685b9c3f2f799715dfa63c05428597e0 236625.pdf 38c46fcfa47bd4e3d9b55350f57054c978f7edb1 236625.pdf bb5b0d5d11990ed7e36d8ee07c70c30d69dde927c055555ba52eb1ae1463e722 236625.pdf Title: Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS Subject: Leukemia, doi:10.1038/s41375-020-0917-7 Keywords: Author: A. Kuendgen Creator: Springer CreationDate: Wed Jun 24 18:27:52 2020 CEST ModDate: Wed Jun 24 18:28:44 2020 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 15 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 3565601 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MLHDCA+AdvOT5fcf1b24 Type 1C WinAnsi yes yes no 744 0 MLHIOG+AdvOTb4af3d5d.I Type 1C WinAnsi yes yes no 776 0 MLHIPG+AdvTT4ff65459 Type 1C WinAnsi yes yes no 779 0 MLHIPH+AdvOT9d60b855.B Type 1C WinAnsi yes yes no 780 0 MLHDDB+AdvOTce3d9a73 Type 1C WinAnsi yes yes no 742 0 MLHEMI+AdvOTc20ddc96 Type 1C WinAnsi yes yes no 755 0 MLHEMJ+AdvOTc20ddc96+fb Type 1C Custom yes yes yes 756 0 MLHEMK+AdvOTc20ddc96+20 Type 1C WinAnsi yes yes no 757 0 MLHFCJ+AdvOT8608a8d1+25 Type 1C Custom yes yes yes 758 0 MLHIOD+AdvOT3b30f6db.B Type 1C WinAnsi yes yes no 766 0 MLHIOE+AdvOTf9433e2d Type 1C WinAnsi yes yes no 767 0 MLHIOF+AdvOTf9433e2d+fb Type 1C Custom yes yes yes 772 0 MLHJBI+AdvOTf9433e2d+20 Type 1C WinAnsi yes yes no 338 0 MLHJCI+AdvTTab7e17fd+22 Type 1C Custom yes yes no 333 0 MLHJEI+AdvOT35387326.B Type 1C WinAnsi yes yes no 350 0 MLHJEJ+AdvOTf9433e2d+22 Type 1C Custom yes yes yes 349 0 MLHJFK+AdvTTab7e17fd Type 1C WinAnsi yes yes no 358 0 MLHJFL+AdvOT5fcf1b24+fb Type 1C Custom yes yes yes 344 0 MLHJHL+AdvOT35387326.B+fb Type 1C Custom yes yes yes 359 0 MLJLJL+AdvOT9d60b855.B+fb Type 1C Custom yes yes yes 375 0 MMBFGA+AdvOT3b30f6db.B+fb Type 1C Custom yes yes yes 452 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-02-17 02:20:16 CET RepresentationInformation: 236625.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-02-11 19:47:46 CET Size: 3565601 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR5' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR26' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR27' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR28' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR29' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR30' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR33' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR33' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR33' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR38' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR39' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR40' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR44' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR45' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR49' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR50' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR42' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR51' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR52' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR53' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR56' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR57' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR57' cannot be found Offset: 3513918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR57' cannot be found Offset: 3513918 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 864 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach t漀 挀氀愀猀猀椀昀椀挀愀琀椀漀渀 漀昀 瀀愀琀椀攀渀琀猀 眀椀琀栀 琀ⴀ䴀䐀匩㸾൥湤潢樍㠵㈠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀ㄩ⽆‰⽎數琠㠶㈠〠刯偡牥湴‸㔱‰⁒⽔楴汥⣾＀䄀戀猀琀爀愀挀琩㸾൥湤潢樍㠵㌠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀㜩⽆‰⽐慲敮琠㠵ㄠ〠刯偲敶‸㔴‰⁒⽔楴汥⣾＀䄀㜩㸾൥湤潢樍㠵㐠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀㘩⽆‰⽎數琠㠵㌠〠刯偡牥湴‸㔱‰⁒⽐牥瘠㠵㔠〠刯呩瑬攨References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Children: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Material and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Children: Item: Title: Patient characteristics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Application of classification and prognostic scoring systems Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Children: Item: Title: Compliance with ethical standards Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: ACKNOWLEDGMENTS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: A7 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Info: Title: Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS Author: A. Kuendgen Subject: Leukemia, doi:10.1038/s41375-020-0917-7 Keywords: Creator: Springer CreationDate: Wed Jun 24 18:57:52 CEST 2020 ModDate: Wed Jun 24 18:58:44 CEST 2020 ID: 0x157a086c9eda213cf89b156fe4dfc299, 0x88d259dd51b6b745bda2d20b938948c6 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 96 ImageHeight: 82 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1750 ImageHeight: 1978 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1800 ImageHeight: 2029 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1750 ImageHeight: 2025 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1950 ImageHeight: 606 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1325 ImageHeight: 1263 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: MLHIOF+AdvOTf9433e2d+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: MLHIOF+AdvOTf9433e2d+fb Flags: Symbolic FontBBox: 0, 0, 520, 697 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MMBFGA+AdvOT3b30f6db.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: MMBFGA+AdvOT3b30f6db.B+fb Flags: Symbolic FontBBox: 0, 0, 833, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLHDDB+AdvOTce3d9a73 FontSubset: true FirstChar: 44 LastChar: 252 FontDescriptor: FontName: MLHDDB+AdvOTce3d9a73 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHJFK+AdvTTab7e17fd FontSubset: true FirstChar: 43 LastChar: 61 FontDescriptor: FontName: MLHJFK+AdvTTab7e17fd Flags: Nonsymbolic FontBBox: -156, -250, 1072, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHJHL+AdvOT35387326.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: MLHJHL+AdvOT35387326.B+fb Flags: Symbolic FontBBox: 0, 0, 791, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLHIOG+AdvOTb4af3d5d.I FontSubset: true FirstChar: 51 LastChar: 116 FontDescriptor: FontName: MLHIOG+AdvOTb4af3d5d.I Flags: Nonsymbolic FontBBox: -166, -208, 906, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHDCA+AdvOT5fcf1b24 FontSubset: true FirstChar: 40 LastChar: 169 FontDescriptor: FontName: MLHDCA+AdvOT5fcf1b24 Flags: Nonsymbolic FontBBox: -31, -250, 770, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHIPG+AdvTT4ff65459 FontSubset: true FirstChar: 42 LastChar: 42 FontDescriptor: FontName: MLHIPG+AdvTT4ff65459 Flags: Nonsymbolic FontBBox: 0, -208, 1354, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHIPH+AdvOT9d60b855.B FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: MLHIPH+AdvOT9d60b855.B Flags: Serif, Nonsymbolic FontBBox: -62, -208, 979, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHJCI+AdvTTab7e17fd+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: MLHJCI+AdvTTab7e17fd+22 Flags: Nonsymbolic FontBBox: -156, -218, 937, 947 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MLHJBI+AdvOTf9433e2d+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: MLHJBI+AdvOTf9433e2d+20 Flags: Nonsymbolic FontBBox: -166, -145, 1000, 708 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHEMI+AdvOTc20ddc96 FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: MLHEMI+AdvOTc20ddc96 Flags: Nonsymbolic FontBBox: -31, -250, 791, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHEMJ+AdvOTc20ddc96+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: MLHEMJ+AdvOTc20ddc96+fb Flags: Symbolic FontBBox: 0, 0, 750, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLHEMK+AdvOTc20ddc96+20 FontSubset: true FirstChar: 146 LastChar: 151 FontDescriptor: FontName: MLHEMK+AdvOTc20ddc96+20 Flags: Nonsymbolic FontBBox: -125, -197, 1114, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHFCJ+AdvOT8608a8d1+25 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: MLHFCJ+AdvOT8608a8d1+25 Flags: Symbolic FontBBox: -10, -302, 1208, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLJLJL+AdvOT9d60b855.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: MLJLJL+AdvOT9d60b855.B+fb Flags: Symbolic FontBBox: 0, 0, 531, 697 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLHJFL+AdvOT5fcf1b24+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: MLHJFL+AdvOT5fcf1b24+fb Flags: Symbolic FontBBox: 0, 0, 687, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLHJEJ+AdvOTf9433e2d+22 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: MLHJEJ+AdvOTf9433e2d+22 Flags: Symbolic FontBBox: -166, -187, 645, 854 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MLHIOD+AdvOT3b30f6db.B FontSubset: true FirstChar: 65 LastChar: 117 FontDescriptor: FontName: MLHIOD+AdvOT3b30f6db.B Flags: Nonsymbolic FontBBox: -31, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHJEI+AdvOT35387326.B FontSubset: true FirstChar: 65 LastChar: 121 FontDescriptor: FontName: MLHJEI+AdvOT35387326.B Flags: Nonsymbolic FontBBox: -31, -250, 802, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MLHIOE+AdvOTf9433e2d FontSubset: true FirstChar: 35 LastChar: 248 FontDescriptor: FontName: MLHIOE+AdvOTf9433e2d Flags: Serif, Nonsymbolic FontBBox: -62, -208, 927, 895 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1038/s41375-020-0917-7 Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS A. Kuendgen M. Nomdedeu H. Tuechler G. Garcia-Manero R. S. Komrokji M. A. Sekeres M. G. Porta M. Cazzola A. E. DeZern G. J. Roboz D. P. Steensma A. A. Loosdrecht R. F. Schlenk J. Grau X. Calvo S. Blum A. Pereira P. Valent D. Costa A. Giagounidis B. Xicoy H. Döhner U. Platzbecker C. Pedro M. Lübbert I. Oiartzabal M. Díez-Campelo M. T. Cedena S. Machherndl-Spandl M. López-Pavía C. D. Baldus M. Martinez-de-Sola R. Stauder B. Merchan A. List C. Ganster T. Schroeder M. T. Voso M. Pfeilstöcker H. Sill B. Hildebrandt J. Esteve B. Nomdedeu F. Cobo R. Haas F. Sole U. Germing P. L. Greenberg D. Haase G. Sanz Springer US Leukemia, doi:10.1038/s41375-020-0917-7 10.1038/s41375-020-0917-7 http://dx.doi.org/10.1038/s41375-020-0917-7 journal Leukemia © 2020, The Author(s) 1476-5551 10.1038/s41375-020-0917-7 springer.com springerlink.com 2010-04-23 True 10.1038/s41375-020-0917-7 springer.com springerlink.com Springer 2020-06-24T21:58:44+05:30 2020-06-24T21:57:52+05:30 2020-06-24T21:58:44+05:30 True VoR uuid:482e9799-589f-4591-9d8d-553e17f2a4e6 uuid:ab439acb-0f83-464e-a40a-97d9fda98649 default 1 converted uuid:fefa7baa-de2f-4f02-858e-794af34ebb27 converted to PDF/A-2b pdfToolbox 2020-06-24T21:58:44+05:30 2 B A. Kuendgen http://orcid.org/0000-0002-1833-1890 H. Tuechler http://orcid.org/0000-0002-1568-3436 M. Cazzola http://orcid.org/0000-0001-6984-8817 D. P. Steensma http://orcid.org/0000-0001-5130-9284 R. F. Schlenk http://orcid.org/0000-0003-2215-2059 X. Calvo http://orcid.org/0000-0001-7934-9130 S. Blum http://orcid.org/0000-0003-2275-3081 C. Ganster http://orcid.org/0000-0002-7566-5985 M. T. Voso http://orcid.org/0000-0002-6164-4761 G. Sanz http://orcid.org/0000-0002-2767-8191 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://crossref.org/crossmark/1.0/ crossmark crossmark internal CrossMarkDomains CrossMarkDomains Seq Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Usual same as prism:doi DOI Text external The date when a publication was published. MajorVersionDate Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Copyright copyright Text external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. issn Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url Text http://springernature.com/ns/xmpExtensions/2.0/ sn Springer Nature ORCID Schema external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. authorInfo Bag AuthorInformation Specifies the types of author information: name and ORCID of an author. http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author AuthorInformation Gives the name of an author. name Text Gives the ORCID of an author. orcid URI http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 515, 694, 517, 721 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 515, 698, 534, 725 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 534, 715, 544, 725 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 107, 604, 108, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 107, 604, 108, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 117, 604, 117, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 108, 604, 117, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 117, 604, 117, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 252, 604, 253, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 252, 604, 253, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 262, 604, 263, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 253, 604, 262, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 262, 604, 262, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 183, 592, 184, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 183, 592, 184, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 193, 592, 194, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 184, 592, 193, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 193, 592, 193, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 400, 592, 401, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 400, 592, 401, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 410, 592, 411, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 401, 592, 410, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 410, 592, 410, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 105, 580, 106, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 105, 580, 106, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 115, 580, 116, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 106, 580, 115, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 115, 580, 115, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 224, 580, 225, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 224, 580, 225, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 234, 580, 235, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 225, 580, 234, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 234, 580, 234, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 580, 283, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 580, 283, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 292, 580, 293, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 283, 580, 292, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 292, 580, 292, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 195, 542, 196, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 195, 542, 196, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 204, 542, 205, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 196, 542, 204, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 204, 542, 204, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 328, 542, 329, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 328, 542, 329, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 542, 339, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 330, 542, 338, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 542, 338, 552 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 83, 517, 84, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 83, 517, 84, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 93, 517, 94, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 84, 517, 93, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 93, 517, 93, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 374, 186, 379, 196 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 384, 186, 389, 196 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 421, 174, 426, 184 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 506, 174, 511, 184 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 440, 161, 445, 171 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 450, 161, 455, 171 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 65, 89, 184, 98 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 265, 138, 289, 147 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 51, 128, 173, 137 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 221, 722, 226, 732 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 278, 709, 283, 719 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 101, 597, 106, 607 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 112, 597, 117, 607 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 184, 510, 189, 520 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 194, 510, 199, 520 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 278, 498, 283, 508 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 182, 448, 187, 458 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 192, 448, 202, 458 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 54, 435, 64, 445 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 69, 435, 79, 445 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 149, 423, 159, 433 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 164, 423, 174, 433 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 120, 373, 130, 383 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 431, 659, 436, 669 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 441, 659, 446, 669 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 454, 659, 464, 669 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 473, 659, 483, 669 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 344, 473, 354, 483 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 354, 336, 364, 346 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 231, 659, 241, 669 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 247, 659, 257, 669 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 76, 385, 81, 395 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 172, 311, 177, 321 Flags: Print AppearanceDictionary: true Destination: 31 Thumb: true Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 333, 199, 338, 209 Flags: Print AppearanceDictionary: true Destination: 54 Thumb: true Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 158, 373, 163, 383 Flags: Print AppearanceDictionary: true Destination: 71 Annotation: Subtype: Link Rect: 165, 298, 170, 308 Flags: Print AppearanceDictionary: true Destination: 71 Annotation: Subtype: Link Rect: 194, 112, 199, 122 Flags: Print AppearanceDictionary: true Destination: 71 Annotation: Subtype: Link Rect: 432, 684, 437, 694 Flags: Print AppearanceDictionary: true Destination: 71 Annotation: Subtype: Link Rect: 381, 560, 386, 570 Flags: Print AppearanceDictionary: true Destination: 85 Annotation: Subtype: Link Rect: 344, 373, 349, 383 Flags: Print AppearanceDictionary: true Destination: 98 Annotation: Subtype: Link Rect: 486, 161, 491, 171 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 498, 161, 503, 171 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 396, 124, 401, 134 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 410, 124, 414, 134 Flags: Print AppearanceDictionary: true Destination: 181 Thumb: true Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 217, 174, 227, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 229, 149, 239, 159 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 158, 136, 168, 146 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 497, 87, 502, 97 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 510, 87, 520, 97 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 528, 87, 538, 97 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 174, 124, 184, 134 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 189, 124, 199, 134 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 205, 124, 215, 134 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 507, 174, 512, 184 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 519, 174, 524, 184 Flags: Print AppearanceDictionary: true Destination: 181 Thumb: true Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 171, 87, 181, 97 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 391, 161, 396, 171 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 401, 161, 411, 171 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 416, 161, 426, 171 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 350, 112, 355, 122 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 361, 112, 371, 122 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 376, 112, 386, 122 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 167, 448, 177, 458 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 183, 448, 193, 458 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 199, 448, 209, 458 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 179, 248, 189, 258 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 197, 248, 207, 258 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 54, 174, 64, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 70, 174, 80, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 86, 174, 96, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 102, 174, 112, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 118, 174, 128, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 328, 659, 333, 669 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 353, 659, 359, 669 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 499, 585, 504, 595 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 325, 485, 330, 495 Flags: Print AppearanceDictionary: true Destination: 161 Annotation: Subtype: Link Rect: 402, 361, 406, 371 Flags: Print AppearanceDictionary: true Destination: 31 Annotation: Subtype: Link Rect: 341, 298, 351, 308 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 309, 248, 319, 258 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 382, 199, 392, 209 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 398, 199, 408, 209 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 413, 199, 423, 209 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 452, 174, 462, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 467, 174, 477, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 428, 161, 438, 171 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 448, 74, 458, 84 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 465, 74, 475, 84 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 482, 74, 492, 84 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 500, 74, 510, 84 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 88, 87, 98, 97 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 309, 136, 319, 146 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 327, 136, 337, 146 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 498, 74, 508, 84 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 514, 74, 524, 84 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 54, 273, 59, 283 Flags: Print AppearanceDictionary: true Destination: 181 Annotation: Subtype: Link Rect: 65, 273, 75, 283 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 81, 273, 92, 283 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 97, 273, 108, 283 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 114, 273, 124, 283 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 129, 273, 139, 283 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 89, 236, 100, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 272, 149, 283, 159 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 132, 87, 142, 97 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 248, 637, 289, 646 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 51, 627, 108, 636 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 207, 396, 289, 405 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 51, 386, 116, 395 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 381, 543, 527, 551 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 382, 513, 533, 521 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 13 Annotations: Annotation: Subtype: Link Rect: 117, 593, 208, 601 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 87, 573, 241, 581 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 484, 672, 544, 681 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 320, 662, 417, 671 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 14 Annotations: Annotation: Subtype: Link Rect: 107, 697, 108, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 107, 697, 108, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 117, 697, 117, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 108, 697, 117, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 117, 697, 117, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 252, 697, 253, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 252, 697, 253, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 262, 697, 263, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 253, 697, 262, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 262, 697, 262, 707 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 183, 684, 184, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 183, 684, 184, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 193, 684, 194, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 184, 684, 193, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 193, 684, 193, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 400, 684, 401, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 400, 684, 401, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 410, 684, 411, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 401, 684, 410, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 410, 684, 410, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 105, 672, 106, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 105, 672, 106, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 115, 672, 116, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 106, 672, 115, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 115, 672, 115, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 224, 672, 225, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 224, 672, 225, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 234, 672, 235, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 225, 672, 234, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 234, 672, 234, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 672, 283, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 672, 283, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 292, 672, 293, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 283, 672, 292, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 292, 672, 292, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 195, 635, 196, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 195, 635, 196, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 204, 635, 205, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 196, 635, 204, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 204, 635, 204, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 328, 635, 329, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 328, 635, 329, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 635, 339, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 330, 635, 338, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 635, 338, 644 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 83, 610, 84, 620 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 83, 610, 84, 620 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 93, 610, 94, 620 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 84, 610, 93, 620 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 93, 610, 93, 620 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 15 Thumb: true Checksum: 04c57c69 Type: CRC32 Checksum: 685b9c3f2f799715dfa63c05428597e0 Type: MD5 Checksum: 38c46fcfa47bd4e3d9b55350f57054c978f7edb1 Type: SHA-1