34e86d2270ee938581dad609a7bae06e PATH_a2020v9n374.pdf 02406c4602d29eaf70ccaf99be559a026f619783 PATH_a2020v9n374.pdf 9d89662dfa108f63153e436a748d5b5a1618ce74b342b774ad46ee3246ffa4fb PATH_a2020v9n374.pdf Title: Update on Streptococcus suis Research and Prevention in the Era of Antimicrobial Restriction: 4th International Workshop on S. suis "2279 Subject: Streptococcus suis is a swine pathogen and a zoonotic agent afflicting people in close contact with infected pigs or pork meat. Sporadic cases of human infections have been reported worldwide. In addition, S. suis outbreaks emerged in Asia, making this bacterium a primary health concern in this part of the globe. In pigs, S. suis disease results in decreased performance and increased mortality, which have a significant economic impact on swine production worldwide. Facing the new regulations in preventive use of antimicrobials in livestock and lack of effective vaccines, control of S. suis infections is worrisome. Increasing and sharing of knowledge on this pathogen is of utmost importance. As such, the pathogenesis and epidemiology of the infection, antimicrobial resistance, progress on diagnosis, prevention, and control were among the topics discussed during the 4th International Workshop on Streptococcus suis (held in Montreal, Canada, June 2019). This review gathers together recent findings on this important pathogen from lectures performed by lead researchers from several countries including Australia, Canada, France, Germany, Japan, Spain, Thailand, The Netherlands, UK, and USA. Finally, policies and recommendations for the manufacture, quality control, and use of inactivated autogenous vaccines are addressed to advance this important field in veterinary medicine. Keywords: Streptococcus suis; swine; zoonosis; epidemiology; genomics; diagnosis; antimicrobials; vaccines; public health; vaccine policies Author: Mariela Segura, Virginia Aragon, Susan L. Brockmeier, Connie Gebhart, Astrid de Greeff, Anusak Kerdsin, Mark A O’Dea, Masatoshi Okura, Mariette Saléry, Constance Schultsz, Peter Valentin-Weigand, Lucy A. Weinert, Jerry M. 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