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EIGPPH+Arial-BoldMT FontSubset: true FirstChar: 65 LastChar: 69 FontDescriptor: FontName: EIGPPH+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIHAAI+Arial-ItalicMT FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: EIHAAI+Arial-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.jtho.2019.10.013 Randomized Phase II Study of Paclitaxel plus Alisertib versus Paclitaxel plus Placebo as Second-Line Therapy for SCLC: Primary and Correlative Biomarker Analyses Taofeek K. Owonikoko MD Huifeng Niu PhD Kristiaan Nackaerts MD PhD Tibor Csoszi MD Gyula Ostoros MD Zsuzsanna Mark MD Christina Baik MD MPH Anil Abraham Joy MD Christos Chouaid MD Jesus Corral Jaime MD Vitezslav Kolek MD PhD Margarita Majem MD PhD Jaromir Roubec MD PhD Edgardo S. Santos MD FACP Anne C. Chiang MD PhD Giovanna Speranza MD Chandra P. Belani MD Alberto Chiappori MD Manish R. Patel MD Krisztina Czebe MD Lauren Byers MD Brittany Bahamon BSc Cong Li PhD Emily Sheldon-Waniga PhD Eric F. Kong PhD Miguel Williams MS Sunita Badola MSc Hyunjin Shin PhD Lisa Bedford MSc Jeffrey A. Ecsedy PhD Matthew Bryant BSc Sian Jones PhD John Simmons PhD E. Jane Leonard MSc Claudio Dansky Ullmann MD PhD David R. Spigel MD C14018 study investigators Phase II Aurora A kinase Alisertib Paclitaxel SCLC Journal of Thoracic Oncology, 15 (2020) 274-287. doi:10.1016/j.jtho.2019.10.013 Elsevier Inc journal Journal of Thoracic Oncology © 2019 International Association for the Study of Lung Cancer. Published by Elsevier Inc. 1556-0864 15 2 February 2020 274-287 274 287 10.1016/j.jtho.2019.10.013 https://doi.org/10.1016/j.jtho.2019.10.013 2010-04-23 true 10.1016/j.jtho.2019.10.013 elsevier.com sciencedirect.com VoR 6.5 10.1016/j.jtho.2019.10.013 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2020-01-22T23:30:08+05:30 2020-01-23T18:37:23+05:30 2020-01-23T18:37:23+05:30 True Acrobat Distiller 8.1.0 (Windows) uuid:01d874b8-56c4-4bf1-bdc6-12241637e0ae uuid:4e220684-ee6f-472c-921c-205a648fa58d http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 274 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 192, 580, 197, 592 Destination: 1 Annotation: Subtype: Link Rect: 302, 580, 307, 592 Destination: 1 Annotation: Subtype: Link Rect: 471, 580, 475, 592 Destination: 1 Annotation: Subtype: Link Rect: 137, 567, 142, 579 Destination: 1 Annotation: Subtype: Link Rect: 248, 567, 253, 579 Destination: 1 Annotation: Subtype: Link Rect: 368, 567, 371, 579 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