b083600ea5a1628823da4e171fe1ec43 pmc_33208850.pdf 6f706b1d8b8f64ff7d92ec8ca37ba9452726a731 pmc_33208850.pdf 6cc7cf08cfd49410d0b007d47015216466720f4da32ffe2f106e0badf6c16a58 pmc_33208850.pdf Title: Association of hyperuricemia and gamma glutamyl transferase as a marker of metabolic risk in alcohol use disorder Subject: Scientific Reports, https://doi.org/10.1038/s41598-020-77013-1 Author: Anna Hernández-Rubio Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu Nov 12 07:41:31 2020 CET ModDate: Thu Nov 12 09:54:54 2020 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 887911 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- QCWQCJ+Wingdings-Regular Type 1C WinAnsi yes yes yes 228 0 MinionPro-Regular Type 1C Custom yes no yes 41 0 XDOLGZ+Corbel-Bold CID TrueType Identity-H yes yes yes 44 0 Corbel2 TrueType WinAnsi yes no yes 45 0 SDFMOJ+Corbel CID TrueType Identity-H yes yes yes 46 0 SHSNOJ+MinionPro-Regular2 Type 1C Custom yes yes no 42 0 SHSNOJ+MinionPro-It Type 1C Custom yes yes no 43 0 SHSNOJ+MTMI Type 1C Custom yes yes no 47 0 SHSNOJ+MTSYN Type 1C Custom yes yes no 48 0 Corbel2 TrueType WinAnsi yes no yes 67 0 MinionPro-It2 Type 1C Custom yes no yes 105 0 MinionPro-Bold Type 1C Custom yes no yes 128 0 FKCOYO+MinionPro-BoldIt Type 1C WinAnsi yes yes yes 129 0 MOTKIV+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 148 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-22 02:42:37 CEST RepresentationInformation: pmc_33208850.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-11-23 03:35:56 CET Size: 887911 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 273 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Association of hyperuricemia and gamma glutamyl transferase as a marker of metabolic risk in alcohol use disorder Children: Item: Title: Methods Children: Item: Title: Statistical analysis. Item: Title: Results Item: Title: Discussion Item: Title: References Item: Title: Acknowledgements Info: Title: Association of hyperuricemia and gamma glutamyl transferase as a marker of metabolic risk in alcohol use disorder Author: Anna Hernández-Rubio Subject: Scientific Reports, https://doi.org/10.1038/s41598-020-77013-1 Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu Nov 12 08:11:31 CET 2020 ModDate: Thu Nov 12 09:54:54 CET 2020 ID: 0xa2234983f0d3dde26c867b38478b6d4c, 0x4dc999b1060cdef9b8d4dff318e8b1fa Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 833 ImageHeight: 542 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: XDOLGZ+Corbel-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: SDFMOJ+Corbel Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: SHSNOJ+MTSYN FontSubset: true FirstChar: 27 LastChar: 32 FontDescriptor: FontName: SHSNOJ+MTSYN Flags: Symbolic FontBBox: 0, -954, 873, 662 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MinionPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FKCOYO+MinionPro-BoldIt FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: FKCOYO+MinionPro-BoldIt Flags: Serif, Nonsymbolic, Italic FontBBox: -230, -360, 1684, 1032 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: QCWQCJ+Wingdings-Regular FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: QCWQCJ+Wingdings-Regular Flags: Nonsymbolic FontBBox: 0, -103, 1359, 439 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-It2 FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-It2 Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: SHSNOJ+MinionPro-Regular2 FontSubset: true FirstChar: 28 LastChar: 32 FontDescriptor: FontName: SHSNOJ+MinionPro-Regular2 Flags: Symbolic, AllCap FontBBox: 0, -15, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: SHSNOJ+MinionPro-It FontSubset: true FirstChar: 15 LastChar: 32 FontDescriptor: FontName: SHSNOJ+MinionPro-It Flags: Symbolic FontBBox: -61, -257, 767, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: SHSNOJ+MTMI FontSubset: true FirstChar: 31 LastChar: 32 FontDescriptor: FontName: SHSNOJ+MTMI Flags: Symbolic, AllCap FontBBox: 0, -207, 369, 672 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true TrueType: Font: BaseFont: MOTKIV+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: MOTKIV+TimesNewRomanPSMT Flags: Serif, Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Corbel2 FirstChar: 32 LastChar: 242 FontDescriptor: FontName: Corbel2 Flags: Nonsymbolic FontBBox: -553, -239, 1110, 952 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true CIDFontType2: Font: BaseFont: XDOLGZ+Corbel-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: XDOLGZ+Corbel-Bold Flags: Symbolic FontBBox: -556, -239, 1155, 952 FontFile2: true Font: BaseFont: SDFMOJ+Corbel CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: SDFMOJ+Corbel Flags: Symbolic FontBBox: -553, -239, 1110, 952 FontFile2: true XMP: 2020-11-12T12:11:31+05:30 Springer 2020-11-12T09:54:54+01:00 2020-11-12T09:54:54+01:00 application/pdf https://doi.org/10.1038/s41598-020-77013-1 Nature Publishing Group UK Scientific Reports, https://doi.org/10.1038/s41598-020-77013-1 Association of hyperuricemia and gamma glutamyl transferase as a marker of metabolic risk in alcohol use disorder Anna Hernández-Rubio Arantza Sanvisens Ferran Bolao Clara Pérez-Mañá Nuria García-Marchena Carla Fernández-Prendes Alvaro Muñoz Roberto Muga 10.1038/s41598-020-77013-1 2010-04-23 true springer.com springerlink.com https://doi.org/10.1038/s41598-020-77013-1 10.1038/s41598-020-77013-1 2045-2322 journal Scientific Reports The Author(s) 2010-04-23 true 10.1038/s41598-020-77013-1 noindex springer.com springerlink.com VoR uuid:06a2c4f9-7962-4cc2-a09c-9f9ee6681c98 uuid:db459f08-aeb3-4ca7-b1c8-1c900e9ba49b default 1 converted uuid:3e869880-2595-410b-8dae-c849fccb6ba3 converted to PDF/A-2b pdfToolbox 2020-11-12T12:12:43+05:30 Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) 2 B http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. issn Text internal Volume number volume Text internal Issue number number Text internal Starting page startingPage Text internal Ending page endingPage Text external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external Copyright copyright Text http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. DocumentID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 358, 313, 361, 301 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 271, 303, 273, 291 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 514, 293, 516, 281 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 269, 273, 272, 261 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 274, 273, 276, 261 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 259, 243, 262, 231 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 263, 243, 266, 231 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 283, 193, 286, 181 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 287, 193, 290, 181 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 481, 675, 556, 658 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 365, 724, 368, 712 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 369, 724, 372, 712 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 508, 714, 514, 702 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 515, 714, 521, 702 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 546, 704, 552, 692 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 475, 684, 481, 672 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 482, 684, 488, 672 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 190, 654, 196, 642 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 354, 634, 360, 622 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 361, 634, 367, 622 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 490, 614, 493, 602 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 494, 614, 500, 602 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 501, 614, 507, 602 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 510, 614, 516, 602 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 486, 584, 489, 572 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 293, 462, 299, 450 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 536, 272, 541, 260 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 543, 272, 548, 260 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 357, 156, 363, 144 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 546, 126, 552, 114 Flags: Print AppearanceDictionary: true Destination: 157 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 344, 502, 349, 490 Flags: Print AppearanceDictionary: true Destination: 108 Annotation: Subtype: Link Rect: 440, 462, 444, 450 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 193, 412, 198, 400 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 402, 392, 406, 380 Flags: Print AppearanceDictionary: true Destination: 137 Annotation: Subtype: Link Rect: 275, 170, 280, 158 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 282, 170, 287, 158 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 539, 140, 545, 128 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 548, 140, 554, 128 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 441, 130, 447, 118 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 450, 130, 455, 118 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 209, 110, 215, 98 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 216, 110, 222, 98 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 421, 110, 426, 98 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 428, 110, 433, 98 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 306, 80, 311, 68 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 313, 80, 318, 68 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 299, 60, 304, 48 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 305, 60, 311, 48 Flags: Print AppearanceDictionary: true Destination: 157 Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 421, 234, 426, 222 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 491, 224, 497, 212 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 498, 224, 504, 212 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 265, 194, 271, 182 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 404, 184, 410, 172 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 525, 134, 531, 122 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 431, 114, 437, 102 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 438, 114, 444, 102 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 393, 64, 399, 52 Flags: Print AppearanceDictionary: true Destination: 157 Thumb: true Page: Sequence: 5 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 401, 238, 404, 226 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 439, 228, 444, 216 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 255, 208, 260, 196 Flags: Print AppearanceDictionary: true Destination: 157 Annotation: Subtype: Link Rect: 262, 208, 267, 196 Flags: Print AppearanceDictionary: true Destination: 157 Thumb: true Page: Sequence: 7 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 351, 558, 443, 546 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 358, 448, 517, 436 Flags: Print AppearanceDictionary: true Thumb: true Checksum: c6edccfe Type: CRC32 Checksum: b083600ea5a1628823da4e171fe1ec43 Type: MD5 Checksum: 6f706b1d8b8f64ff7d92ec8ca37ba9452726a731 Type: SHA-1