18d18531d6c8e6b2e18b6654653ed677 pmc_32143308.pdf 2e571f91c21dd7cacd904ee33fe5e8f0a7cc05ab pmc_32143308.pdf b300aff15e1e866f0c5b1859a2d5278e6dbde00e0053e455ea1e92f15d333e0f pmc_32143308.pdf Title: Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of Other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study Subject: Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the association between polyphenol intake and the components of MetS. This cross-sectional analysis involved 6633 men and women included in the PREDIMED (PREvención con DIeta MEDiterranea-Plus) study. The polyphenol content of foods was estimated from the Phenol-Explorer 3.6 database. The mean of total polyphenol intake was 846 318 mg/day. Except for stilbenes, women had higher polyphenol intake than men. Total polyphenol intake was higher in older participants (>70 years of age) compared to their younger counterparts. Participants with body mass index (BMI) >35 kg/m2 reported lower total polyphenol, flavonoid, and stilbene intake than those with lower BMI. Total polyphenol intake was not associated with a better profile concerning MetS components, except for high-density lipoprotein cholesterol (HDL-c), although stilbenes, lignans, and other polyphenols showed an inverse association with blood pressure, fasting plasma glucose, and triglycerides. A direct association with HDL-c was found for all subclasses except lignans and phenolic acids. To conclude, in participants with MetS, higher intake of several polyphenol subclasses was associated with a better profile of MetS components, especially HDL-c. Keywords: polyphenols; metabolic syndrome; Mediterranean diet; glignans; stilbenes; HDL-cholesterol Author: Sara Castro-Barquero, Anna Tresserra-Rimbau, Facundo Vitelli-Storelli, Mónica Doménech, Jordi Salas-Salvadó, Vicente Martín-Sánchez, María Rubín-García, Pilar Buil-Cosiales, Dolores Corella, Montserrat Fitó, Dora Romaguera, Jesús Vioque, Ángel María Alonso-Gómez, Julia Wärnberg, José Alfredo Martínez, Luís Serra-Majem, Francisco José Tinahones, José Lapetra, Xavier Pintó, Josep Antonio Tur, Antonio Garcia-Rios, Laura García-Molina, Miguel Delgado-Rodriguez, Pilar Matía-Martín, Lidia Daimiel, Josep Vidal, Clotilde Vázquez, Montserrat Cofán, Andrea Romanos-Nanclares, Nerea Becerra-Tomas, Rocio Barragan, Olga Castañer, Jadwiga Konieczna, Sandra González-Palacios, Carolina Sorto-Sánchez, Jessica Pérez-López, María Angeles Zulet, Inmaculada Bautista-Castaño, Rosa Casas, Ana María Gómez-Perez, José Manuel Santos-Lozano, María Ángeles Rodríguez-Sanchez, Alicia Julibert, Nerea Martín-Calvo, Pablo Hernández-Alonso, José V Sorlí, Albert Sanllorente, Aina María Galmés-Panadés, Eugenio Cases-Pérez, Leire Goicolea-Güemez, Miguel Ruiz-Canela, Nancy Babio, Álvaro Hernáez, Rosa María Lamuela-Raventós and Ramon Estruch Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.18 CreationDate: Wed Mar 4 11:44:22 2020 CET ModDate: Wed Mar 4 11:44:22 2020 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1021316 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- OOJKRC+URWPalladioL-Ital Type 1 Custom yes yes no 92 0 VOGIDC+URWPalladioL-Bold Type 1 Custom yes yes no 93 0 QTLELQ+Pxbsy Type 1 Builtin yes yes no 94 0 WIRPUU+VnURWPalladioL-Bold Type 1 Custom yes yes no 95 0 UOBFYN+URWPalladioL-Roma Type 1 Custom yes yes no 96 0 SDIDBK+VnURWPalladioL 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きちぴづひどちぬびぜ〴ぜ〰ちのつぜ〴ぜ〰きづぴとはつびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮ㄩ‾㸊⡜㌷㙜㌷㝜〰いづびどでのぜ〴ぜ〰はてぜ〴ぜ〰ぴとづぜ〴ぜ〰こぴふつべぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㈩‾㸊⡜㌷㙜㌷㝜〰ぐちひぴどっどばちのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㌩‾㸊⡜㌷㙜㌷㝜〰ぅびぴどねちぴどはのぜ〴ぜ〰はてぜ〴ぜ〰いどづぴちひべぜ〴ぜ〰ぐはぬべばとづのはぬぜ〴ぜ〰ぉのぴちにづぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰ちのつぜ〴ぜ〰くふぴっはねづぜ〴ぜ〰ぁびびづびびねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰ぁのちぬべびどびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Children: Item: Title: いづびどでのぜ〴ぜ〰はてぜ〴ぜ〰ぴとづぜ〴ぜ〰こぴふつべぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㈩‾㸊⡜㌷㙜㌷㝜〰ぐちひぴどっどばちのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㌩‾㸊⡜㌷㙜㌷㝜〰ぅびぴどねちぴどはのぜ〴ぜ〰はてぜ〴ぜ〰いどづぴちひべぜ〴ぜ〰ぐはぬべばとづのはぬぜ〴ぜ〰ぉのぴちにづぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰ちのつぜ〴ぜ〰くふぴっはねづぜ〴ぜ〰ぁびびづびびねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰ぁのちぬべびどびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: ぐちひぴどっどばちのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㌩‾㸊⡜㌷㙜㌷㝜〰ぅびぴどねちぴどはのぜ〴ぜ〰はてぜ〴ぜ〰いどづぴちひべぜ〴ぜ〰ぐはぬべばとづのはぬぜ〴ぜ〰ぉのぴちにづぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰ちのつぜ〴ぜ〰くふぴっはねづぜ〴ぜ〰ぁびびづびびねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰ぁのちぬべびどびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: ぅびぴどねちぴどはのぜ〴ぜ〰はてぜ〴ぜ〰いどづぴちひべぜ〴ぜ〰ぐはぬべばとづのはぬぜ〴ぜ〰ぉのぴちにづぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰ちのつぜ〴ぜ〰くふぴっはねづぜ〴ぜ〰ぁびびづびびねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰ぁのちぬべびどびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: きづちびふひづねづのぴびぜ〴ぜ〰ちのつぜ〴ぜ〰くふぴっはねづぜ〴ぜ〰ぁびびづびびねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰こぴちぴどびぴどっちぬぜ〴ぜ〰ぁのちぬべびどびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: こぴちぴどびぴどっちぬぜ〴ぜ〰ぁのちぬべびどびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: げづびふぬぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸴ Item: Title: いどびっふびびどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸵ Item: Title: ぃはのっぬふびどはのびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸵ Item: Title: げづてづひづのっづび Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: UOBFYN+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 246 FontDescriptor: FontName: UOBFYN+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: SDIDBK+VnURWPalladioL FontSubset: true FirstChar: 129 LastChar: 243 FontDescriptor: FontName: SDIDBK+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true 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