7e9e890612ff94c4f94e6eb5905b6c01  283894.pdf
98662cc6016355089975fa994d7a692782209bf8  283894.pdf
bcc778aacfafbd74bf1c2561664947a38f149839aafb2817acb6a1922b85a78b  283894.pdf

Title:          Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
Subject:        Translational Psychiatry, doi:10.1038/s41398-020-01074-z
Keywords:       
Author:         Shengjun Hong
Creator:        Springer
Producer:       iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
CreationDate:   Sun Nov 22 05:33:48 2020 CET
ModDate:        Sun Nov 22 08:27:57 2020 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           AcroForm
JavaScript:     no
Pages:          12
Encrypted:      no
Page size:      595.276 x 790.866 pts
Page rot:       0
File size:      1351912 bytes
Optimized:      no
PDF version:    1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
KBLKNB+AdvOT07517017+03              Type 1C           Custom           yes yes yes    189  0
KBLJFH+AdvOT07517017                 Type 1C           WinAnsi          yes yes no      69  0
KBLKNC+AdvOT0d9ab1db.I               Type 1C           WinAnsi          yes yes no     171  0
KBLJLF+AdvOT07517017+20              Type 1C           WinAnsi          yes yes no     172  0
KBLKNA+AdvOT07517017+fb              Type 1C           Custom           yes yes yes     70  0
KBLLAG+AdvAGaramond-R                Type 1C           WinAnsi          yes yes no      58  0
KBLKOE+AdvOTa9103878+03              Type 1C           Custom           yes yes yes     60  0
KBLKPF+AdvOTce3d9a73                 Type 1C           WinAnsi          yes yes no      61  0
KBLKOC+AdvOTa9103878                 Type 1C           WinAnsi          yes yes no      62  0
KBLKOD+AdvOTa9103878+20              Type 1C           WinAnsi          yes yes no      64  0
KBLJCC+AdvOT46dcae81                 Type 1C           WinAnsi          yes yes no     228  0
KBLJCD+AdvOT65f8a23b.I               Type 1C           WinAnsi          yes yes no     229  0
KBLJCE+AdvMyriad_R                   Type 1C           WinAnsi          yes yes no     514  0
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  no     515  0
KBLJEF+AdvOT3b30f6db.B               Type 1C           WinAnsi          yes yes no      63  0
KBLJEG+AdvOT46dcae81+20              Type 1C           WinAnsi          yes yes no     516  0
KBLLBH+AdvOTa9103878+fb              Type 1C           Custom           yes yes yes     56  0
KBLLBI+AdvTTab7e17fd                 Type 1C           WinAnsi          yes yes no      57  0
KBLLBG+AdvOTf0bf83d5.I               Type 1C           WinAnsi          yes yes no      59  0
KBLLDJ+AdvOTa9103878+22              Type 1C           Custom           yes yes yes    107  0
KBLLDK+AdvOTce3d9a73+fb              Type 1C           Custom           yes yes yes    108  0
KBLLCJ+AdvTT67e40053                 Type 1C           WinAnsi          yes yes no     109  0
KBLLDL+AdvOT56309c18.I               Type 1C           WinAnsi          yes yes no     110  0
KBLLFN+AdvOTce3d9a73+20              Type 1C           WinAnsi          yes yes no     151  0
KBLLEM+AdvOTf0bf83d5.I+03            Type 1C           Custom           yes yes yes    152  0
KBMKPP+AdvOT0d9ab1db.I+03            Type 1C           Custom           yes yes yes    173  0
KBLLFO+AdvTTab7e17fd+22              Type 1C           Custom           yes yes no     174  0
KBNIAA+AdvOTce3d9a73+03              Type 1C           Custom           yes yes yes    190  0
KBNICB+AdvOT46dcae81+fb              Type 1C           Custom           yes yes yes    226  0
KBNIBA+AdvOTd0125be5.BI              Type 1C           WinAnsi          yes yes no     227  0
KBNIGB+AdvOT0d9ab1db.I+20            Type 1C           WinAnsi          yes yes no     265  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2023-10-28 02:23:26 CEST
 RepresentationInformation: 283894.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2023-10-27 09:45:48 CEST
  Size: 1351912
  Format: PDF
  Version: 1.4
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR12' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR14' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR15' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR26' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR27' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR28' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR29' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR30' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 796354
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 637
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: EN
    Outlines: 
     Item: 
      Title: Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71
      Children: 
       Item: 
        Title: Introduction
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2
       Item: 
        Title: Materials and methods
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9
        Children: 
         Item: 
          Title: Sample and phenotype description
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f
         Item: 
          Title: DNA extraction
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78
         Item: 
          Title: Genotype imputation and quality control
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee
         Item: 
          Title: Classification of APOE genotypes
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f
         Item: 
          Title: Biochemical analyses of CSF biomarkers
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1
         Item: 
          Title: GWAS and post-GWAS analyses
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d
         Item: 
          Title: Polygenic risk score (PRS) analysis
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89
         Item: 
          Title: Validation analyses in ADNI
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e
        Children: 
         Item: 
          Title: GWAS on diagnostic outcomes
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b
         Item: 
          Title: GWAS on dichotomous “amyloid classification”
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b
         Item: 
          Title: GWAS on additional dichotomous and continuous CSF amyloid variables
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31
         Item: 
          Title: GWAS on dichotomous and continuous CSF tau variables
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107
         Item: 
          Title: Polygenic risk score (PRS) analyses on all outcome traits
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e
       Item: 
        Title: Discussion
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7
       Item: 
        Title: Acknowledgements
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e
       Item: 
        Title: Acknowledgements
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247
   Info: 
    Title: Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
    Author: Shengjun Hong
    Subject: Translational Psychiatry, doi:10.1038/s41398-020-01074-z
    Keywords: 
    Creator: Springer
    Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
    CreationDate: Sun Nov 22 06:03:48 CET 2020
    ModDate: Sun Nov 22 08:27:57 CET 2020
   ID: 0xa93aac6e44d9fb272d0f1cc6c36cc441, 0xb83db6293ac131df47964ba3a78251f2
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1950
      ImageHeight: 1674
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1950
      ImageHeight: 1658
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1100
      ImageHeight: 90
      ColorSpace: black is zero
      BitsPerSample: 1
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: KBLKOD+AdvOTa9103878+20
      FontSubset: true
      FirstChar: 146
      LastChar: 151
      FontDescriptor: 
       FontName: KBLKOD+AdvOTa9103878+20
       Flags: Nonsymbolic
       FontBBox: -166, -218, 968, 812
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLJCE+AdvMyriad_R
      FontSubset: true
      FirstChar: 35
      LastChar: 95
      FontDescriptor: 
       FontName: KBLJCE+AdvMyriad_R
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MyriadPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLJEG+AdvOT46dcae81+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: KBLJEG+AdvOT46dcae81+20
       Flags: Nonsymbolic
       FontBBox: 0, -197, 1125, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLJFH+AdvOT07517017
      FontSubset: true
      FirstChar: 35
      LastChar: 252
      FontDescriptor: 
       FontName: KBLJFH+AdvOT07517017
       Flags: Nonsymbolic
       FontBBox: -41, -250, 812, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLKNA+AdvOT07517017+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: KBLKNA+AdvOT07517017+fb
       Flags: Symbolic
       FontBBox: 0, 0, 677, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBNIGB+AdvOT0d9ab1db.I+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: KBNIGB+AdvOT0d9ab1db.I+20
       Flags: Nonsymbolic
       FontBBox: -62, -197, 1000, 822
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLFN+AdvOTce3d9a73+20
      FontSubset: true
      FirstChar: 146
      LastChar: 148
      FontDescriptor: 
       FontName: KBLLFN+AdvOTce3d9a73+20
       Flags: Nonsymbolic
       FontBBox: -156, -197, 1197, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLEM+AdvOTf0bf83d5.I+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: KBLLEM+AdvOTf0bf83d5.I+03
       Flags: Symbolic
       FontBBox: -114, -239, 937, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBNICB+AdvOT46dcae81+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: KBNICB+AdvOT46dcae81+fb
       Flags: Symbolic
       FontBBox: 0, 0, 739, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBNIBA+AdvOTd0125be5.BI
      FontSubset: true
      FirstChar: 65
      LastChar: 80
      FontDescriptor: 
       FontName: KBNIBA+AdvOTd0125be5.BI
       Flags: Nonsymbolic
       FontBBox: -93, -250, 927, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLJCC+AdvOT46dcae81
      FontSubset: true
      FirstChar: 40
      LastChar: 122
      FontDescriptor: 
       FontName: KBLJCC+AdvOT46dcae81
       Flags: Nonsymbolic
       FontBBox: -41, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLJCD+AdvOT65f8a23b.I
      FontSubset: true
      FirstChar: 80
      LastChar: 121
      FontDescriptor: 
       FontName: KBLJCD+AdvOT65f8a23b.I
       Flags: Nonsymbolic
       FontBBox: -104, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLKNC+AdvOT0d9ab1db.I
      FontSubset: true
      FirstChar: 37
      LastChar: 122
      FontDescriptor: 
       FontName: KBLKNC+AdvOT0d9ab1db.I
       Flags: Nonsymbolic
       FontBBox: -114, -250, 864, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLDJ+AdvOTa9103878+22
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: KBLLDJ+AdvOTa9103878+22
       Flags: Symbolic
       FontBBox: -166, -166, 718, 864
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLJLF+AdvOT07517017+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: KBLJLF+AdvOT07517017+20
       Flags: Nonsymbolic
       FontBBox: 0, -208, 1041, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLDK+AdvOTce3d9a73+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: KBLLDK+AdvOTce3d9a73+fb
       Flags: Symbolic
       FontBBox: 0, 0, 791, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLLCJ+AdvTT67e40053
      FontSubset: true
      FirstChar: 174
      LastChar: 174
      FontDescriptor: 
       FontName: KBLLCJ+AdvTT67e40053
       Flags: Nonsymbolic
       FontBBox: -72, -218, 927, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBMKPP+AdvOT0d9ab1db.I+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: KBMKPP+AdvOT0d9ab1db.I+03
       Flags: Symbolic
       FontBBox: -62, -197, 729, 781
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLLDL+AdvOT56309c18.I
      FontSubset: true
      FirstChar: 65
      LastChar: 114
      FontDescriptor: 
       FontName: KBLLDL+AdvOT56309c18.I
       Flags: Nonsymbolic
       FontBBox: -93, -250, 906, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLFO+AdvTTab7e17fd+22
      FontSubset: true
      FirstChar: 21
      LastChar: 21
      FontDescriptor: 
       FontName: KBLLFO+AdvTTab7e17fd+22
       Flags: Nonsymbolic
       FontBBox: -156, -218, 937, 947
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: KBLLBH+AdvOTa9103878+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: KBLLBH+AdvOTa9103878+fb
       Flags: Symbolic
       FontBBox: 0, -10, 812, 708
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLLBI+AdvTTab7e17fd
      FontSubset: true
      FirstChar: 43
      LastChar: 61
      FontDescriptor: 
       FontName: KBLLBI+AdvTTab7e17fd
       Flags: Nonsymbolic
       FontBBox: -156, -250, 1072, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLAG+AdvAGaramond-R
      FontSubset: true
      FirstChar: 35
      LastChar: 95
      FontDescriptor: 
       FontName: KBLLAG+AdvAGaramond-R
       Flags: Nonsymbolic
       FontBBox: -177, -260, 1093, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLLBG+AdvOTf0bf83d5.I
      FontSubset: true
      FirstChar: 49
      LastChar: 121
      FontDescriptor: 
       FontName: KBLLBG+AdvOTf0bf83d5.I
       Flags: Serif, Nonsymbolic
       FontBBox: -187, -239, 1062, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLKOE+AdvOTa9103878+03
      FontSubset: true
      FirstChar: 1
      LastChar: 4
      FontDescriptor: 
       FontName: KBLKOE+AdvOTa9103878+03
       Flags: Symbolic
       FontBBox: -135, -250, 906, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLKNB+AdvOT07517017+03
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: KBLKNB+AdvOT07517017+03
       Flags: Symbolic
       FontBBox: -20, -197, 708, 781
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLKPF+AdvOTce3d9a73
      FontSubset: true
      FirstChar: 35
      LastChar: 121
      FontDescriptor: 
       FontName: KBLKPF+AdvOTce3d9a73
       Flags: Nonsymbolic
       FontBBox: -41, -250, 854, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBLKOC+AdvOTa9103878
      FontSubset: true
      FirstChar: 37
      LastChar: 252
      FontDescriptor: 
       FontName: KBLKOC+AdvOTa9103878
       Flags: Serif, Nonsymbolic
       FontBBox: -20, -239, 1020, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: KBNIAA+AdvOTce3d9a73+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: KBNIAA+AdvOTce3d9a73+03
       Flags: Symbolic
       FontBBox: -52, -218, 770, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KBLJEF+AdvOT3b30f6db.B
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: KBLJEF+AdvOT3b30f6db.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta x:xmptk="Adobe XMP Core 5.2-c001 63.143651, 2012/04/05-09:01:49        " xmlns:x="adobe:ns:meta/">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about="" xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1038/s41398-020-01074-z</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Shengjun Hong</rdf:li>
               <rdf:li>Dmitry Prokopenko</rdf:li>
               <rdf:li>Valerija Dobricic</rdf:li>
               <rdf:li>Fabian Kilpert</rdf:li>
               <rdf:li>Isabelle Bos</rdf:li>
               <rdf:li>Stephanie J. B. Vos</rdf:li>
               <rdf:li>Betty M. Tijms</rdf:li>
               <rdf:li>Ulf Andreasson</rdf:li>
               <rdf:li>Kaj Blennow</rdf:li>
               <rdf:li>Rik Vandenberghe</rdf:li>
               <rdf:li>Isabelle Cleynen</rdf:li>
               <rdf:li>Silvy Gabel</rdf:li>
               <rdf:li>Jolien Schaeverbeke</rdf:li>
               <rdf:li>Philip Scheltens</rdf:li>
               <rdf:li>Charlotte E. Teunissen</rdf:li>
               <rdf:li>Ellis Niemantsverdriet</rdf:li>
               <rdf:li>Sebastiaan Engelborghs</rdf:li>
               <rdf:li>Giovanni Frisoni</rdf:li>
               <rdf:li>Olivier Blin</rdf:li>
               <rdf:li>Jill C. Richardson</rdf:li>
               <rdf:li>Regis Bordet</rdf:li>
               <rdf:li>José Luis Molinuevo</rdf:li>
               <rdf:li>Lorena Rami</rdf:li>
               <rdf:li>Petronella Kettunen</rdf:li>
               <rdf:li>Anders Wallin</rdf:li>
               <rdf:li>Alberto Lleó</rdf:li>
               <rdf:li>Isabel Sala</rdf:li>
               <rdf:li>Julius Popp</rdf:li>
               <rdf:li>Gwendoline Peyratout</rdf:li>
               <rdf:li>Pablo Martinez-Lage</rdf:li>
               <rdf:li>Mikel Tainta</rdf:li>
               <rdf:li>Richard J. B. Dobson</rdf:li>
               <rdf:li>Cristina Legido-Quigley</rdf:li>
               <rdf:li>Kristel Sleegers</rdf:li>
               <rdf:li>Christine Broeckhoven</rdf:li>
               <rdf:li>Mara Kate</rdf:li>
               <rdf:li>Frederik Barkhof</rdf:li>
               <rdf:li>Henrik Zetterberg</rdf:li>
               <rdf:li>Simon Lovestone</rdf:li>
               <rdf:li>Johannes Streffer</rdf:li>
               <rdf:li>Michael Wittig</rdf:li>
               <rdf:li>Andre Franke</rdf:li>
               <rdf:li>Rudolph E. Tanzi</rdf:li>
               <rdf:li>Pieter Jelle Visser</rdf:li>
               <rdf:li>Lars Bertram</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Springer US</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:subject>
            <rdf:Bag></rdf:Bag>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Translational Psychiatry, doi:10.1038/s41398-020-01074-z</rdf:li>
            </rdf:Alt>
         </dc:description>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/">
         <prism:doi>10.1038/s41398-020-01074-z</prism:doi>
         <prism:url>http://dx.doi.org/10.1038/s41398-020-01074-z</prism:url>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Translational Psychiatry</prism:publicationName>
         <prism:copyright>© 2020, The Author(s)</prism:copyright>
         <prism:issn>2158-3188</prism:issn>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:doi>10.1038/s41398-020-01074-z</pdfx:doi>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>True</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1038/s41398-020-01074-z</crossmark:DOI>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2020-11-22T08:27:57+01:00</xmp:ModifyDate>
         <xmp:CreateDate>2020-11-22T10:03:48+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2020-11-22T08:27:57+01:00</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords></pdf:Keywords>
      <pdf:Producer>iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)</pdf:Producer></rdf:Description>
      <rdf:Description rdf:about="" xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#" xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:491f047b-8cf3-4d13-bbe5-68ede20a2049</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:998f37b3-91d0-4095-9f04-105614f98762</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:5dcf9826-eeac-4bf3-b947-94e1e14c53cc</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2020-11-22T10:04:34+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/">
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:author="http://springernature.com/ns/xmpExtensions/2.0/authorInfo/" xmlns:sn="http://springernature.com/ns/xmpExtensions/2.0/">
         <sn:authorInfo>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Betty M. Tijms</author:name>
                  <author:orcid>http://orcid.org/0000-0002-2612-1797</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Kaj Blennow</author:name>
                  <author:orcid>http://orcid.org/0000-0002-1890-4193</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Philip Scheltens</author:name>
                  <author:orcid>http://orcid.org/0000-0002-1046-6408</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Sebastiaan Engelborghs</author:name>
                  <author:orcid>http://orcid.org/0000-0003-0304-9785</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Petronella Kettunen</author:name>
                  <author:orcid>http://orcid.org/0000-0002-2510-3423</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Anders Wallin</author:name>
                  <author:orcid>http://orcid.org/0000-0001-9506-0513</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Richard J. B. Dobson</author:name>
                  <author:orcid>http://orcid.org/0000-0003-4224-9245</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Kristel Sleegers</author:name>
                  <author:orcid>http://orcid.org/0000-0002-0283-2332</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Henrik Zetterberg</author:name>
                  <author:orcid>http://orcid.org/0000-0003-3930-4354</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Andre Franke</author:name>
                  <author:orcid>http://orcid.org/0000-0003-1530-5811</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Rudolph E. Tanzi</author:name>
                  <author:orcid>http://orcid.org/0000-0002-7032-1454</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Pieter Jelle Visser</author:name>
                  <author:orcid>http://orcid.org/0000-0001-8008-9727</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Lars Bertram</author:name>
                  <author:orcid>http://orcid.org/0000-0002-0108-124X</author:orcid>
               </rdf:li>
            </rdf:Bag>
         </sn:authorInfo>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/" xmlns:pdfaField="http://www.aiim.org/pdfa/ns/field#" xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#" xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#" xmlns:pdfaType="http://www.aiim.org/pdfa/ns/type#">
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>pdfx</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrosMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:DOI</pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://crossref.org/crossmark/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>crossmark</pdfaSchema:prefix>
                  <pdfaSchema:schema>crossmark</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Usual same as prism:doi</pdfaProperty:description>
                           <pdfaProperty:name>DOI</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The date when a publication was published.</pdfaProperty:description>
                           <pdfaProperty:name>MajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://prismstandard.org/namespaces/basic/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>prism</pdfaSchema:prefix>
                  <pdfaSchema:schema>Prism</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. 
Comment 
PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. 
Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. 

</pdfaProperty:description>
                           <pdfaProperty:name>aggregationType</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Copyright </pdfaProperty:description>
                           <pdfaProperty:name>copyright</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article.
The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. 
If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). 
</pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. 
Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. 
</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. 
Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. 

Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” 
</pdfaProperty:description>
                           <pdfaProperty:name>publicationName</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. 
The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. 
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. 
</pdfaProperty:description>
                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>sn</pdfaSchema:prefix>
                  <pdfaSchema:schema>Springer Nature ORCID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.</pdfaProperty:description>
                           <pdfaProperty:name>authorInfo</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag AuthorInformation</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:description>Specifies the types of author information: name and ORCID of an author.</pdfaType:description>
                           <pdfaType:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/authorInfo/</pdfaType:namespaceURI>
                           <pdfaType:prefix>author</pdfaType:prefix>
                           <pdfaType:type>AuthorInformation</pdfaType:type>
                           <pdfaType:field>
                              <rdf:Seq>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:description>Gives the name of an author.</pdfaField:description>
                                    <pdfaField:name>name</pdfaField:name>
                                    <pdfaField:valueType>Text</pdfaField:valueType>
                                 </rdf:li>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:description>Gives the ORCID of an author.</pdfaField:description>
                                    <pdfaField:name>orcid</pdfaField:name>
                                    <pdfaField:valueType>URI</pdfaField:valueType>
                                 </rdf:li>
                              </rdf:Seq>
                           </pdfaType:field>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.niso.org/schemas/jav/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
                           <pdfaProperty:name>journal_article_version</pdfaProperty:name>
                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 522, 579, 523, 589
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 522, 579, 523, 589
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 532, 579, 533, 589
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 523, 579, 532, 589
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 530, 579, 532, 589
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 173, 566, 174, 576
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 173, 566, 174, 576
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 183, 566, 184, 576
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 174, 566, 183, 576
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 181, 566, 183, 576
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 115, 553, 116, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 115, 553, 116, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 125, 553, 126, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 116, 553, 125, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 123, 553, 125, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 408, 553, 409, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 408, 553, 409, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 417, 553, 418, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 409, 553, 417, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 416, 553, 417, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 191, 527, 192, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 191, 527, 192, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 201, 527, 202, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 192, 527, 201, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 199, 527, 201, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 266, 527, 266, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 266, 527, 266, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 275, 527, 276, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 267, 527, 275, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 274, 527, 275, 537
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 279, 514, 280, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 279, 514, 280, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 289, 514, 290, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 280, 514, 289, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 287, 514, 289, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 491, 514, 492, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 491, 514, 492, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 501, 514, 502, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 492, 514, 501, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 499, 514, 501, 524
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 388, 501, 389, 511
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 388, 501, 389, 511
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 398, 501, 399, 511
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 389, 501, 398, 511
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 396, 501, 398, 511
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 256, 488, 257, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 256, 488, 257, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 266, 488, 267, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 257, 488, 266, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 264, 488, 266, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 339, 488, 340, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 339, 488, 340, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 349, 488, 350, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 340, 488, 349, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 347, 488, 349, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 419, 488, 420, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 419, 488, 420, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 429, 488, 430, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 420, 488, 429, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 427, 488, 429, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 498, 488, 499, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 498, 488, 499, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 508, 488, 509, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 500, 488, 508, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 507, 488, 508, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 269, 59, 385, 66
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 151, 227, 235, 235
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 137, 155, 186, 163
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 227, 128, 283, 136
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 120, 281, 127
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 77, 696, 81, 706
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 82, 696, 86, 706
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 225, 648, 228, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 128, 612, 132, 622
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 183, 577, 186, 586
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 75, 529, 78, 539
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 80, 529, 84, 539
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 171, 505, 175, 515
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 179, 505, 183, 515
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 155, 457, 159, 467
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 160, 457, 164, 467
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 138, 397, 142, 407
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 89, 373, 93, 383
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 95, 373, 102, 383
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 113, 182, 120, 192
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 195, 122, 202, 132
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 181, 62, 189, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 378, 369, 383, 379
       Flags: Print
       AppearanceDictionary: true
       Destination: 65
      Annotation: 
       Subtype: Link
       Rect: 531, 266, 538, 275
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 332, 178, 337, 187
       Flags: Print
       AppearanceDictionary: true
       Destination: 65
      Annotation: 
       Subtype: Link
       Rect: 326, 134, 333, 144
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 485, 106, 538, 116
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 304, 94, 319, 104
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 3
     Thumb: true
    Page: 
     Label: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 77, 553, 84, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 234, 230, 242, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 230, 218, 237, 228
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 261, 170, 268, 180
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 200, 158, 207, 168
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 385, 457, 392, 467
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 468, 326, 475, 335
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 441, 278, 449, 287
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 472, 230, 479, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 481, 230, 488, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 504, 218, 511, 228
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 513, 218, 520, 228
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 478, 94, 538, 104
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 304, 82, 348, 92
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 470, 86, 477, 96
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 336, 62, 344, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 243, 672, 250, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 252, 672, 259, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 177, 656, 264, 666
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 267, 660, 275, 670
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 283, 624, 290, 634
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 140, 565, 147, 574
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 286, 505, 290, 515
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 284, 469, 288, 479
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 220, 409, 228, 419
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 116, 106, 268, 116
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 516, 397, 519, 407
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 364, 385, 368, 395
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 387, 326, 395, 335
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 439, 130, 444, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 65
      Annotation: 
       Subtype: Link
       Rect: 455, 62, 462, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 219, 178, 224, 187
       Flags: Print
       AppearanceDictionary: true
       Destination: 157
      Annotation: 
       Subtype: Link
       Rect: 74, 130, 78, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 157
      Annotation: 
       Subtype: Link
       Rect: 404, 214, 409, 223
       Flags: Print
       AppearanceDictionary: true
       Destination: 157
      Annotation: 
       Subtype: Link
       Rect: 464, 158, 468, 168
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 532, 146, 536, 156
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
     Thumb: true
    Page: 
     Label: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 238, 58, 243, 68
       Flags: Print
       AppearanceDictionary: true
       Destination: 65
      Annotation: 
       Subtype: Link
       Rect: 531, 118, 536, 128
       Flags: Print
       AppearanceDictionary: true
       Destination: 179
      Annotation: 
       Subtype: Link
       Rect: 390, 74, 398, 84
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 280, 608, 285, 618
       Flags: Print
       AppearanceDictionary: true
       Destination: 179
      Annotation: 
       Subtype: Link
       Rect: 86, 417, 91, 427
       Flags: Print
       AppearanceDictionary: true
       Destination: 65
      Annotation: 
       Subtype: Link
       Rect: 140, 254, 147, 264
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 126, 194, 134, 204
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 181, 62, 188, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 417, 493, 420, 503
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 493, 493, 497, 503
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 462, 321, 467, 331
       Flags: Print
       AppearanceDictionary: true
       Destination: 220
      Annotation: 
       Subtype: Link
       Rect: 354, 302, 358, 311
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
      Annotation: 
       Subtype: Link
       Rect: 479, 302, 483, 311
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
     Thumb: true
    Page: 
     Label: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 89, 339, 97, 342
       Flags: Print
       AppearanceDictionary: true
       Destination: 251
     Thumb: true
    Page: 
     Label: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 122, 632, 127, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 220
      Annotation: 
       Subtype: Link
       Rect: 522, 684, 530, 694
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 444, 230, 451, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 11
     Thumb: true
    Page: 
     Label: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 233, 469, 279, 477
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 460, 140, 468
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 320, 576, 417, 583
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 469, 450, 538, 458
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 320, 441, 348, 449
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: 822c9b0a
   Type: CRC32
  Checksum: 7e9e890612ff94c4f94e6eb5905b6c01
   Type: MD5
  Checksum: 98662cc6016355089975fa994d7a692782209bf8
   Type: SHA-1