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Villar Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Dec 21 10:55:05 2020 CET ModDate: Mon Dec 21 11:06:30 2020 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 5854943 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- TJRHPW+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 32 0 PUGCYQ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 45 0 DPCQAQ+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 47 0 AHVGJX+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 52 0 VLTFVE+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 27 0 OYGHCZ+MTSY Type 1C Custom yes yes yes 60 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 62 0 ACFPVT+MinionPro-Regular Type 1C Custom yes yes no 64 0 NDGZXT+MinionPro-It Type 1C Custom yes yes no 79 0 NQAVET+MinionPro-Bold Type 1C Custom yes yes no 93 0 MEXPTU+MTSYB Type 1C Custom yes yes no 102 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 04:17:08 CEST RepresentationInformation: pmc_33408681.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 11:43:41 CEST Size: 5854943 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 245 FreeObjects: 16 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab Destination: ariclecounter.1 Children: Item: Title: Introduction Destination: section*.2 Item: Title: Materials and Methods Destination: section*.3 Children: Item: Title: Inclusion Criteria Destination: section*.4 Item: Title: Data Collection Destination: section*.5 Item: Title: Statistical Analysis Destination: section*.6 Item: Title: Data Availability Destination: section*.7 Item: Title: Results Destination: section*.8 Children: Item: Title: Role of Lipid Specific Oligoclonal IgM Bands in Risk Stratification Destination: section*.9 Item: Title: Discussion Destination: section*.10 Item: Title: Data Availability Statement Destination: section*.11 Item: Title: Ethics Statement Destination: section*.12 Item: Title: Author Contributions Destination: section*.13 Item: Title: Funding Destination: section*.14 Item: Title: References Destination: section*.15 Info: Title: New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab Author: Luisa M. Villar Subject: Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis Keywords: multiple sclerosis, demyelinating diseases, biomarkers, natalizumab, progressive multifocal leucoencephalopathy, disease modifying treatments Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Dec 21 11:25:05 CET 2020 ModDate: Mon Dec 21 11:36:30 CET 2020 ID: 0xeee00ec9d3932818e80c4ec28a46510e, 0x58deb1976c76814f87fd2e2568744686 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 279 ImageHeight: 279 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 6759 ImageHeight: 9921 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 7087 ImageHeight: 6915 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: TJRHPW+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 150 FontDescriptor: FontName: TJRHPW+HelveticaNeueLTStd-Lt Flags: Serif, Symbolic FontBBox: -13, -214, 904, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ACFPVT+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: ACFPVT+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 1018, 811 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: AHVGJX+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 252 FontDescriptor: FontName: AHVGJX+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -133, -205, 891, 928 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MEXPTU+MTSYB FontSubset: true FirstChar: 67 LastChar: 68 FontDescriptor: FontName: MEXPTU+MTSYB Flags: Symbolic, AllCap FontBBox: 0, -83, 724, 583 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: VLTFVE+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 0 LastChar: 124 FontDescriptor: FontName: VLTFVE+HelveticaNeueLTStd-Bd Flags: Serif, Symbolic FontBBox: -9, -214, 925, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: OYGHCZ+MTSY FontSubset: true FirstChar: 6 LastChar: 68 FontDescriptor: FontName: OYGHCZ+MTSY Flags: Symbolic FontBBox: 0, -209, 944, 679 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: PUGCYQ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PUGCYQ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 751, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NQAVET+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: NQAVET+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 687, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: OBAZBH+RMTMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: OBAZBH+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 683, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DPCQAQ+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 252 FontDescriptor: FontName: DPCQAQ+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 907 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: NDGZXT+MinionPro-It FontSubset: true FirstChar: 3 LastChar: 252 FontDescriptor: FontName: NDGZXT+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 903, 810 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: 2020-12-21T15:25:05+05:30 LaTeX with hyperref package + hypdvips 2020-12-21T15:36:30+05:30 2020-12-21T15:36:30+05:30 application/pdf Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis Luisa M. 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