e58b8e3e9357c62657e3efa5299605dd 244141.pdf 0e72708ec1f0182b8d46a32f204765e1787f378b 244141.pdf 9cd5a973f7e10c3457125aa3cf6903eee13b442185f7df4a0371b918c59f7537 244141.pdf Title: Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19 Subject: Cardiovascular disease causes almost one third of deaths worldwide, and more than half are related to primary arterial hypertension (PAH). Keywords: primary arterial hypertension, angiotensin-converting enzyme 2, COVID-19, SARS-CoV2, endothelial dysfunction, renin–angiotensin–aldosterone system, oxidative and inflammatory stress, small resistance arteries" Author: Marı́a Galán and Francesc Jiménez-Altayó Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Sun Oct 25 14:46:29 2020 CET ModDate: Mon Oct 26 03:12:23 2020 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 539225 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 43 0 UHQXKJ+HelveticaNeueLTStd-LtIt Type 1C WinAnsi yes yes no 45 0 PKYMJF+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 51 0 AISTKX+MinionPro-Regular Type 1C Custom yes yes no 53 0 XTSMCO+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 25 0 EYXMYO+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 30 0 GBAUGV+RMTMI Type 1C WinAnsi yes yes no 68 0 RCUTOR+MTGU Type 1C Custom yes yes no 70 0 AORAKX+MTSY Type 1C Custom yes yes no 138 0 BSLQQC+MinionPro-It Type 1C Custom yes yes no 173 0 RCTMUC+MinionPro-Bold Type 1C Custom yes yes no 213 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-02-19 02:32:59 CET RepresentationInformation: 244141.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-02-18 18:00:14 CET Size: 539225 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 382 FreeObjects: 14 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Small Resistance Artery Disease in Hypertension: The Contribution of the RAS Pathway Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Hypertension, ACE2, and SARS-Cov2 Infection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Small Resistance Artery Disease and ACE2 in COVID-19-Related Vascular Pathology Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: Evidence of Hypertension-Like Small Resistance Artery Disease in COVID-19 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Potential Impact of SARS-CoV-2–Induced ``Cytokine Storm'' on Small Resistance Artery Properties Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Small Resistance Artery Disease and ACE2 in Vascular Pathology Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Conclusions and Upcoming Perspectives Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Info: Title: Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19 Author: Marı́a Galán and Francesc Jiménez-Altayó Subject: Cardiovascular disease causes almost one third of deaths worldwide, and more than half are related to primary arterial hypertension (PAH). Keywords: primary arterial hypertension, angiotensin-converting enzyme 2, COVID-19, SARS-CoV2, endothelial dysfunction, renin angiotensin aldosterone system, oxidative and inflammatory stress, small resistance arteries" Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Sun Oct 25 15:16:29 CET 2020 ModDate: Mon Oct 26 03:42:23 CET 2020 ID: 0x54f3730f92891180b5561bf9c5b5f2d0, 0x3aef389ff5b19c4abf600736de184877 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 279 ImageHeight: 279 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 1175 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: PKYMJF+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 243 FontDescriptor: FontName: PKYMJF+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -64, -205, 891, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GBAUGV+RMTMI FontSubset: true FirstChar: 60 LastChar: 60 FontDescriptor: FontName: GBAUGV+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 682, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AISTKX+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: AISTKX+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: RCTMUC+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: RCTMUC+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 660, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: RCUTOR+MTGU FontSubset: true FirstChar: 97 LastChar: 109 FontDescriptor: FontName: RCUTOR+MTGU Flags: Symbolic FontBBox: 0, -206, 607, 683 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: XTSMCO+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: XTSMCO+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -9, -214, 848, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: AORAKX+MTSY FontSubset: true FirstChar: 24 LastChar: 67 FontDescriptor: FontName: AORAKX+MTSY Flags: Symbolic FontBBox: 0, -83, 724, 583 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PIAOFJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PIAOFJ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: UHQXKJ+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: UHQXKJ+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 858, 729 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BSLQQC+MinionPro-It FontSubset: true FirstChar: 3 LastChar: 252 FontDescriptor: FontName: BSLQQC+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 903, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: EYXMYO+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 243 FontDescriptor: FontName: EYXMYO+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -30, -214, 773, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: 2020-10-25T19:16:29+05:30 LaTeX with hyperref package + hypdvips 2020-10-26T07:42:23+05:30 2020-10-26T07:42:23+05:30 application/pdf Cardiovascular disease causes almost one third of deaths worldwide, and more than half are related to primary arterial hypertension (PAH). Marı́a Galán and Francesc Jiménez-Altayó Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19 primary arterial hypertension angiotensin-converting enzyme 2 COVID-19 SARS-CoV2 endothelial dysfunction renin–angiotensin–aldosterone system oxidative and inflammatory stress small resistance arteries" primary arterial hypertension, angiotensin-converting enzyme 2, COVID-19, SARS-CoV2, endothelial dysfunction, renin–angiotensin–aldosterone system, oxidative and inflammatory stress, small resistance arteries" dvips + MiKTeX GPL Ghostscript 9.0 uuid:18894b8b-a6fc-4d13-a704-fbc8c243b7c4 uuid:8f044db2-120b-47ce-9c38-13d86a7c7df8 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 229, 755 Annotation: Subtype: Link Rect: 504, 736, 551, 744 Annotation: Subtype: Link Rect: 464, 728, 507, 736 Annotation: Subtype: Link Rect: 507, 729, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 451, 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