607f06a5583e558af9ed14f2257e12f6 236426.pdf 879754c3584543f0811c5f9bbeb16ea2427e3975 236426.pdf cf207eda3a416f91927c4f632670a3ee3bf3395153d2e7383c549f4b1e5d686e 236426.pdf Title: Point-Of-Care CAR T-Cell Production (ARI-0001) Using a Closed Semi-automatic Bioreactor: Experience From an Academic Phase I Clinical Trial Subject: Development of semi-automated devices that can reduce the hands-on time and standardize the production of clinical-grade CAR T-cells, such as CliniMACS Prodigy from Miltenyi, is key to facilitate the development of CAR T-cell therapies, especially in academic institutions. Keywords: chimeric antigen receptor, CD19, leukemia, lymphoma, immunotherapy, CAR T-cell production, CliniMACS Prodigy Author: Maria Castella and Manel Juan Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Fri Mar 20 07:57:58 2020 CET ModDate: Fri Mar 20 08:41:21 2020 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 1101638 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DVGEPL+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 62 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 60 0 DREXAI+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 43 0 DEFVXD+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 38 0 WGAFBJ+MTSY Type 1C Custom yes yes yes 82 0 SVCHIA+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 69 0 HDOCLA+MTGU Type 1C Custom yes yes no 98 0 LQMWXP+MinionPro-It Type 1C WinAnsi yes yes no 94 0 ZFIZIX+MinionPro-Regular Type 1C Custom yes yes no 92 0 MRYYUU+MinionPro-Bold Type 1C Custom yes yes no 126 0 CVJJBP+RMTMI Type 1C Custom yes yes yes 156 0 KLQVAA+MTSYB Type 1C Custom yes yes no 151 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-02-09 02:23:56 CET RepresentationInformation: 236426.pdf ReportingModule: BYTESTREAM, Rel. 1.4 (2018-10-01) LastModified: 2021-02-06 08:21:23 CET Size: 1101638 Format: bytestream Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/octet-stream Checksum: ba40dcb8 Type: CRC32 Checksum: 607f06a5583e558af9ed14f2257e12f6 Type: MD5 Checksum: 879754c3584543f0811c5f9bbeb16ea2427e3975 Type: SHA-1