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Title:           Origin of tuberculosis in the Paleolithic predicts unprecedented population growth and female resistance
Subject:         Scientific Reports, doi:10.1038/s41598-019-56769-1
Keywords:        
Creator:         Springer
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     Item: 
      Title: Origin of tuberculosis in the Paleolithic predicts unprecedented population growth and female resistance
      Children: 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: The irruption of “modern” lineages caused a dramatic impact in the Paleolithic. 
         Item: 
          Title: Higher population growth in the Neolithic allows the persistence of “modern” lineages. 
         Item: 
          Title: “Modern” lineages are better able to persist in the population. 
         Item: 
          Title: Fast progression, immunity, latency and higher susceptibility in recovered subjects are required to maintain epidemics. 
         Item: 
          Title: Female resistance is key to understanding the co-evolution of MtbC and humans. 
         Item: 
          Title: “Modern” lineages replace “ancient” ones. 
       Item: 
        Title: Discussion
       Item: 
        Title: Methodology
        Children: 
         Item: 
          Title: Basic TB natural history compartmental model. 
         Item: 
          Title: TBOREX model. 
         Item: 
          Title: Assessment of uncertainty and sensitivity in the system. 
         Item: 
          Title: Coinfection model. 
         Item: 
          Title: Continuous and discrete resolution of the models. 
       Item: 
        Title: Acknowledgements
       Item: 
        Title: Figure 1 SEIR model.
       Item: 
        Title: Figure 2 Evolution of the population in the continuous model TBOREX.
       Item: 
        Title: Figure 3 End values in the continuous model TBOREX.
       Item: 
        Title: Figure 4 End values and clearance in the TBOREX model simulation.
       Item: 
        Title: Figure 5 Distribution of final incidence per 100.
       Item: 
        Title: Figure 6 Role of the female tolerance in the evolution of “Ancient” lineages in the Paleolithic.
       Item: 
        Title: Figure 7 Role of the female tolerance in the evolution of “Modern” lineages in the Neolithic.
       Item: 
        Title: Figure 8 Sensitivity analysis.
       Item: 
        Title: Figure 9 Natality and the evolution of total population.
       Item: 
        Title: Figure 10 The Coinfection model.
       Item: 
        Title: Figure 11 The replacement of “ancient” lineages by “modern” ones in a continuous coinfection model.
       Item: 
        Title: Figure 12 The replacement of “ancient” lineages by “modern” ones in a discrete coinfection model.
       Item: 
        Title: Table 1 Parameters and references.
       Item: 
        Title: Table 2 Sensitivity analysis.
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    Keywords: 
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Comment 
PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. 
Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. 

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The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. 
If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). 
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Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. 
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Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. 

Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” 
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                           <pdfaProperty:description>This element provides the url for an article or unit of content. 
The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. 
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
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AM = Accepted Manuscript
P = Proof
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CVoR = Corrected Version of Record
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  Checksum: 5e46a09d2933ec361c1748e730020b295cf6c4577a481dc87793c2b9b644868c
   Type: SHA-256