36e6a6fe8b1758cc219ce0caf8762d49 226199.pdf 2b9b203b66d7df7d49bb50a28bac6993b031c8a0 226199.pdf 19706751d199d5e27668c7a7021ffcbd4adffd86cb6b8e847bc26ae5cbe9868e 226199.pdf Title: Issues Impacting Adverse Event Frequency and Severity: Differences Between Randomized Phase 2 and Phase 3 Clinical Trials for Lasmiditan Subject: Headache 2020.60:576-588 Creator: Adobe InDesign CC 2015 (Windows) Producer: Adobe PDF Library 15.0; modified using iText 4.2.0 by 1T3XT CreationDate: Sat Feb 22 10:13:28 2020 CET ModDate: Thu Mar 10 12:59:50 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 274052 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ERIOTF+TimesNewRomanMTStd Type 1C Custom yes yes yes 12 0 KYETZT+TimesNewRomanMTStd-BoldIt Type 1C WinAnsi yes yes yes 53 0 OWERDL+TimesNewRomanMTStd-Bold Type 1C Custom yes yes yes 14 0 DQNDFH+TimesNewRomanMTStd-Italic Type 1C WinAnsi yes yes yes 13 0 DQNDFH+TimesNewRomanMTStd-Italic Type 1C WinAnsi yes yes yes 44 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-11 02:30:51 CET RepresentationInformation: 226199.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-03-10 13:00:44 CET Size: 274052 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseThumbs Language: en-US Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1312 ImageHeight: 1879 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: KYETZT+TimesNewRomanMTStd-BoldIt FontSubset: true FirstChar: 83 LastChar: 119 FontDescriptor: FontName: KYETZT+TimesNewRomanMTStd-BoldIt Flags: Serif, Nonsymbolic, Italic FontBBox: -266, -259, 1076, 942 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: ERIOTF+TimesNewRomanMTStd FontSubset: true FirstChar: 30 LastChar: 233 FontDescriptor: FontName: ERIOTF+TimesNewRomanMTStd Flags: Serif, Nonsymbolic FontBBox: -94, -241, 1006, 916 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: DQNDFH+TimesNewRomanMTStd-Italic FontSubset: true FirstChar: 32 LastChar: 151 FontDescriptor: FontName: DQNDFH+TimesNewRomanMTStd-Italic Flags: Serif, Nonsymbolic, Italic FontBBox: -271, -246, 1100, 904 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: OWERDL+TimesNewRomanMTStd-Bold FontSubset: true FirstChar: 30 LastChar: 242 FontDescriptor: FontName: OWERDL+TimesNewRomanMTStd-Bold Flags: Serif, Nonsymbolic FontBBox: -191, -241, 1065, 957 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: application/pdfdoi:10.1111/head.13731 10.1111/head.13731https://doi.org/10.1111/head.13731 2020-01-13trueheadachejournal.onlinelibrary.wiley.com10.1111/head.13731 headachejournal.onlinelibrary.wiley.comtrue10.1111/head.137312020-01-13 Pages: Page: Label: 576 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 240, 561, 240, 549 Annotation: Subtype: Link Rect: 421, 154, 521, 144 Annotation: Subtype: Link Rect: 268, 110, 478, 100 Annotation: Subtype: Link Rect: 519, 782, 595, 767 Page: Label: 577 Sequence: 2 Page: Label: 578 Sequence: 3 Page: Label: 579 Sequence: 4 Page: Label: 580 Sequence: 5 Page: Label: 581 Sequence: 6 Page: Label: 582 Sequence: 7 Page: Label: 583 Sequence: 8 Page: Label: 584 Sequence: 9 Page: Label: 585 Sequence: 10 Page: Label: 586 Sequence: 11 Page: Label: 587 Sequence: 12 Page: Label: 588 Sequence: 13 Checksum: a160b59b Type: CRC32 Checksum: 36e6a6fe8b1758cc219ce0caf8762d49 Type: MD5 Checksum: 2b9b203b66d7df7d49bb50a28bac6993b031c8a0 Type: SHA-1