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INTRODUCTION Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 2. MATERIALS AND METHODS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: 2.1. Study design and participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 2.2. Ethics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 2.3. General laboratory measurements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: 2.4. Genetic studies Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: 2.5. Plasma chemokine concentrations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: 2.6. Statistical analyses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: 2.7. Role of funders Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: 3. RESULTS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Children: Item: Title: 3.1. Patient characteristics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: 3.2. SDF-1 and MCP-1 are prognostic markers of the immune response to cART Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: 3.3. SDF-1 is a marker of poor progression, and the MCP-1and MIP-α are markers of DeltaCD4+ T-cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: 3.4. Genetic association study of chemokine (CXCL12 and CCL5) gene variants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: 3.5. Genetic association study of selected chemokine receptor gene variants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: 3.6. CXCL12 rs1801157 and CCL5 rs2280788 impact the baseline chemokine values Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: 3.7. CCR2 rs1799864 and CCR5-Delta32 determine the chemokine concentration in INR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: 4. DISCUSSION Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Data availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3 Item: Title: Declaration of Competing interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@32eebfca Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d Info: Title: High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients Author: Elena Yeregui Subject: EBioMedicine, 62 (2020) 103077. doi:10.1016/j.ebiom.2020.103077 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doi:10.1016/j.ebiom.2020.103077 Elsevier B.V. EBioMedicine, 62 (2020) 103077. doi:10.1016/j.ebiom.2020.103077 Chemokines Chemokine receptors HIV Poor immune recovery Polymorphisms variants High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients Elena Yeregui Consuelo Viladés Pere Domingo Andra Ceausu Yolanda María Pacheco Sergi Veloso Alexy Inciarte Judit Vidal-González Maria Peraire Carles Perpiñán Vicenç Falcó Jenifer Masip Verónica Alba Montserrat Vargas Anna Martí Laia Reverté Josep Mallolas Francesc Vidal Joaquim Peraire Anna Rull uuid:fd8cfc10-4791-4a8b-8025-00abb91efa0c uuid:8dc60b7e-c4f7-4615-b0c1-f1efcf468bb6 journal © 2020 The Authors. Published by Elsevier B.V. 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Subtype: Link Rect: 326, 376, 562, 383 Annotation: Subtype: Link Rect: 326, 368, 562, 375 Annotation: Subtype: Link Rect: 326, 360, 381, 367 Checksum: 49f42e2f Type: CRC32 Checksum: f4d38e8ceda3a654cd8a6fc9263fe65b Type: MD5 Checksum: 0cc4fca368e4d0b4fa71fbb5255d5fd2b3fc169d Type: SHA-1