aβ) aggregation is a hallmark of Alzheimer's disease (AD). Keywords: cerebral cortex lipidome, long-chain polyunsaturated fatty acids, docosahexaenoic acid, sphingolipids, ovarian hormones, synaptic proteins, amyloid, estradiol Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Tue Dec 17 13:00:14 CET 2019 ModDate: Tue Dec 17 14:18:09 CET 2019 ID: 0x27b356b8dffcf35c90f7d78fbe14dce8, 0x4910ddae4481a74191c8fa1e420bf4ad Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: VIJFQW+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: VIJFQW+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CBDPDG+MinionPro-It FontSubset: true FirstChar: 39 LastChar: 241 FontDescriptor: FontName: CBDPDG+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JDCJKD+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 40 LastChar: 150 FontDescriptor: FontName: JDCJKD+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: QVJHWF+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 150 FontDescriptor: FontName: QVJHWF+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ARPWFR+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 124 FontDescriptor: FontName: ARPWFR+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VXWSEY+RBLMI FontSubset: true FirstChar: 49 LastChar: 62 FontDescriptor: FontName: VXWSEY+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: YQLHNJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: YQLHNJ+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GZDLUX+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: GZDLUX+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WLTEQU+MTGUB FontSubset: true FirstChar: 98 LastChar: 98 FontDescriptor: FontName: WLTEQU+MTGUB Flags: Symbolic FontBBox: 0, -205, 879, 699 FontFile: true Font: BaseFont: JEXWOA+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 2 LastChar: 241 FontDescriptor: FontName: JEXWOA+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: MISHUY+MTGU FontSubset: true FirstChar: 97 LastChar: 109 FontDescriptor: FontName: MISHUY+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: DWSDUV+MTSYN FontSubset: true FirstChar: 0 LastChar: 48 FontDescriptor: FontName: DWSDUV+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true XMP: cerebral cortex lipidome, long-chain polyunsaturated fatty acids, docosahexaenoic acid, sphingolipids, ovarian hormones, synaptic proteins, amyloid, estradiol pdfTeX-1.40.15 1.5 application/pdf fnagi-11-00346.tex Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain The formation of senile plaques through amyloid-β peptide (Aβ) aggregation is a hallmark of Alzheimer's disease (AD). Luis M. Garcia-Segura Francisco G. 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