2b1442cb023e7a3be89075dedf6908b4 pmc_32807790.pdf cef9c96f37a8c3e2bd36a4b78a93c4aab3088066 pmc_32807790.pdf 93d2e08be1244c8c76166204a556f1fb2f1f81b3d32c034baed7ee4e3bc26b99 pmc_32807790.pdf Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13 Subject: Nature Communications, doi:10.1038/s41467-020-17901-2 Keywords: Author: Patricia R. Pitrez Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Mon Aug 10 14:14:20 2020 CEST ModDate: Tue Aug 11 11:17:22 2020 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 3866083 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- OPIBJA+AdvOTf23bb480+20 Type 1C WinAnsi yes yes no 887 0 OPIBGO+AdvOTcb88df00 Type 1C WinAnsi yes yes no 75 0 OPIBJB+AdvTTda6f6cb8.B Type 1C WinAnsi yes yes no 76 0 Arial-BoldMT Type 1C WinAnsi yes no no 888 0 OPIBIP+AdvOTf23bb480 Type 1C WinAnsi yes yes no 889 0 OPHPPB+AdvOTea1a7398 Type 1C WinAnsi yes yes no 86 0 OPIBGJ+AdvTT2876772e+27 Type 1C Custom yes yes yes 890 0 OPIBGK+AdvOTea1a7398+fb Type 1C Custom yes yes yes 165 0 OPIBGL+AdvOT9bd21c25.I Type 1C WinAnsi yes yes no 166 0 OPIBGM+AdvTTab7e17fd+22 Type 1C Custom yes yes no 87 0 OPIBGN+AdvTTab7e17fd Type 1C WinAnsi yes yes no 88 0 OPIBNI+AdvOT1ef757c0+22 Type 1C Custom yes yes yes 77 0 OPIBNG+AdvOT7d6df7ab.I+03 Type 1C Custom yes yes yes 78 0 OPIBNH+AdvOT1ef757c0+03 Type 1C Custom yes yes yes 79 0 OPIBNE+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 80 0 OPIBNF+AdvOTb65e897d.B Type 1C WinAnsi yes yes no 81 0 OPIBMD+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 82 0 OPIBME+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 83 0 OPIBMB+AdvOT125c650c Type 1C WinAnsi yes yes no 84 0 OPIBMC+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 85 0 OPIIGB+Helvetica Type 1C WinAnsi yes yes no 116 0 OPIIKB+Helvetica-Oblique Type 1C WinAnsi yes yes no 117 0 OPIIKC+Symbol Type 1C Custom yes yes yes 118 0 OPIILC+Helvetica-Bold Type 1C WinAnsi yes yes no 119 0 OPIOPP+AdvOTea1a7398+20 Type 1C WinAnsi yes yes no 161 0 OPIPAA+AdvOT8608a8d1+03 Type 1C Custom yes yes yes 162 0 OPIOON+AdvOTb65e897d.B+fb Type 1C Custom yes yes yes 163 0 OPIOPO+AdvOTcb88df00+fb Type 1C Custom yes yes yes 164 0 Helvetica2 Type 1C WinAnsi yes no no 193 0 OPJKHN+AdvOT8608a8d1 Type 1C WinAnsi yes yes no 207 0 OPJIJH+AdvOT8b40f9c2.B+03 Type 1C Custom yes yes yes 208 0 OPJKHM+AdvOTe75a9404.I Type 1C WinAnsi yes yes no 209 0 OPJMBF+AdvOT45bf69de.BI Type 1C WinAnsi yes yes no 342 0 OPJMCF+AdvOT8608a8d1+22 Type 1C Custom yes yes yes 343 0 OPKIAO+AdvTT7b515deb Type 1C WinAnsi yes yes no 513 0 OPKIAN+AdvOT1ef757c0+21 Type 1C WinAnsi yes yes no 514 0 OPKIEO+AdvOTb65e897d.B+20 Type 1C WinAnsi yes yes no 564 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-06-22 02:31:10 CEST RepresentationInformation: pmc_32807790.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-08-31 03:36:03 CEST Size: 3866083 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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Pitrez Subject: Nature Communications, doi:10.1038/s41467-020-17901-2 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Mon Aug 10 14:44:20 CEST 2020 ModDate: Tue Aug 11 11:17:22 CEST 2020 ID: 0x5e0913927e4d672c3eb0b18ef4319e9a, 0xc5fea140dda563a6877fee1f692deffd Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 856 ImageHeight: 453 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 942 ImageHeight: 531 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 312 ImageHeight: 609 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg 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Pitrez Luís Estronca Luís Miguel Monteiro Guillem Colell Helena Vazão Deolinda Santinha Karim Harhouri Daniel Thornton Claire Navarro Anne-Laure Egesipe Tânia Carvalho Rodrigo L. Dos Santos Nicolas Lévy James C. Smith João Pedro de Magalhães Alessandro Ori Andreia Bernardo Annachiara De Sandre-Giovannoli Xavier Nissan Anna Rosell Lino Ferreira Springer US Nature Communications, doi:10.1038/s41467-020-17901-2 10.1038/s41467-020-17901-2 http://dx.doi.org/10.1038/s41467-020-17901-2 journal Nature Communications © 2020, The Author(s) 2041-1723 10.1038/s41467-020-17901-2 springer.com springerlink.com 2010-04-23 True 10.1038/s41467-020-17901-2 springer.com springerlink.com Springer 2020-08-11T11:17:22+02:00 2020-08-10T17:44:20+05:30 2020-08-11T11:17:22+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) VoR uuid:73f84742-3795-4d67-8802-d173c6ed8111 uuid:fef07482-5b23-4fc0-a206-178432925753 default 1 converted uuid:0461eecb-62e5-4470-8785-61cd776ac967 converted to PDF/A-2b pdfToolbox 2020-08-10T17:45:16+05:30 2 B Patricia R. Pitrez http://orcid.org/0000-0002-3116-0723 Luís Miguel Monteiro http://orcid.org/0000-0002-3325-8476 Deolinda Santinha http://orcid.org/0000-0001-8948-5232 Karim Harhouri http://orcid.org/0000-0003-2904-5221 Claire Navarro http://orcid.org/0000-0001-9490-2643 Tânia Carvalho http://orcid.org/0000-0002-5283-5013 James C. Smith http://orcid.org/0000-0003-2413-9392 Alessandro Ori http://orcid.org/0000-0002-3046-0871 Andreia Bernardo http://orcid.org/0000-0002-5355-6657 Annachiara De Sandre-Giovannoli http://orcid.org/0000-0002-2324-2462 Xavier Nissan http://orcid.org/0000-0003-3374-6274 Lino Ferreira http://orcid.org/0000-0001-8985-9302 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://crossref.org/crossmark/1.0/ crossmark crossmark internal CrossMarkDomains CrossMarkDomains Seq Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Usual same as prism:doi DOI Text external The date when a publication was published. MajorVersionDate Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Copyright copyright Text external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. issn Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url Text http://springernature.com/ns/xmpExtensions/2.0/ sn Springer Nature ORCID Schema external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. authorInfo Bag AuthorInformation Specifies the types of author information: name and ORCID of an author. http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author AuthorInformation Gives the name of an author. name Text Gives the ORCID of an author. orcid URI http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 473, 640, 475, 671 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 473, 643, 508, 674 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link 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