eec229ba4b763238503b04f3b3bfeec0 pmc_31959108.pdf d94672b4d295095c423c8774f5046a27261b2d76 pmc_31959108.pdf 2d14ffe3a8f082e75866e8b67e326095e7e0ad14d50235e836d3fc21c08d3978 pmc_31959108.pdf Title: Interaction of camel Lactoferrin derived peptides with DNA: a molecular dynamics study Subject: BMC Genomics, 2020, doi:10.1186/s12864-020-6458-7 Keywords: Antimicrobial peptide,DNA binding,Lactoferrin,Molecular dynamics simulation,CLFchimera Author: Zana Pirkhezranian Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Sat Jan 18 00:36:08 2020 CET ModDate: Mon Jan 20 14:26:23 2020 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 3498477 bytes Optimized: no PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- HNDKNO+JtftkfAdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 16 0 HNEDPH+CgmnphAdvTTe45e47d2 Type 1C WinAnsi yes yes no 17 0 HNEDPI+GhqbmcAdvTTb5929f4c Type 1C WinAnsi yes yes no 18 0 HNEEDI+LpsbtlAdvTT99c4c969 Type 1C WinAnsi yes yes no 20 0 HNEEEI+BbrwqjAdvTT86d47313 Type 1C WinAnsi yes yes no 21 0 HNEEEJ+JxdlbmAdvTT86d47313+20 Type 1C WinAnsi yes yes no 22 0 MyriadPro-Regular Type 1C Custom yes no yes 19 0 HNEGAP+SskdndAdvTT7329fd89.I Type 1C WinAnsi yes yes no 24 0 HNEGEA+MmlshgAdvTT8861b38f.I Type 1C WinAnsi yes yes no 23 0 HNGEFI+DwgxvvAdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 344 0 HNGEII+TsdygjAdvTT8861b38f.I+20 Type 1C WinAnsi yes yes no 122 0 HNGEJJ+TtwddsAdvTT86d47313+22 Type 1C Custom yes yes no 127 0 HNGEJK+SvytwcAdvTTb5929f4c+22 Type 1C Custom yes yes no 162 0 HNGPFJ+WwljhfAdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 207 0 HNJFBC+QtlqqvAdvTT86d47313+03 Type 1C Custom yes yes yes 208 0 HNJFBD+RwqhqpAdvTT99c4c969+20 Type 1C WinAnsi yes yes no 209 0 HNJFHC+DljwylAdvTTaf7f9f4f.B+20 Type 1C WinAnsi yes yes no 312 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-18 07:06:19 CET RepresentationInformation: pmc_31959108.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-08-03 03:36:58 CEST Size: 3498477 Format: PDF Version: 1.3 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR2' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR4' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR6' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR6' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR7' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR9' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR12' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR19' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR20' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR27' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR29' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR28' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR31' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR32' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR7' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR8' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig1' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig2' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig2' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig3' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig3' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR34' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR35' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR36' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR37' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR38' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR39' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig4' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig5' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM10' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR40' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR41' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR40' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR42' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM11' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM10' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM12' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM13' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM14' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR43' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR44' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM15' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_MOESM16' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR45' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig10' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig11' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig12' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig12' cannot be found Offset: 3487083 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Fig13' cannot be found Offset: 3487083 MIMEtype: application/pdf PDFMetadata: Objects: 546 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Molecular structure models Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Molecular dynamics simulations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Binding free energy estimates Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Results and discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Children: Item: Title: Molecular dynamics simulation in aqueous solution of the isolated peptides and BDNA Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Structural fluctuation analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Molecular dynamics simulation of the peptide-DNA systems Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Center of mass distances Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Number of hydrogen bonds and salt bridges Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Contacting surface area Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: MM/PBSA binding free energy estimate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Effect of CLFchimera concentration on DNA binding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Number of hydrogen bonds and salt bridges Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Contacting surface area Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: MM/PBSA binding free energy estimate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Structural characterization of CLFchimera Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Effect of CLFchimera concentration on DNA conformation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Supplementary information Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Abbreviations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Authors’ contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Availability of data and materials Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Ethics approval and consent to participate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Consent for publication Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Author details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Publisher’s Note Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Info: Title: Interaction of camel Lactoferrin derived peptides with DNA: a molecular dynamics study Author: Zana Pirkhezranian Subject: BMC Genomics, 2020, doi:10.1186/s12864-020-6458-7 Keywords: Antimicrobial peptide,DNA binding,Lactoferrin,Molecular dynamics simulation,CLFchimera Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Sat Jan 18 00:36:08 CET 2020 ModDate: Mon Jan 20 14:26:23 CET 2020 ID: 0x5bc90297f7d951ac62abf0322d6bf8d8, 0xcd42cf11f6b9b7ec2af654f72ea263b6 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 176 ImageHeight: 182 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 688 ImageHeight: 126 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 33 ImageHeight: 63 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1183 ImageHeight: 948 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 1549 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 1231 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1183 ImageHeight: 534 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 684 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1947 ImageHeight: 838 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 897 ImageHeight: 693 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1183 ImageHeight: 1090 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1949 ImageHeight: 769 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1183 ImageHeight: 854 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1949 ImageHeight: 1433 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1183 ImageHeight: 933 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 897 ImageHeight: 587 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: HNGEJK+SvytwcAdvTTb5929f4c+22 FontSubset: true FirstChar: 21 LastChar: 22 FontDescriptor: FontName: HNGEJK+SvytwcAdvTTb5929f4c+22 Flags: Nonsymbolic FontBBox: -10, -218, 1083, 812 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HNGPFJ+WwljhfAdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 151 FontDescriptor: FontName: HNGPFJ+WwljhfAdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -447, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNDKNO+JtftkfAdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: HNDKNO+JtftkfAdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNJFBC+QtlqqvAdvTT86d47313+03 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: HNJFBC+QtlqqvAdvTT86d47313+03 Flags: Symbolic FontBBox: -281, -250, 906, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: HNEDPH+CgmnphAdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: HNEDPH+CgmnphAdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNJFBD+RwqhqpAdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: HNJFBD+RwqhqpAdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -447, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNEDPI+GhqbmcAdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 243 FontDescriptor: FontName: HNEDPI+GhqbmcAdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HNEEDI+LpsbtlAdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: HNEEDI+LpsbtlAdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNEEEI+BbrwqjAdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 233 FontDescriptor: FontName: HNEEEI+BbrwqjAdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNEEEJ+JxdlbmAdvTT86d47313+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: HNEEEJ+JxdlbmAdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -218, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNEGEA+MmlshgAdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: HNEGEA+MmlshgAdvTT8861b38f.I Flags: Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNEGAP+SskdndAdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: HNEGAP+SskdndAdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNGEFI+DwgxvvAdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: HNGEFI+DwgxvvAdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNJFHC+DljwylAdvTTaf7f9f4f.B+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: HNJFHC+DljwylAdvTTaf7f9f4f.B+20 Flags: Nonsymbolic FontBBox: -468, -197, 1656, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNGEII+TsdygjAdvTT8861b38f.I+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: HNGEII+TsdygjAdvTT8861b38f.I+20 Flags: Nonsymbolic FontBBox: -218, -218, 1385, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HNGEJJ+TtwddsAdvTT86d47313+22 FontSubset: true FirstChar: 21 LastChar: 22 FontDescriptor: FontName: HNGEJJ+TtwddsAdvTT86d47313+22 Flags: Nonsymbolic FontBBox: -166, -250, 1031, 864 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: Antimicrobial peptide,DNA binding,Lactoferrin,Molecular dynamics simulation,CLFchimera Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) application/pdf 10.1186/s12864-020-6458-7 BMC Genomics BMC Genomics, 2020, doi:10.1186/s12864-020-6458-7 Antimicrobial peptide DNA binding Lactoferrin Molecular dynamics simulation CLFchimera Interaction of camel Lactoferrin derived peptides with DNA: a molecular dynamics study Zana Pirkhezranian Mojtaba Tahmoorespur Xavier Daura Hassan Monhemi Mohammad Hadi Sekhavati 2020-01-20T14:26:23+01:00 2020-01-20T14:26:23+01:00 2020-01-18T07:36:08+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode uuid:c62750f6-b068-4978-a7e9-948ee2072188 uuid:c7329f7e-e426-4f4b-8305-48eafb448e93 default 1 converted uuid:c62750f6-b068-4978-a7e9-948ee2072188 converted to PDF/A-2b pdfToolbox 2020-01-18T07:44:07+08:00 2 B Mohammad Hadi Sekhavati http://orcid.org/0000-0001-8091-3798 Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. editorInfo Bag EditorInformation external Editor information: contains the name of each editor and his/her ORCID identifier. seriesEditorInfo Bag SeriesEditorInformation external Series editor information: contains the name of each series editor and his/her ORCID identifier. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. EditorInformation http://springernature.com/ns/xmpExtensions/2.0/editorInfo/ editor Specifies the types of editor information: name and ORCID of an editor. name Text Gives the name of an editor. orcid URI Gives the ORCID of an editor. SeriesEditorInformation http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/ seriesEditor Specifies the types of series editor information: name and ORCID of a series editor. name Text Gives the name of a series editor. orcid URI Gives the ORCID of a series editor. http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://ns.adobe.com/pdfx/1.3/ pdfx PDF/X ID Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 496, 635, 538, 677 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 528, 573, 537, 582 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 194, 186, 199, 196 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 104, 162, 109, 172 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 280, 150, 285, 160 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 517, 258, 522, 268 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 528, 258, 533, 268 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 488, 210, 493, 220 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 499, 210, 504, 220 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 380, 174, 385, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 390, 174, 395, 184 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 460, 90, 464, 100 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 470, 90, 475, 100 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 239, 65, 357, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 182, 41, 321, 48 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 114, 117, 176, 125 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 179, 117, 235, 125 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 80, 645, 90, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 231, 609, 241, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 275, 585, 285, 594 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 100, 573, 110, 582 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 169, 573, 179, 582 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 257, 573, 266, 582 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 87, 561, 97, 570 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 259, 525, 269, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 275, 525, 285, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 197, 441, 207, 450 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 82, 369, 92, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 275, 345, 285, 354 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 136, 273, 146, 282 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 503, 513, 508, 522 Flags: Print AppearanceDictionary: true Destination: 11 Annotation: Subtype: Link Rect: 367, 381, 377, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 481, 381, 538, 390 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 369, 495, 378 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 525, 369, 535, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 436, 345, 538, 354 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 333, 378, 342 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 388, 333, 398, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 509, 273, 519, 282 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 525, 273, 535, 282 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 436, 261, 446, 270 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 172, 693, 181, 702 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 489, 69, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 75, 489, 85, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 186, 429, 196, 438 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 176, 357, 181, 366 Flags: Print AppearanceDictionary: true Destination: 11 Annotation: Subtype: Link Rect: 477, 489, 538, 498 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 477, 423, 486 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 433, 477, 443, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 329, 453, 339, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 414, 381, 424, 390 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 59, 681, 232, 690 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 126, 621, 136, 630 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 141, 621, 151, 630 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 231, 585, 241, 594 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 415, 681, 420, 690 Flags: Print AppearanceDictionary: true Destination: 11 Annotation: Subtype: Link Rect: 510, 525, 515, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 349, 489, 354, 498 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 483, 489, 488, 498 Flags: Print AppearanceDictionary: true Destination: 94 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 250, 657, 255, 666 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 261, 657, 266, 666 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 74, 645, 79, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 184, 609, 189, 618 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 481, 669, 485, 678 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 364, 645, 369, 654 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 370, 573, 375, 582 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 512, 573, 516, 582 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 370, 549, 375, 558 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 511, 549, 516, 558 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 325, 465, 330, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 398, 465, 403, 474 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 531, 465, 536, 474 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 466, 405, 470, 414 Flags: Print AppearanceDictionary: true Destination: 94 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 189, 489, 194, 498 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 138, 417, 147, 426 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 153, 417, 163, 426 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 130, 393, 140, 402 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 145, 393, 155, 402 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 283, 321, 288, 330 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 143, 249, 153, 258 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 59, 213, 69, 222 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 142, 189, 147, 198 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 137, 177, 141, 186 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 531, 513, 536, 522 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 493, 417, 498, 426 Flags: Print AppearanceDictionary: true Destination: 201 Annotation: Subtype: Link Rect: 398, 273, 403, 282 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 488, 273, 493, 282 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 369, 141, 374, 150 Flags: Print AppearanceDictionary: true Destination: 161 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 100, 417, 110, 426 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 250, 357, 260, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 266, 357, 276, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 280, 345, 285, 354 Flags: Print AppearanceDictionary: true Destination: 161 Annotation: Subtype: Link Rect: 96, 297, 106, 306 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 402, 453, 412, 462 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 487, 417, 492, 426 Flags: Print AppearanceDictionary: true Destination: 161 Annotation: Subtype: Link Rect: 435, 357, 445, 366 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 389, 345, 394, 354 Flags: Print AppearanceDictionary: true Destination: 161 Annotation: Subtype: Link Rect: 320, 321, 330, 330 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 220, 249, 225, 258 Flags: Print AppearanceDictionary: true Destination: 7 Annotation: Subtype: Link Rect: 230, 237, 240, 246 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 137, 225, 146, 234 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 256, 177, 261, 186 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 242, 141, 247, 150 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 526, 381, 536, 390 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 479, 285, 488, 294 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 94, 525, 104, 534 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 198, 477, 208, 486 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 143, 405, 153, 414 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 171, 345, 176, 354 Flags: Print AppearanceDictionary: true Destination: 7 Annotation: Subtype: Link Rect: 195, 333, 205, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 102, 285, 107, 294 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 401, 501, 406, 510 Flags: Print AppearanceDictionary: true Destination: 53 Annotation: Subtype: Link Rect: 344, 321, 349, 330 Flags: Print AppearanceDictionary: true Destination: 53 Annotation: Subtype: Link Rect: 507, 321, 516, 330 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 10 Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 96, 393, 100, 402 Flags: Print AppearanceDictionary: true Destination: 201 Annotation: Subtype: Link Rect: 125, 393, 130, 402 Flags: Print AppearanceDictionary: true Destination: 53 Annotation: Subtype: Link Rect: 94, 345, 104, 354 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 169, 297, 179, 306 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 275, 261, 285, 270 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 253, 105, 263, 114 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 373, 345, 383, 354 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 388, 333, 397, 342 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 439, 321, 449, 330 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 230, 232, 284, 239 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 56, 223, 129, 230 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 13 Thumb: true Page: Sequence: 14 Thumb: true Checksum: 4d2534e8 Type: CRC32 Checksum: eec229ba4b763238503b04f3b3bfeec0 Type: MD5 Checksum: d94672b4d295095c423c8774f5046a27261b2d76 Type: SHA-1