48edf4c39007f9416e8e74c776237f29 jouclimed_a2020v9n10p3343.pdf 0102c0534b436250897be18f6e598c66e96704b9 jouclimed_a2020v9n10p3343.pdf 6e563e4f6395b8ad131bedc453d78e4c927e37136f3db2c3d8217ddabc9f6550 jouclimed_a2020v9n10p3343.pdf Title: Inadequate Weight Gain According to the Institute of Medicine 2009 Guidelines in Women with Gestational Diabetes: Frequency, Clinical Predictors, and the Association with Pregnancy Outcomes Subject: Background: In the care of women with gestational diabetes mellitus (GDM), more attention is put on glycemic control than in factors such as gestational weight gain (GWG). We aimed to evaluate the rate of inadequate GWG in women with GDM, its clinical predictors and the association with pregnancy outcomes. Methods: Cohort retrospective analysis. Outcome variables: GWG according to Institute of Medicine 2009 and 18 pregnancy outcomes. Clinical characteristics were considered both as GWG predictors and as covariates in outcome prediction. Statistics: descriptive, multinomial and logistic regression. Results: We assessed 2842 women diagnosed with GDM in the 1985–2011 period. GWG was insufficient (iGWG) in 50.3%, adequate in 31.6% and excessive (eGWG) in 18.1%; length of follow-up for GDM was positively associated with iGWG. Overall pregnancy outcomes were satisfactory. GWG was associated with pregnancy-induced hypertension, preeclampsia, cesarean delivery and birthweight-related outcomes. Essentially, the direction of the association was towards a higher risk with eGWG and lower risk with iGWG (i.e., with Cesarean delivery and excessive growth). Conclusions: In this cohort of women with GDM, inadequate GWG was very common at the expense of iGWG. The associations with pregnancy outcomes were mainly towards a higher risk with eGWG and lower risk with iGWG. Keywords: gestational diabetes mellitus; Institute of Medicine; weight gain; length of follow-up; pregnancy outcome Author: Xinglei Xie, Jiaming Liu, Isabel Pujol, Alicia López, María José Martínez, Apolonia García-Patterson, Juan M. 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