90dc3e81c7adacb2b96ebefb795a85e7 283348.pdf bb42c393d4599993823829db65254a1c45774157 283348.pdf e1bc5f0870aee56d6ad8954667074441ebddd402f78eb1cc47e81b38b3dad463 283348.pdf Title: Airway Hyperresponsiveness, Inflammation, and Pulmonary Emphysema in Rodent Models Designed to Mimic Exposure to Fuel Oil–Derived Volatile Organic Compounds Encountered during an Experimental Oil Spill Subject: Environ Health Perspect 2020.128:027003 Author: &hx00D3 Creator: PTC Arbortext Advanced Print Publisher 11.1.4012/W Producer: Adobe LiveCycle PDFG ES; modified using iText 4.2.0 by 1T3XT CreationDate: Wed Feb 12 09:55:49 2020 CET ModDate: Wed Oct 11 10:01:38 2023 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 612 x 792 pts (letter) Page rot: 0 File size: 3606044 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LICLIC+AdvOTe3b1fbf3.B Type 1C WinAnsi yes yes no 32 0 LICLIE+AdvOT864ae8b9.BI Type 1C WinAnsi yes yes no 33 0 LICLID+AdvOTe3b1fbf3.B+20 Type 1C WinAnsi yes yes no 564 0 LICLKM+AdvOTce3d9a73 Type 1C WinAnsi yes yes no 565 0 LICLKJ+AdvOT10f0fcb1 Type 1C WinAnsi yes yes no 31 0 LICLKL+AdvOT46dcae81+20 Type 1C WinAnsi yes yes no 566 0 LICLJI+AdvOTeea082cb Type 1C WinAnsi yes yes no 30 0 LICLKK+AdvOT46dcae81 Type 1C WinAnsi yes yes no 567 0 LICLIG+AdvOTb0c9bf5d+20 Type 1C WinAnsi yes yes no 36 0 LICLIF+AdvOTb0c9bf5d Type 1C WinAnsi yes yes no 35 0 LICLJH+AdvOTb0c9bf5d+fb Type 1C Custom yes yes yes 29 0 LICLJG+AdvOT6bc95374.I Type 1C WinAnsi yes yes no 37 0 LICLLO+AdvP4C4E51 Type 1C WinAnsi yes yes no 34 0 LICLLN+AdvP4C4E59 Type 1C Custom yes yes no 38 0 LICLOB+AdvP4C4E74 Type 1C Custom yes yes no 60 0 LICLOC+AdvOTb0c9bf5d+21 Type 1C WinAnsi yes yes no 57 0 LICLNP+AdvPSMP13 Type 1C WinAnsi yes yes no 61 0 LICLOA+AdvOTb0c9bf5d+22 Type 1C Custom yes yes no 53 0 LICLNO+AdvTT716680a6 Type 1C WinAnsi yes yes no 62 0 LIDPCF+AdvOTb4959fff+20 Type 1C WinAnsi yes yes no 227 0 LIDPCE+AdvOTb4959fff Type 1C WinAnsi yes yes no 228 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-10-12 02:23:20 CEST RepresentationInformation: 283348.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-10-11 10:56:05 CEST Size: 3606044 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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referenced object 'bkmk_c34' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_f10' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c13' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c14' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c52' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c69' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c69' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c70' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c40' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c58' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c22' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c65' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c52' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c20' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c31' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c42' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c52' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c52' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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referenced object 'bkmk_c59' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c39' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c67' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c33' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c28' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bkmk_c10' cannot be found Offset: 3604442 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Children: Item: Title: Animals Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Study Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Fuel Oil Source and Specifications Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Exposure System Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Fuel Oil Volatile Organic Compound Composition Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: Airway Hyperresponsiveness to Methacholine Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Bronchoalveolar Lavage Collection and Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: Lung Tissue Processing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Quantification of Pulmonary Emphysema Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Detection and Quantification of Apoptotic Structural Alveolar Septal Cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Item: Title: Immunohistochemical Detection and Quantification of CD31, Vascular Endothelial Growth Factor, CD8, and Neutrophil Elastase Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3 Item: Title: Data Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@32eebfca Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207 Children: Item: Title: Evaluation of Airway Responsiveness to Methacholine Challenge Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d Item: Title: Bronchoalveolar Lavage Analyses and Airway Histopathology Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@543c6f6d Item: Title: Detection and Quantitative Analysis of Pulmonary Emphysema Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13eb8acf Item: Title: Detection and Quantification of Structural Alveolar Septal Cell Apoptosis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@51c8530f Item: Title: Frequency of CD8+ T Cells in the Lung Parenchyma Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7403c468 Item: Title: Analysis of Parenchymal Microvascular Response Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43738a82 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@c81cdd1 Item: Title: Acknowledgments Destination: 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