e24935cdc4369b244a35aa3a545f00e8  236096.pdf
5fca3810dd6e3296378bf74b9de67f3a7321c810  236096.pdf
1efba598f9e378c8c6a94c89b98f2ee399563eabf13d589c1459adafc8f3da9c  236096.pdf

Title:          Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens
Creator:        QuarkXPress(R) 13.01
Producer:       QuarkXPress(R) 13.01
CreationDate:   Fri Mar 20 13:37:12 2020 CET
ModDate:        Fri Mar 20 13:37:17 2020 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          10
Encrypted:      no
Page size:      617.953 x 816.378 pts
Page rot:       0
File size:      2531709 bytes
Optimized:      no
PDF version:    1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
TMTLAT+LegacySans-Medium             Type 1C           Custom           yes yes no      93  0
ZBDLHH+Arial-BoldMT                  Type 1C           Custom           yes yes yes     94  0
YTEMBW+FranklinGothic-MediumItalic   Type 1C           Custom           yes yes no      95  0
BQGUKV+StempelSchneidler-Italic      Type 1C           Custom           yes yes no       8  0
GSPSLD+FranklinGothic-Demi           Type 1C           Custom           yes yes no       7  0
NCWZIY+FranklinGothic-Medium         Type 1C           Custom           yes yes yes      6  0
HEWESU+StempelSchneidler-Roman       Type 1C           Custom           yes yes no       9  0
MMTDZL+FranklinGothic-DemiItal       Type 1C           Custom           yes yes no      96  0
GYWTKI+FranklinGothic-BookCmprItal   Type 1C           Custom           yes yes no      97  0
ISDJMB+FranklinGothic-BookCmpr       Type 1C           Custom           yes yes no      98  0
GABSJB+ArialMT                       Type 1C           Custom           yes yes no      10  0
HNNJDR+FranklinGothic-BookCmprItal   Type 1C           Custom           yes yes no      99  0
XVZMKQ+FranklinGothic-DemiCnd        Type 1C           Custom           yes yes no      12  0
KSLVAF+FranklinGothic-Book           Type 1C           Custom           yes yes yes     29  0
KQJTXF+Symbol                        Type 1C           Custom           yes yes yes     11  0
CIOPSA+Arial-ItalicMT                Type 1C           Custom           yes yes no      15  0
GXWGLL+FranklinGothic-DemiCmpr       Type 1C           Custom           yes yes no      16  0
GYUGZA+FranklinGothic-MedCnd         Type 1C           Custom           yes yes no      17  0
RRGCZC+Arial-BoldMT                  Type 1C           Custom           yes yes no      18  0
ERXSFH+Cheltenham-Light              Type 1C           Custom           yes yes no      19  0
SSWHLC+Cheltenham-LightCond          Type 1C           Custom           yes yes no      20  0
ZWJCDN+Helvetica-Condensed-Bold      Type 1C           Custom           yes yes no      28  0
VJTIQD+FranklinGothic-BookItalic     Type 1C           Custom           yes yes no      33  0
HIARPM+FranklinGothic-BookItalic     Type 1C           Custom           yes yes no      38  0
ODNRHT+StempelSchneidler-BoldItalic  Type 1C           Custom           yes yes no      48  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2021-02-02 02:21:10 CET
 RepresentationInformation: 236096.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2021-01-28 08:34:30 CET
  Size: 2531709
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 148
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
   Info: 
    Title: Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens
    Creator: QuarkXPress(R) 13.01
    Producer: QuarkXPress(R) 13.01
    CreationDate: Fri Mar 20 13:37:12 CET 2020
    ModDate: Fri Mar 20 13:37:17 CET 2020
   ID: 0x6f184bc8ae86416e85934939a17a5942, 0xe62eb2c4b59e44c1b3aecd5ede2a622b
   Filters: 
    FilterPipeline: FlateDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 403
      ImageHeight: 141
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 286
      ImageHeight: 352
      BitsPerSample: 4
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1772
      ImageHeight: 1123
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1772
      ImageHeight: 1199
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1772
      ImageHeight: 599
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1772
      ImageHeight: 613
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1772
      ImageHeight: 1244
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1772
      ImageHeight: 729
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      Name: F21
      BaseFont: NCWZIY+FranklinGothic-Medium
      FontSubset: true
      FirstChar: 1
      LastChar: 90
      FontDescriptor: 
       FontName: NCWZIY+FranklinGothic-Medium
       Flags: Symbolic
       FontBBox: -215, -307, 1093, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
      ToUnicode: true
     Font: 
      Name: F19
      BaseFont: GSPSLD+FranklinGothic-Demi
      FontSubset: true
      FirstChar: 1
      LastChar: 65
      FontDescriptor: 
       FontName: GSPSLD+FranklinGothic-Demi
       Flags: Nonsymbolic, ForceBold
       FontBBox: -199, -250, 1014, 934
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F8
      BaseFont: BQGUKV+StempelSchneidler-Italic
      FontSubset: true
      FirstChar: 1
      LastChar: 90
      FontDescriptor: 
       FontName: BQGUKV+StempelSchneidler-Italic
       Flags: Nonsymbolic, Italic
       FontBBox: -152, -265, 1122, 923
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F7
      BaseFont: HEWESU+StempelSchneidler-Roman
      FontSubset: true
      FirstChar: 0
      LastChar: 120
      FontDescriptor: 
       FontName: HEWESU+StempelSchneidler-Roman
       Flags: Nonsymbolic
       FontBBox: -165, -278, 1104, 933
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F16
      BaseFont: GABSJB+ArialMT
      FontSubset: true
      FirstChar: 0
      LastChar: 70
      FontDescriptor: 
       FontName: GABSJB+ArialMT
       Flags: Nonsymbolic
       FontBBox: -665, -325, 2000, 1006
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F26
      BaseFont: KQJTXF+Symbol
      FontSubset: true
      FirstChar: 0
      LastChar: 15
      FontDescriptor: 
       FontName: KQJTXF+Symbol
       Flags: Symbolic
       FontBBox: -167, -299, 1063, 827
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
      ToUnicode: true
     Font: 
      Name: F14
      BaseFont: XVZMKQ+FranklinGothic-DemiCnd
      FontSubset: true
      FirstChar: 1
      LastChar: 74
      FontDescriptor: 
       FontName: XVZMKQ+FranklinGothic-DemiCnd
       Flags: Nonsymbolic, ForceBold
       FontBBox: -141, -250, 941, 903
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F31
      BaseFont: CIOPSA+Arial-ItalicMT
      FontSubset: true
      FirstChar: 0
      LastChar: 13
      FontDescriptor: 
       FontName: CIOPSA+Arial-ItalicMT
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -517, -325, 1359, 998
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F9
      BaseFont: GXWGLL+FranklinGothic-DemiCmpr
      FontSubset: true
      FirstChar: 0
      LastChar: 73
      FontDescriptor: 
       FontName: GXWGLL+FranklinGothic-DemiCmpr
       Flags: Serif, Nonsymbolic, ForceBold
       FontBBox: -104, -250, 744, 881
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F18
      BaseFont: GYUGZA+FranklinGothic-MedCnd
      FontSubset: true
      FirstChar: 0
      LastChar: 62
      FontDescriptor: 
       FontName: GYUGZA+FranklinGothic-MedCnd
       Flags: Serif, Nonsymbolic
       FontBBox: -156, -250, 945, 898
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F17
      BaseFont: RRGCZC+Arial-BoldMT
      FontSubset: true
      FirstChar: 0
      LastChar: 52
      FontDescriptor: 
       FontName: RRGCZC+Arial-BoldMT
       Flags: Serif, Nonsymbolic, ForceBold
       FontBBox: -628, -376, 2000, 1018
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F3
      BaseFont: ERXSFH+Cheltenham-Light
      FontSubset: true
      FirstChar: 0
      LastChar: 70
      FontDescriptor: 
       FontName: ERXSFH+Cheltenham-Light
       Flags: Serif, Nonsymbolic
       FontBBox: -126, -221, 1038, 923
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F12
      BaseFont: SSWHLC+Cheltenham-LightCond
      FontSubset: true
      FirstChar: 0
      LastChar: 88
      FontDescriptor: 
       FontName: SSWHLC+Cheltenham-LightCond
       Flags: Nonsymbolic
       FontBBox: -167, -214, 1000, 934
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F35
      BaseFont: ZWJCDN+Helvetica-Condensed-Bold
      FontSubset: true
      FirstChar: 0
      LastChar: 23
      FontDescriptor: 
       FontName: ZWJCDN+Helvetica-Condensed-Bold
       Flags: Serif, Nonsymbolic, ForceBold
       FontBBox: -169, -250, 1091, 991
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F10
      BaseFont: KSLVAF+FranklinGothic-Book
      FontSubset: true
      FirstChar: 1
      LastChar: 114
      FontDescriptor: 
       FontName: KSLVAF+FranklinGothic-Book
       Flags: Symbolic
       FontBBox: -192, -331, 1024, 954
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
      ToUnicode: true
     Font: 
      Name: F29
      BaseFont: TMTLAT+LegacySans-Medium
      FontSubset: true
      FirstChar: 0
      LastChar: 11
      FontDescriptor: 
       FontName: TMTLAT+LegacySans-Medium
       Flags: Serif, Nonsymbolic
       FontBBox: -208, -271, 1055, 884
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F28
      BaseFont: ZBDLHH+Arial-BoldMT
      FontSubset: true
      FirstChar: 0
      LastChar: 24
      FontDescriptor: 
       FontName: ZBDLHH+Arial-BoldMT
       Flags: Symbolic, ForceBold
       FontBBox: -628, -376, 2000, 1018
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
      ToUnicode: true
     Font: 
      Name: F22
      BaseFont: YTEMBW+FranklinGothic-MediumItalic
      FontSubset: true
      FirstChar: 1
      LastChar: 61
      FontDescriptor: 
       FontName: YTEMBW+FranklinGothic-MediumItalic
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -160, -307, 1047, 951
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F20
      BaseFont: MMTDZL+FranklinGothic-DemiItal
      FontSubset: true
      FirstChar: 0
      LastChar: 45
      FontDescriptor: 
       FontName: MMTDZL+FranklinGothic-DemiItal
       Flags: Serif, Nonsymbolic, Italic, ForceBold
       FontBBox: -200, -250, 1177, 892
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F6
      BaseFont: GYWTKI+FranklinGothic-BookCmprItal
      FontSubset: true
      FirstChar: 1
      LastChar: 64
      FontDescriptor: 
       FontName: GYWTKI+FranklinGothic-BookCmprItal
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -175, -250, 818, 875
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F11
      BaseFont: VJTIQD+FranklinGothic-BookItalic
      FontSubset: true
      FirstChar: 1
      LastChar: 70
      FontDescriptor: 
       FontName: VJTIQD+FranklinGothic-BookItalic
       Flags: Nonsymbolic, Italic
       FontBBox: -225, -331, 1085, 960
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F5
      BaseFont: ISDJMB+FranklinGothic-BookCmpr
      FontSubset: true
      FirstChar: 1
      LastChar: 65
      FontDescriptor: 
       FontName: ISDJMB+FranklinGothic-BookCmpr
       Flags: Serif, Nonsymbolic
       FontBBox: -120, -250, 771, 877
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F4
      BaseFont: HNNJDR+FranklinGothic-BookCmprItal
      FontSubset: true
      FirstChar: 0
      LastChar: 43
      FontDescriptor: 
       FontName: HNNJDR+FranklinGothic-BookCmprItal
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -175, -250, 818, 875
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F42
      BaseFont: HIARPM+FranklinGothic-BookItalic
      FontSubset: true
      FirstChar: 0
      LastChar: 0
      FontDescriptor: 
       FontName: HIARPM+FranklinGothic-BookItalic
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -225, -331, 1085, 960
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
     Font: 
      Name: F25
      BaseFont: ODNRHT+StempelSchneidler-BoldItalic
      FontSubset: true
      FirstChar: 0
      LastChar: 16
      FontDescriptor: 
       FontName: ODNRHT+StempelSchneidler-BoldItalic
       Flags: Serif, Nonsymbolic, Italic, ForceBold
       FontBBox: -179, -265, 1144, 953
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: MacRomanEncoding
       Differences: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.2-c001 63.139439, 2010/09/27-13:37:26        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:ModifyDate>2020-03-20T13:37:17+01:00</xmp:ModifyDate>
         <xmp:CreateDate>2020-03-20T13:37:12+01:00</xmp:CreateDate>
         <xmp:MetadataDate>2020-03-20T13:37:17+01:00</xmp:MetadataDate>
         <xmp:CreatorTool>QuarkXPress(R) 13.01</xmp:CreatorTool>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">2009</rdf:li>
            </rdf:Alt>
         </dc:title>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:a84beaae-fff3-4f48-8154-389f48e3eed1</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:3f6a276e-ad91-374d-b46a-cb4037337ebc</xmpMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>QuarkXPress(R) 13.01</pdf:Producer>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
    Page: 
     Sequence: 2
    Page: 
     Sequence: 3
    Page: 
     Sequence: 4
    Page: 
     Sequence: 5
    Page: 
     Sequence: 6
    Page: 
     Sequence: 7
    Page: 
     Sequence: 8
    Page: 
     Sequence: 9
    Page: 
     Sequence: 10
  Checksum: 74d938b9
   Type: CRC32
  Checksum: e24935cdc4369b244a35aa3a545f00e8
   Type: MD5
  Checksum: 5fca3810dd6e3296378bf74b9de67f3a7321c810
   Type: SHA-1