ad2d55cc9969c06242c35ebe50be57d8 284624.pdf 86cab033da54f1653940bc3daf3eb592a58de773 284624.pdf 275588858ecfdc94f72b1b47c9454481d054ebbc928dd8924787c12356aa3205 284624.pdf Title: Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS Subject: Journal of Hepatology, 73 (2020) 1082-1091. doi:10.1016/j.jhep.2020.04.024 Author: Jonel Trebicka Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: 1th October 2020 ModDate: Sun Oct 4 13:16:10 2020 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 785979 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- JAAJKM+AdvOTb83ee1dd.B Type 1C WinAnsi yes yes no 615 0 JAAJKN+AdvOT863180fb Type 1C WinAnsi yes yes no 616 0 FMDHBL+ArialMT Type 1C Custom yes yes yes 622 0 FMDIJF+Arial-BoldMT Type 1C WinAnsi yes yes no 623 0 JAAKAP+AdvP4C4E74 Type 1C Custom yes yes no 628 0 JAAJMA+AdvOT863180fb+fb Type 1C Custom yes yes yes 629 0 FMDGMK+AdvPS3FDD77 Type 1C WinAnsi yes yes no 634 0 JAAJKO+AdvOT863180fb+20 Type 1C WinAnsi yes yes no 635 0 JAAJKM+AdvOTb83ee1dd.B Type 1C WinAnsi yes yes no 398 0 JAAJKN+AdvOT863180fb Type 1C WinAnsi yes yes no 428 0 JAAJKO+AdvOT863180fb+20 Type 1C WinAnsi yes yes no 417 0 JAAJLO+AdvOTb92eb7df.I Type 1C WinAnsi yes yes no 411 0 JAAJLP+AdvOTb92eb7df.I+20 Type 1C WinAnsi yes yes no 432 0 JAAJMA+AdvOT863180fb+fb Type 1C Custom yes yes yes 401 0 JAAKAP+AdvP4C4E74 Type 1C WinAnsi yes yes no 397 0 JAAKIN+AdvOT863180fb+22 Type 1C Custom yes yes no 439 0 JAAKIO+AdvOT404f8e91.BI Type 1C WinAnsi yes yes no 435 0 JAAKKP+ArialMT Type 1C WinAnsi yes yes no 444 0 JAAKLA+Arial-ItalicMT Type 1C WinAnsi yes yes no 442 0 JAAKMA+Arial-BoldMT Type 1C WinAnsi yes yes no 449 0 JAALDO+AdvOTb83ee1dd.B+fb Type 1C Custom yes yes yes 450 0 JAALFO+AdvOTb83ee1dd.B+20 Type 1C WinAnsi yes yes no 451 0 JAALIO+AdvOTb92eb7df.I+fb Type 1C Custom yes yes yes 452 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-11-16 02:38:53 CET RepresentationInformation: 284624.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-11-15 13:44:24 CET Size: 785979 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Improperly formed date Offset: 773806 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff10' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff11' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff12' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff13' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff14' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff16' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff17' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff18' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff19' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff20' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff21' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff22' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff23' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff24' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff25' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff26' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff27' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff28' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff29' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff30' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff31' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff32' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff33' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff34' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff35' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff36' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff37' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff38' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff39' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff40' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff40' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff40' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff18' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff17' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff16' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff14' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff13' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff12' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff11' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff41' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff24' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff42' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff40' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff43' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib16' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib18' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib19' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib20' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib21' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib22' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib21' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib24' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib10' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib25' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 755427 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib25' cannot be found Offset: 755427 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 681 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Patients and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Children: Item: Title: Study design and patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Data management and statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: Baseline characteristics and the prevalence of ACLF at admission in patients with AVB Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: ACLF as an independent risk factor of 42-day and 1-year rebleeding and mortality in patents with AVB Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Impact of pre-emptive TIPS on rebleeding rate and mortality in patients with AVB, with or without ACLF Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Children: Item: Title: Abbreviations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Financial support Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Conflict of interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Authors' contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Supplementary data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Info: Title: Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS Author: Jonel Trebicka Subject: Journal of Hepatology, 73 (2020) 1082-1091. doi:10.1016/j.jhep.2020.04.024 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) ID: 0x10c60da3b76aa2ac4ebb5049d251c238, 0x91fee40238727d40bc6399864f82e255 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: JAAJKO+AdvOT863180fb+20 FontSubset: true FirstChar: 134 LastChar: 150 FontDescriptor: FontName: JAAJKO+AdvOT863180fb+20 Flags: Nonsymbolic FontBBox: 9, -208, 947, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAKMA+Arial-BoldMT FontSubset: true FirstChar: 65 LastChar: 69 FontDescriptor: FontName: JAAKMA+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAALDO+AdvOTb83ee1dd.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JAALDO+AdvOTb83ee1dd.B+fb Flags: Symbolic FontBBox: 19, 0, 947, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JAALFO+AdvOTb83ee1dd.B+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: JAALFO+AdvOTb83ee1dd.B+20 Flags: Nonsymbolic FontBBox: 9, -208, 1125, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAALIO+AdvOTb92eb7df.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JAALIO+AdvOTb92eb7df.I+fb Flags: Symbolic FontBBox: -114, -208, 833, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JAAJKM+AdvOTb83ee1dd.B FontSubset: true FirstChar: 44 LastChar: 122 FontDescriptor: FontName: JAAJKM+AdvOTb83ee1dd.B Flags: Serif, Nonsymbolic FontBBox: -93, -250, 1041, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAJKN+AdvOT863180fb FontSubset: true FirstChar: 37 LastChar: 248 FontDescriptor: FontName: JAAJKN+AdvOT863180fb Flags: Serif, Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAJKN+AdvOT863180fb FontSubset: true FirstChar: 35 LastChar: 243 FontDescriptor: FontName: JAAJKN+AdvOT863180fb Flags: Serif, Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAKAP+AdvP4C4E74 FontSubset: true FirstChar: 106 LastChar: 106 FontDescriptor: FontName: JAAKAP+AdvP4C4E74 Flags: Nonsymbolic FontBBox: -20, -958, 1114, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMDHBL+ArialMT FontSubset: true FirstChar: 2 LastChar: 177 FontDescriptor: FontName: FMDHBL+ArialMT Flags: Symbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JAAJKM+AdvOTb83ee1dd.B FontSubset: true FirstChar: 37 LastChar: 121 FontDescriptor: FontName: JAAJKM+AdvOTb83ee1dd.B Flags: Serif, Nonsymbolic FontBBox: -93, -250, 1041, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMDIJF+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: FMDIJF+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAJLP+AdvOTb92eb7df.I+20 FontSubset: true FirstChar: 146 LastChar: 148 FontDescriptor: FontName: JAAJLP+AdvOTb92eb7df.I+20 Flags: Nonsymbolic FontBBox: -41, -208, 885, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAJMA+AdvOT863180fb+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: JAAJMA+AdvOT863180fb+fb Flags: Symbolic FontBBox: 40, 0, 895, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JAAKIO+AdvOT404f8e91.BI FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: JAAKIO+AdvOT404f8e91.BI Flags: Nonsymbolic FontBBox: -166, -239, 1114, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAKAP+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JAAKAP+AdvP4C4E74 Flags: Nonsymbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: JAAJMA+AdvOT863180fb+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: JAAJMA+AdvOT863180fb+fb Flags: Symbolic FontBBox: 40, 0, 895, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JAAKIN+AdvOT863180fb+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: JAAKIN+AdvOT863180fb+22 Flags: Nonsymbolic FontBBox: -20, -208, 770, 885 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: FMDGMK+AdvPS3FDD77 FontSubset: true FirstChar: 46 LastChar: 46 FontDescriptor: FontName: FMDGMK+AdvPS3FDD77 Flags: Nonsymbolic FontBBox: 0, -208, 1145, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAKLA+Arial-ItalicMT FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: JAAKLA+Arial-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAJKO+AdvOT863180fb+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: JAAJKO+AdvOT863180fb+20 Flags: Nonsymbolic FontBBox: 9, -208, 947, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAJLO+AdvOTb92eb7df.I FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: JAAJLO+AdvOTb92eb7df.I Flags: Serif, Nonsymbolic FontBBox: -135, -229, 1052, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JAAKKP+ArialMT FontSubset: true FirstChar: 32 LastChar: 176 FontDescriptor: FontName: JAAKKP+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.jhep.2020.04.024 Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS Jonel Trebicka Wenyi Gu Luis Ibáñez-Samaniego Virginia Hernández-Gea Carla Pitarch Elisabet Garcia Bogdan Procopet Álvaro Giráldez Lucio Amitrano Candid Villanueva Dominique Thabut Gilberto Silva-Junior Javier Martinez Joan Genescà Cristophe Bureau Elba Llop Wim Laleman Jose Maria Palazon Jose Castellote Susanag Rodrigues Liselotte Gluud Carlos Noronha Ferreira Rafael Barcelo Nuria Cañete Manuel Rodríguez Arnulf Ferlitsch Jose Luis Mundi Henning Gronbaek Manuel Hernández-Guerra Romano Sassatelli Alessandra Dell'Era Marco Senzolo Juan G. Abraldes Manuel Romero-Gómez Alexander Zipprich Meritxell Casas Helena Masnou Massimo Primignani Emmanuel Weiss Maria-Vega Catalina Hans-Peter Erasmus Frank Erhard Uschner Martin Schulz Maximilian J. Brol Michael Praktiknjo Johannes Chang Aleksander Krag Frederik Nevens Jose Luis Calleja Marie Angèle Robic Irene Conejo Agustin Albillos Marika Rudler Edilmar Alvarado Maria Anna Guardascione Marcel Tantau Jaime Bosch Ferran Torres Marco Pavesi Juan Carlos Garcia-Pagán Christian Jansen Rafael Bañares International Variceal Bleeding Observational Study Group and Baveno Cooperation Acute variceal bleeding Acute-on-chronic liver failure Cirrhosis Rebleeding Journal of Hepatology, 73 (2020) 1082-1091. doi:10.1016/j.jhep.2020.04.024 Elsevier B.V journal Journal of Hepatology © 2020 European Association for the Study of the Liver. Published by Elsevier B.V. 0168-8278 73 5 November 2020 1082-1091 1082 1091 10.1016/j.jhep.2020.04.024 https://doi.org/10.1016/j.jhep.2020.04.024 2010-04-23 true 10.1016/j.jhep.2020.04.024 elsevier.com sciencedirect.com VoR 7.0 10.1016/j.jhep.2020.04.024 noindex 2010-04-23 true 1th October 2020 sciencedirect.com elsevier.com Elsevier 2020-10-04T16:46:10+05:30 2020-10-04T16:46:10+05:30 True 1th October 2020 Acrobat Distiller 8.1.0 (Windows) uuid:812caa31-2c99-40c9-a622-cb9c7e5970fa uuid:fbec2668-0262-4e12-a8cb-825196cd4c9d http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1082 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 369, 514, 468, 524 Annotation: Subtype: Link Rect: 42, 45, 193, 53 Annotation: Subtype: Link Rect: 45, 25, 230, 33 Annotation: Subtype: Link Rect: 232, 777, 232, 777 Page: Label: 1083 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 142, 655, 147, 666 Destination: 1 Annotation: Subtype: Link Rect: 148, 655, 153, 666 Destination: 1 Annotation: Subtype: Link Rect: 155, 655, 159, 666 Destination: 1 Annotation: Subtype: Link Rect: 161, 655, 166, 666 Destination: 1 Annotation: Subtype: Link Rect: 174, 655, 178, 666 Destination: 1 Annotation: Subtype: Link Rect: 233, 655, 238, 666 Destination: 1 Annotation: Subtype: Link Rect: 239, 655, 244, 666 Destination: 1 Annotation: Subtype: Link Rect: 246, 655, 251, 666 Destination: 1 Annotation: Subtype: Link Rect: 253, 655, 256, 666 Destination: 1 Annotation: Subtype: Link Rect: 378, 655, 382, 666 Destination: 1 Annotation: Subtype: Link Rect: 510, 655, 514, 666 Destination: 1 Annotation: Subtype: Link Rect: 515, 655, 520, 666 Destination: 1 Annotation: Subtype: Link Rect: 144, 642, 148, 653 Destination: 1 Annotation: Subtype: Link Rect: 228, 642, 233, 653 Destination: 1 Annotation: Subtype: Link Rect: 324, 642, 329, 653 Destination: 1 Annotation: Subtype: Link Rect: 412, 642, 421, 653 Destination: null Annotation: Subtype: Link Rect: 504, 642, 513, 653 Destination: null Annotation: Subtype: Link Rect: 178, 629, 182, 640 Destination: 1 Annotation: Subtype: Link Rect: 184, 629, 193, 640 Destination: null Annotation: Subtype: Link Rect: 293, 629, 302, 640 Destination: null Annotation: Subtype: Link Rect: 410, 629, 414, 640 Destination: 1 Annotation: Subtype: Link Rect: 496, 629, 505, 640 Destination: null Annotation: Subtype: Link Rect: 140, 616, 145, 627 Destination: 1 Annotation: Subtype: Link Rect: 147, 616, 155, 627 Destination: null Annotation: Subtype: Link Rect: 248, 616, 257, 627 Destination: null Annotation: Subtype: Link Rect: 309, 616, 314, 627 Destination: 1 Annotation: Subtype: Link Rect: 316, 616, 324, 627 Destination: null Annotation: Subtype: Link Rect: 399, 616, 408, 627 Destination: null Annotation: Subtype: Link Rect: 509, 616, 518, 627 Destination: null Annotation: Subtype: Link Rect: 160, 603, 169, 614 Destination: null Annotation: Subtype: Link Rect: 269, 603, 278, 614 Destination: null Annotation: Subtype: Link Rect: 359, 603, 369, 614 Destination: null Annotation: Subtype: Link Rect: 495, 603, 504, 614 Destination: null Annotation: Subtype: Link Rect: 139, 590, 148, 601 Destination: null Annotation: Subtype: Link Rect: 219, 590, 229, 601 Destination: null Annotation: Subtype: Link Rect: 327, 590, 336, 601 Destination: null Annotation: Subtype: Link Rect: 420, 590, 429, 601 Destination: null Annotation: Subtype: Link Rect: 514, 590, 523, 601 Destination: null Annotation: Subtype: Link Rect: 211, 577, 221, 588 Destination: null Annotation: Subtype: Link Rect: 361, 577, 371, 588 Destination: null Annotation: Subtype: Link Rect: 467, 577, 476, 588 Destination: null Annotation: Subtype: Link Rect: 175, 564, 184, 575 Destination: null Annotation: Subtype: Link Rect: 264, 564, 273, 575 Destination: null Annotation: Subtype: Link Rect: 362, 564, 372, 575 Destination: null Annotation: Subtype: Link Rect: 497, 564, 502, 575 Destination: 1 Annotation: Subtype: Link Rect: 504, 564, 513, 575 Destination: null Annotation: Subtype: Link Rect: 188, 551, 197, 562 Destination: null Annotation: Subtype: Link Rect: 279, 551, 289, 562 Destination: null Annotation: Subtype: Link Rect: 372, 551, 381, 562 Destination: null Annotation: Subtype: Link Rect: 491, 551, 500, 562 Destination: null Annotation: Subtype: Link Rect: 166, 538, 170, 549 Destination: 1 Annotation: Subtype: Link Rect: 278, 538, 282, 549 Destination: 1 Annotation: Subtype: Link Rect: 390, 538, 394, 549 Destination: 1 Annotation: Subtype: Link Rect: 509, 538, 514, 549 Destination: 1 Annotation: Subtype: Link Rect: 173, 525, 178, 536 Destination: 1 Annotation: Subtype: Link Rect: 273, 525, 283, 536 Destination: null Annotation: Subtype: Link Rect: 383, 525, 393, 536 Destination: null Annotation: Subtype: Link Rect: 479, 525, 489, 536 Destination: null Annotation: Subtype: Link Rect: 180, 512, 185, 523 Destination: 1 Annotation: Subtype: Link Rect: 272, 512, 281, 523 Destination: null Annotation: Subtype: Link Rect: 367, 512, 372, 523 Destination: 1 Annotation: Subtype: Link Rect: 374, 512, 382, 523 Destination: null Annotation: Subtype: Link Rect: 485, 512, 494, 523 Destination: null Annotation: Subtype: Link Rect: 173, 499, 178, 510 Destination: 1 Annotation: Subtype: Link Rect: 180, 499, 188, 510 Destination: null Annotation: Subtype: Link Rect: 273, 499, 278, 510 Destination: 1 Annotation: Subtype: Link Rect: 280, 499, 288, 510 Destination: null Annotation: Subtype: Link Rect: 366, 499, 374, 510 Destination: null Annotation: Subtype: Link Rect: 467, 499, 472, 510 Destination: 1 Annotation: Subtype: Link Rect: 474, 499, 483, 510 Destination: null Annotation: Subtype: Link Rect: 226, 486, 234, 497 Destination: null Annotation: Subtype: Link Rect: 311, 486, 316, 497 Destination: 1 Annotation: Subtype: Link Rect: 382, 486, 387, 497 Destination: 1 Annotation: Subtype: Link Rect: 388, 486, 393, 497 Destination: 1 Annotation: Subtype: Link Rect: 395, 486, 404, 497 Destination: null Annotation: Subtype: Link Rect: 475, 486, 485, 497 Destination: null Annotation: Subtype: Link Rect: 487, 486, 496, 497 Destination: null Annotation: Subtype: Link Rect: 135, 474, 140, 485 Destination: 1 Annotation: Subtype: Link Rect: 271, 474, 276, 485 Destination: 1 Annotation: Subtype: Link Rect: 277, 474, 282, 485 Destination: 1 Annotation: Subtype: Link Rect: 369, 474, 379, 485 Destination: null Annotation: Subtype: Link Rect: 381, 474, 384, 485 Destination: 1 Annotation: Subtype: Link Rect: 463, 474, 468, 485 Destination: 1 Annotation: Subtype: Link Rect: 470, 474, 479, 485 Destination: null Annotation: Subtype: Link Rect: 481, 474, 485, 485 Destination: 1 Annotation: Subtype: Link Rect: 349, 130, 414, 136 Annotation: Subtype: Link Rect: 303, 113, 426, 119 Annotation: Subtype: Link Rect: 283, 737, 311, 765 Page: Label: 1084 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 72, 203, 257, 210 Annotation: Subtype: Link Rect: 250, 157, 253, 165 Destination: 221 Annotation: Subtype: Link Rect: 189, 135, 193, 143 Destination: 221 Annotation: Subtype: Link Rect: 128, 102, 132, 111 Destination: 221 Annotation: Subtype: Link Rect: 133, 102, 137, 111 Destination: 221 Annotation: Subtype: Link Rect: 200, 69, 203, 78 Destination: 221 Annotation: Subtype: Link Rect: 346, 577, 349, 586 Destination: 221 Annotation: Subtype: Link Rect: 351, 577, 354, 586 Destination: 221 Annotation: Subtype: Link Rect: 356, 577, 359, 586 Destination: 221 Annotation: Subtype: Link Rect: 354, 533, 357, 542 Destination: 221 Annotation: Subtype: Link Rect: 484, 511, 488, 520 Destination: 221 Annotation: Subtype: Link Rect: 489, 511, 503, 520 Destination: 221 Annotation: Subtype: Link Rect: 474, 490, 480, 498 Destination: null Annotation: Subtype: Link Rect: 525, 446, 532, 454 Destination: null Annotation: Subtype: Link Rect: 514, 413, 521, 421 Destination: null Annotation: Subtype: Link Rect: 416, 391, 423, 399 Destination: null Annotation: Subtype: Link Rect: 424, 391, 431, 399 Destination: null Annotation: Subtype: Link Rect: 419, 380, 426, 388 Destination: null Annotation: Subtype: Link Rect: 427, 380, 433, 388 Destination: null Annotation: Subtype: Link Rect: 412, 190, 419, 198 Destination: null Annotation: Subtype: Link Rect: 373, 168, 380, 176 Destination: null Annotation: Subtype: Link Rect: 328, 124, 331, 132 Destination: 221 Page: Label: 1085 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 186, 180, 193, 188 Destination: null Page: Label: 1086 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 422, 142, 451, 151 Destination: 144 Page: Label: 1087 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 409, 602, 429, 611 Destination: 150 Annotation: Subtype: Link Rect: 326, 515, 346, 523 Destination: 150 Annotation: Subtype: Link Rect: 364, 515, 392, 523 Destination: 161 Annotation: Subtype: Link Rect: 408, 482, 429, 490 Destination: 173 Annotation: Subtype: Link Rect: 306, 449, 328, 458 Destination: 173 Annotation: Subtype: Link Rect: 347, 449, 376, 458 Destination: 161 Annotation: Subtype: Link Rect: 364, 296, 392, 304 Destination: 189 Annotation: Subtype: Link Rect: 496, 252, 520, 260 Destination: 199 Annotation: Subtype: Link Rect: 412, 197, 433, 205 Destination: 213 Annotation: Subtype: Link Rect: 442, 131, 464, 140 Destination: 213 Page: Label: 1088 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 110, 153, 130, 161 Destination: 213 Annotation: Subtype: Link Rect: 315, 277, 321, 286 Destination: null Annotation: Subtype: Link Rect: 323, 266, 330, 275 Destination: null Annotation: Subtype: Link Rect: 331, 266, 338, 275 Destination: null Annotation: Subtype: Link Rect: 512, 157, 519, 165 Destination: null Annotation: Subtype: Link Rect: 520, 157, 527, 165 Destination: null Page: Label: 1089 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 136, 202, 142, 211 Destination: null Annotation: Subtype: Link Rect: 62, 126, 69, 134 Destination: null Annotation: Subtype: Link Rect: 70, 126, 77, 134 Destination: null Annotation: Subtype: Link Rect: 78, 126, 86, 134 Destination: null Annotation: Subtype: Link Rect: 276, 115, 283, 123 Destination: null Annotation: Subtype: Link Rect: 284, 115, 291, 123 Destination: null Annotation: Subtype: Link Rect: 285, 104, 291, 112 Destination: null Annotation: Subtype: Link Rect: 503, 158, 510, 167 Destination: null Page: Label: 1090 Sequence: 9 Page: Label: 1091 Sequence: 10 Page: Label: 1092 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 263, 517, 291, 525 Annotation: Subtype: Link Rect: 42, 506, 175, 514 Annotation: Subtype: Link Rect: 58, 453, 291, 460 Annotation: Subtype: Link Rect: 58, 444, 291, 451 Annotation: Subtype: Link Rect: 58, 436, 291, 442 Annotation: Subtype: Link Rect: 58, 427, 291, 433 Annotation: Subtype: Link Rect: 58, 418, 291, 425 Annotation: Subtype: Link Rect: 58, 409, 70, 416 Annotation: Subtype: Link Rect: 58, 400, 291, 407 Annotation: Subtype: Link Rect: 58, 391, 291, 398 Annotation: Subtype: Link Rect: 58, 382, 260, 389 Annotation: Subtype: Link Rect: 58, 373, 291, 380 Annotation: Subtype: Link Rect: 58, 364, 243, 371 Annotation: Subtype: Link Rect: 58, 355, 291, 362 Annotation: Subtype: Link Rect: 58, 346, 262, 353 Annotation: Subtype: Link Rect: 58, 337, 291, 344 Annotation: Subtype: Link Rect: 58, 328, 291, 335 Annotation: Subtype: Link Rect: 58, 319, 142, 326 Annotation: Subtype: Link Rect: 58, 310, 291, 317 Annotation: Subtype: Link Rect: 58, 301, 275, 308 Annotation: Subtype: Link Rect: 58, 292, 291, 299 Annotation: Subtype: Link Rect: 58, 283, 291, 290 Annotation: Subtype: Link Rect: 58, 274, 291, 281 Annotation: Subtype: Link Rect: 58, 265, 79, 272 Annotation: Subtype: Link Rect: 58, 256, 291, 263 Annotation: Subtype: Link Rect: 58, 247, 291, 254 Annotation: Subtype: Link Rect: 58, 238, 224, 245 Annotation: Subtype: Link Rect: 319, 725, 552, 732 Annotation: Subtype: Link Rect: 319, 716, 552, 723 Annotation: Subtype: Link Rect: 319, 707, 452, 714 Annotation: Subtype: Link Rect: 319, 698, 552, 705 Annotation: Subtype: Link Rect: 319, 689, 552, 696 Annotation: Subtype: Link Rect: 319, 680, 552, 687 Annotation: Subtype: Link Rect: 319, 671, 398, 678 Annotation: Subtype: Link Rect: 319, 662, 552, 669 Annotation: Subtype: Link Rect: 319, 653, 552, 660 Annotation: Subtype: Link Rect: 319, 644, 552, 651 Annotation: Subtype: Link Rect: 319, 635, 382, 642 Annotation: Subtype: Link Rect: 319, 626, 552, 633 Annotation: Subtype: Link Rect: 319, 617, 552, 624 Annotation: Subtype: Link Rect: 319, 608, 552, 615 Annotation: Subtype: Link Rect: 319, 599, 511, 606 Annotation: Subtype: Link Rect: 319, 590, 552, 597 Annotation: Subtype: Link Rect: 319, 581, 552, 588 Annotation: Subtype: Link Rect: 319, 572, 523, 579 Annotation: Subtype: Link Rect: 319, 563, 552, 570 Annotation: Subtype: Link Rect: 319, 554, 552, 561 Annotation: Subtype: Link Rect: 319, 545, 334, 552 Annotation: Subtype: Link Rect: 319, 536, 552, 543 Annotation: Subtype: Link Rect: 319, 527, 552, 534 Annotation: Subtype: Link Rect: 319, 518, 552, 525 Annotation: Subtype: Link Rect: 319, 509, 369, 516 Annotation: Subtype: Link Rect: 319, 500, 552, 507 Annotation: Subtype: Link Rect: 319, 491, 511, 498 Annotation: Subtype: Link Rect: 319, 482, 552, 489 Annotation: Subtype: Link Rect: 319, 473, 552, 480 Annotation: Subtype: Link Rect: 319, 464, 552, 471 Annotation: Subtype: Link Rect: 319, 456, 409, 463 Annotation: Subtype: Link Rect: 319, 447, 552, 454 Annotation: Subtype: Link Rect: 319, 438, 538, 445 Annotation: Subtype: Link Rect: 319, 429, 552, 436 Annotation: Subtype: Link Rect: 319, 420, 552, 427 Annotation: Subtype: Link Rect: 319, 411, 482, 418 Annotation: Subtype: Link Rect: 319, 402, 552, 409 Annotation: Subtype: Link Rect: 319, 393, 487, 400 Annotation: Subtype: Link Rect: 319, 384, 552, 391 Annotation: Subtype: Link Rect: 319, 375, 552, 382 Annotation: Subtype: Link Rect: 319, 366, 375, 373 Annotation: Subtype: Link Rect: 319, 357, 552, 364 Annotation: Subtype: Link Rect: 319, 348, 552, 355 Annotation: Subtype: Link Rect: 319, 339, 552, 346 Annotation: Subtype: Link Rect: 319, 330, 404, 337 Annotation: Subtype: Link Rect: 319, 321, 552, 328 Annotation: Subtype: Link Rect: 319, 312, 552, 319 Annotation: Subtype: Link Rect: 319, 303, 523, 310 Annotation: Subtype: Link Rect: 319, 294, 552, 301 Annotation: Subtype: Link Rect: 319, 285, 552, 292 Annotation: Subtype: Link Rect: 319, 276, 552, 283 Annotation: Subtype: Link Rect: 319, 267, 402, 274 Annotation: Subtype: Link Rect: 319, 258, 552, 265 Annotation: Subtype: Link Rect: 319, 249, 552, 256 Annotation: Subtype: Link Rect: 319, 240, 540, 247 Checksum: 3dff2df4 Type: CRC32 Checksum: ad2d55cc9969c06242c35ebe50be57d8 Type: MD5 Checksum: 86cab033da54f1653940bc3daf3eb592a58de773 Type: SHA-1