82edb82e54ddd3f879ab84265ae560da 283369.pdf 552e2babc6966d2c92bf4967ab9cda9ec3a6aedf 283369.pdf ae30e8cffcce285250456b3ec444dda3a4ab1c6d564b3c4b5ed2f6bd9f3ee0b2 283369.pdf Producer: iText® 7.1.1 ©2000-2018 iText Group NV (AGPL-version) CreationDate: Wed Jan 22 04:02:32 2020 CET ModDate: Wed Jan 22 04:02:32 2020 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2195622 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- BTFGED+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 DRXAWD+VnURWPalladioL Type 1 Custom yes yes no 15 0 FZXJFF+URWPalladioL-Ital Type 1 Custom yes yes no 19 0 DRMUDV+URWPalladioL-Bold Type 1 Custom yes yes no 24 0 FKWMCN+URWPalladioL-Roma Type 1 Custom yes yes no 28 0 HAKARX+Rpxr Type 1 Builtin yes yes no 32 0 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PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 474 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Material and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Children: Item: Title: HL-1 Cardiomyocyte-Derived Cell Line, Cultures, and Reagents Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: LDL Isolation and Modification Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: DiI-Labeling of LDL Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Lipid Extraction and Determination of CE, TG, and FC Content Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Western Blot Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: Confocal Microscopy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Item: Title: Real Time-PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@a38d7a3 Item: Title: Immunoprecipitation (IP) Assays Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77f99a05 Item: Title: Biotin-Labeling Cell Surface Protein Assay Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@63440df3 Item: Title: 2-NBDG Uptake Assay Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3aeaafa6 Item: Title: Statistical Treatment of Data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@76a3e297 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Children: Item: Title: LRP1 Mediates Intracellular CE Accumulation by AggLDL Endocytosis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: Aggregated LDL Endocytosis Leads to AggLDL/LRP1 Complex Accumulation in Endosomal Compartments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Aggregated LDL Reduces the Molecular Association Between LRP1 and IR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Aggregated LDL Impairs Insulin-Induced Intracellular Signaling Activation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Aggregated LDL Affects the GLUT4 Traffic to the Cell Surface and Glucose Uptake Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: References Destination: 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