0h
 A                  0   2   5 24 M
                                                                     B                             1.0




                                                                         Correlation coefficient
             20                      kDa                      2h
                                     37                       5h                                   0.8
Volume (%)

             15                                               24 h
                                                              HS                                   0.6
             10                      25
                                                                                                   0.4
             5                                                                                     0.2
             0                                                                                     0.0
              0.1               1           10               100                                      0.1   10   103   105
                                                 Size (nm)                                                       Time (µs)
 C                  T22-BAK-GFP-H6         T22-PUMA-GFP-H6                               T22-BAXPORO-GFP-H6