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     Item: 
      Title: Comparing the effectiveness and cost-­effectiveness of self-­management interventions in four high-­priority chronic conditions in Europe (COMPAR-­EU): a research protocol
      Children: 
       Item: 
        Title: ABSTRACT
       Item: 
        Title: Introduction
        Children: 
         Item: 
          Title: Aim
       Item: 
        Title: Methods and analysis
        Children: 
         Item: 
          Title: Phase 1: refinement and validation of a taxonomy of SMIs
         Item: 
          Title: Phase 2: development of core outcome sets for each condition
          Children: 
           Item: 
            Title: Outcome catalogue
           Item: 
            Title: Systematic review of how patients value self-management outcomes
           Item: 
            Title: Delphi survey with patient representatives
           Item: 
            Title: Consensus workshop
         Item: 
          Title: Phase 3: systematic review—descriptive synthesis of the evidence
          Children: 
           Item: 
            Title: Preparations for data collection
           Item: 
            Title: Literature search and screening
           Item: 
            Title: Data extraction and collection
           Item: 
            Title: Descriptive analysis and summary of SMIs and outcomes
         Item: 
          Title: Phase 4: systematic review—NMA and certainty of evidence
          Children: 
           Item: 
            Title: Network meta-analysis
           Item: 
            Title: Evaluation and summary of the certainty of the evidence
         Item: 
          Title: Phase 5: model the cost-effectiveness of effective SMIs
         Item: 
          Title: Phase 6: analyse the contextual factors that promote implementation in real life contexts
         Item: 
          Title: Phase 7: development and piloting of the COMPAR-EU information technology platform, and preparation for future implementation
          Children: 
           Item: 
            Title: Development of COMPAR-EU online platform
           Item: 
            Title: Piloting and refinement of decision-making tools with different stakeholders
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            Title: Preparation of future implementation
       Item: 
        Title: Patient and public involvement
       Item: 
        Title: Ethics and dissemination
       Item: 
        Title: Data sharing statement
       Item: 
        Title: Patient and public involvement
       Item: 
        Title: References
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