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Actualización 2020 Subject: Open Respiratory Archives, 2 (2020) 158-174. doi:10.1016/j.opresp.2020.03.005 Keywords: Asma grave; Asma grave; Diagnóstico; Seguimiento; Tratamiento; Anticuerpos monoclonales Author: Francisco Javier Álvarez-Gutiérrez Creator: Elsevier Producer: Acrobat Distiller 9.0.0 (Windows) CreationDate: Wed Sep 16 20:54:54 2020 CEST ModDate: Mon Sep 21 13:18:29 2020 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.28 x 793.7 pts Page rot: 0 File size: 819632 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LOHMFF+GulliverRM Type 1C Custom yes yes yes 1081 0 LOHMFG+Times-Roman Type 1C WinAnsi yes yes no 1083 0 LOHMGH+GulliverBL Type 1C Custom yes yes yes 1086 0 LOHMGI+DIN-CondensedBoldA Type 1C Custom yes yes yes 1089 0 LOHMJH+Univers Type 1C Custom yes yes yes 1092 0 LOHMMH+OnemtmiguAAAA Type 1C Custom yes yes yes 1095 0 LOHMMI+MTSY Type 1C Custom yes yes yes 1098 0 LOHMNJ+GulliverIT Type 1C Custom yes yes yes 1101 0 LOHNGG+GulliverSCOsF Type 1C Custom yes yes yes 1104 0 LOHPDL+GulliverBI Type 1C Custom yes yes yes 647 0 LOIBHN+OneGulliverA Type 1C Custom yes yes yes 644 0 LOICMG+MATHG-1A Type 1C Custom yes yes no 641 0 LOIPLC+Helvetica Type 1C WinAnsi yes yes no 651 0 LOJJOA+Helvetica-Light Type 1C WinAnsi yes yes no 656 0 LOJJPB+Symbol Type 1C Custom yes yes yes 655 0 LOJJPC+Helvetica-Oblique Type 1C WinAnsi yes yes no 654 0 LOJKDB+Haettenschweiler Type 1C Custom yes yes yes 653 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-06-21 02:51:07 CEST RepresentationInformation: 293978.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-06-17 17:04:19 CEST Size: 819632 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Documento de consenso de asma grave en adultos. Actualización 2020 Destination: 1 Children: Item: Title: Metodología Destination: 1 Item: Title: Diagnóstico del asma grave Destination: 1 Children: Item: Title: Definición Destination: 1 Item: Title: Fenotipos en asma grave Destination: 1 Item: Title: Epidemiología Destination: 1 Children: Item: Title: Requisitos mínimos para un correcto diagnóstico Destination: 1 Item: Title: Seguimiento del asma grave Destination: 1 Children: Item: Title: Introducción Destination: 1 Item: Title: Indicadores de la situación del paciente Destination: 1 Item: Title: Indicadores de cumplimiento del tratamiento Destination: 1 Item: Title: Indicadores para establecer el pronóstico Destination: 1 Item: Title: Marcadores de planificación del ajuste terapéutico Destination: 1 Item: Title: Tratamiento del asma grave Destination: 1 Children: Item: Title: Introducción Destination: 1 Item: Title: Tratamiento farmacológico de base Destination: 1 Item: Title: Tratamiento de las comorbilidades Destination: 1 Item: Title: Tratamiento de los efectos secundarios de los glucocorticoides Destination: 1 Item: Title: Educación sanitaria en asma Destination: 1 Item: Title: Otros tratamientos para el asma grave Destination: 1 Children: Item: Title: Macrólidos Destination: 1 Item: Title: Termoplastia Destination: 1 Item: Title: Glucocorticoides orales Destination: 1 Item: Title: Anticuerpos monoclonales Destination: 1 Item: Title: Anticuerpos monoclonales disponibles actualmente Destination: 1 Children: Item: Title: Omalizumab Destination: 1 Item: Title: Mepolizumab Destination: 1 Item: Title: Reslizumab Destination: 1 Item: Title: Benralizumab Destination: 1 Item: Title: Dupilumab Destination: 1 Item: Title: Cambio de anticuerpo monoclonal en pacientes poco o no respondedores a un anticuerpo determinado Destination: 1 Item: Title: Medidas preventivas en asma Destination: 1 Children: Item: Title: Medidas de control ambiental Destination: 1 Children: Item: Title: Evitar el tabaquismo activo y pasivo Destination: 1 Item: Title: Contaminación ambiental Destination: 1 Item: Title: Antiinflamatorios no esteroideos Destination: 1 Item: Title: Alérgenos Destination: 1 Item: Title: Vacunación antigripal Destination: 1 Item: Title: Vacunación antineumocócica Destination: 1 Item: Title: Conflicto de intereses Destination: 1 Item: Title: Agradecimientos Destination: 1 Item: Title: Anexo 1 Participantes del Grupo Validador de Recomendaciones, nombrados por las sociedades autonómicas y el área de asma d... 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Actualización 2020 Francisco Javier Álvarez-Gutiérrez Marina Blanco-Aparicio Vicente Plaza Carolina Cisneros Juan Luis García-Rivero Alicia Padilla Luis Pérez-de Llano Miguel Perpiñá Gregorio Soto-Campos Open Respiratory Archives, 2 (2020) 158-174. doi:10.1016/j.opresp.2020.03.005 Sociedad Española de Neumología y Cirugía Torácica (SEPAR) Asma grave Asma grave Diagnóstico Seguimiento Tratamiento Anticuerpos monoclonales journal Open Respiratory Archives © 2020 Publicado por Elsevier España, S.L.U. Todos los derechos reservados. 2659-6636 2 3 July-September 2020 158-174 158 174 10.1016/j.opresp.2020.03.005 https://doi.org/10.1016/j.opresp.2020.03.005 2010-04-23 true 10.1016/j.opresp.2020.03.005 elsevier.com sciencedirect.com VoR 10.1016/j.opresp.2020.03.005 noindex 2010-04-23 true sciencedirect.com elsevier.com sciencedirect.com elsevier.com Elsevier 2020-09-16T18:54:54Z 2020-09-21T16:48:29+05:30 2020-09-21T16:48:29+05:30 True Unknown Acrobat Distiller 9.0.0 (Windows) Asma grave; Asma grave; Diagnóstico; Seguimiento; Tratamiento; Anticuerpos monoclonales uuid:29d87dae-ed45-4887-b2e3-7e6859df8c39 uuid:da772740-ac16-474c-ab1f-d0e7b3ac136c http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 276, 798, 392, 803 Flags: Print Annotation: Subtype: Link Rect: 300, 715, 395, 720 Flags: Print Annotation: Subtype: Link Rect: 538, 645, 567, 674 Flags: Print Annotation: Subtype: Link Rect: 246, 643, 265, 650 Flags: Print 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