c61dd5de9e041247f5ec822dbc42ffe7 pmc_32295053.pdf 0fb238732db83f41b1044eccbd8a7281a95c665e pmc_32295053.pdf 09a14a6df08cf3b9701bbcbb0ae6412276676b516e6aadc15646f3ffa6936d86 pmc_32295053.pdf Producer: iText® 7.1.1 ©2000-2018 iText Group NV (AGPL-version) CreationDate: Thu Apr 23 13:04:46 2020 CEST ModDate: Thu Apr 23 13:04:46 2020 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2507772 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MWHIBA+VnURWPalladioL Type 1 Custom yes yes no 10 0 QXGEVS+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 BZWIWR+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 LZDGTK+Rpxb Type 1 Builtin yes yes no 24 0 DAIZZJ+URWPalladioL-Roma Type 1 Custom yes yes no 28 0 FATHTC+Rpxr Type 1 Builtin yes yes no 32 0 IYAOHD+PazoMath Type 1 Builtin yes yes no 36 0 DIMMOC+VnURWPalladioL-Bold Type 1 Custom yes yes no 40 0 NPLVPL+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 48 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 70 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 74 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 78 0 YICMPF+Rpcxr Type 1 Builtin yes yes no 88 0 HHMDGK+Pxsy Type 1 Builtin yes yes no 92 0 HCGJAI+EURM10 Type 1 Builtin yes yes no 96 0 BCDEEE+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 114 0 BCDFEE+PalatinoLinotype-Italic TrueType WinAnsi yes yes no 118 0 BCDGEE+PalatinoLinotype-Bold TrueType WinAnsi yes yes no 122 0 BCDHEE+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 126 0 ArialMT TrueType WinAnsi no no no 137 0 Arial-BoldMT TrueType WinAnsi no no no 140 0 BCDEEE+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 147 0 BCDFEE+PalatinoLinotype-Italic TrueType WinAnsi yes yes no 151 0 BCDGEE+PalatinoLinotype-Bold TrueType WinAnsi yes yes no 155 0 BCDHEE+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 159 0 ArialMT TrueType WinAnsi no no no 170 0 Arial-BoldMT TrueType WinAnsi no no no 173 0 BCDEEE+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 184 0 BCDFEE+PalatinoLinotype-Italic TrueType WinAnsi yes yes no 188 0 BCDGEE+PalatinoLinotype-Bold TrueType WinAnsi yes yes no 192 0 BCDHEE+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 196 0 SymbolMT CID TrueType Identity-H yes no yes 203 0 MKAJEF+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 218 0 MKAJFH+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 221 0 MKAJFI+PalatinoLinotype CID TrueType Identity-H yes yes yes 224 0 MKAJFJ+PalatinoLinotype TrueType WinAnsi yes yes no 230 0 MKAJEF+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 240 0 MKAJFH+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 243 0 MKAJFI+PalatinoLinotype CID TrueType Identity-H yes yes yes 246 0 MKAJFJ+PalatinoLinotype TrueType WinAnsi yes yes no 252 0 MKAJEF+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 262 0 MKAJFH+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 265 0 MKAJFI+PalatinoLinotype CID TrueType Identity-H yes yes yes 268 0 MKAJFJ+PalatinoLinotype TrueType WinAnsi yes yes no 274 0 MKAJEF+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 285 0 MKAJFH+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 288 0 MKAJFI+PalatinoLinotype CID TrueType Identity-H yes yes yes 291 0 MKAJFJ+PalatinoLinotype TrueType WinAnsi yes yes no 297 0 MKAKAF+TimesNewRoman CID TrueType Identity-H yes yes yes 300 0 GBLQZB+Rpxi Type 1 Builtin yes yes no 320 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-18 06:45:52 CET RepresentationInformation: pmc_32295053.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-07-13 03:38:26 CEST Size: 2507772 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 519 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Children: Item: Title: Synthesis and Characterization of NPs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Children: Item: Title: Preparation of 3 Iodopropyl-Functionalized AuCeO2 (I AuCeO2) Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Preparation of Triphenylphosphonium-Functionalized AuCeO2 (TPP AuCeO2) Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Cell Culture Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Children: Item: Title: Cellular Viability and Proliferation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Cellular Uptake and Internalization of Conjugate by Confocal Microscopy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: Measurement of the Mitochondrial O2 Consumption Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Item: Title: Measurement of Mitochondrial Membrane Potential (m) and Total ROS Production Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@a38d7a3 Item: Title: ATP Determination Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77f99a05 Item: Title: Real-Time PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@63440df3 Item: Title: Western Blot Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3aeaafa6 Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@76a3e297 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Children: Item: Title: Synthesis and Characterization of Nanoparticles Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: Cell Culture Studies Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Cellular Viability and Proliferation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Cellular Uptake and Internalization of Conjugate by Confocal Microscopy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Mitochondrial Functional Studies after Nanoparticles Treatments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Info: Producer: iText® 7.1.1 ©2000-2018 iText Group NV (AGPL-version) CreationDate: Thu Apr 23 13:04:46 CEST 2020 ModDate: Thu Apr 23 13:04:46 CEST 2020 ID: 0xa787d01f19aaeec598fcd3b3c99d507f, 0xa787d01f19aaeec598fcd3b3c99d507f Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: FATHTC+Rpxr FontSubset: true FirstChar: 11 LastChar: 61 FontDescriptor: FontName: FATHTC+Rpxr Flags: Symbolic FontBBox: -40, -283, 904, 728 FontFile: true Font: BaseFont: HCGJAI+EURM10 FontSubset: true FirstChar: 11 LastChar: 33 FontDescriptor: FontName: HCGJAI+EURM10 Flags: Symbolic FontBBox: -32, -243, 1060, 720 FontFile: true Font: BaseFont: GBLQZB+Rpxi FontSubset: true FirstChar: 11 LastChar: 11 FontDescriptor: FontName: GBLQZB+Rpxi Flags: Symbolic FontBBox: -162, -280, 856, 733 FontFile: true Font: BaseFont: IYAOHD+PazoMath FontSubset: true FirstChar: 68 LastChar: 89 FontDescriptor: FontName: IYAOHD+PazoMath Flags: Symbolic FontBBox: -40, -283, 878, 946 FontFile: true Font: BaseFont: BZWIWR+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 122 FontDescriptor: FontName: BZWIWR+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: LZDGTK+Rpxb FontSubset: true FirstChar: 11 LastChar: 11 FontDescriptor: FontName: LZDGTK+Rpxb Flags: Symbolic FontBBox: -57, -266, 932, 729 FontFile: true Font: BaseFont: DIMMOC+VnURWPalladioL-Bold FontSubset: true FirstChar: 178 LastChar: 243 FontDescriptor: FontName: DIMMOC+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: YICMPF+Rpcxr FontSubset: true FirstChar: 151 LastChar: 174 FontDescriptor: FontName: YICMPF+Rpcxr Flags: Symbolic FontBBox: -212, -286, 1344, 973 FontFile: true Font: BaseFont: MWHIBA+VnURWPalladioL FontSubset: true FirstChar: 161 LastChar: 226 FontDescriptor: FontName: MWHIBA+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: DAIZZJ+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: DAIZZJ+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: HHMDGK+Pxsy FontSubset: true FirstChar: 0 LastChar: 14 FontDescriptor: FontName: HHMDGK+Pxsy Flags: Symbolic FontBBox: -21, -994, 1292, 912 FontFile: true Font: BaseFont: QXGEVS+URWPalladioL-Ital FontSubset: true FirstChar: 40 LastChar: 122 FontDescriptor: FontName: QXGEVS+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 75, 757, 212, 793 Annotation: Subtype: Link Rect: 474, 757, 519, 793 Annotation: Subtype: Link Rect: 209, 621, 220, 634 Annotation: Subtype: Link Rect: 368, 621, 379, 634 Annotation: Subtype: Link Rect: 277, 607, 288, 621 Annotation: Subtype: Link Rect: 400, 607, 411, 621 Annotation: Subtype: Link Rect: 187, 594, 198, 607 Annotation: Subtype: Link Rect: 315, 594, 326, 607 Annotation: Subtype: Link Rect: 186, 38, 265, 50 Annotation: Subtype: Link Rect: 380, 38, 519, 50 Annotation: Subtype: Link Rect: 466, 335, 518, 354 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 118, 618, 125, 627 ActionDest: 314 Annotation: Subtype: Link Rect: 128, 618, 135, 627 ActionDest: 314 Annotation: Subtype: Link Rect: 143, 591, 150, 600 ActionDest: 314 Annotation: Subtype: Link Rect: 150, 591, 157, 600 ActionDest: 314 Annotation: Subtype: Link Rect: 269, 591, 276, 600 ActionDest: 314 Annotation: Subtype: Link Rect: 269, 564, 276, 573 ActionDest: 314 Annotation: Subtype: Link Rect: 360, 550, 372, 560 ActionDest: 314 Annotation: Subtype: Link Rect: 372, 551, 384, 560 ActionDest: 314 Annotation: Subtype: Link Rect: 488, 537, 500, 546 ActionDest: 314 Annotation: Subtype: Link Rect: 503, 537, 515, 546 ActionDest: 314 Annotation: Subtype: Link Rect: 247, 510, 259, 519 ActionDest: 314 Annotation: Subtype: Link Rect: 259, 510, 271, 519 ActionDest: 314 Annotation: Subtype: Link Rect: 274, 510, 286, 519 ActionDest: 314 Annotation: Subtype: Link Rect: 268, 483, 280, 492 ActionDest: 317 Annotation: Subtype: Link Rect: 283, 483, 295, 492 ActionDest: 317 Annotation: Subtype: Link Rect: 424, 469, 431, 479 ActionDest: 314 Annotation: Subtype: Link Rect: 236, 402, 248, 411 ActionDest: 317 Annotation: Subtype: Link Rect: 249, 402, 261, 411 ActionDest: 317 Annotation: Subtype: Link Rect: 117, 388, 129, 397 ActionDest: 317 Annotation: Subtype: Link Rect: 476, 375, 488, 384 ActionDest: 317 Annotation: Subtype: Link Rect: 488, 375, 500, 384 ActionDest: 317 Annotation: Subtype: Link Rect: 503, 375, 515, 384 ActionDest: 317 Annotation: Subtype: Link Rect: 424, 321, 436, 330 ActionDest: 317 Annotation: Subtype: Link Rect: 303, 280, 315, 289 ActionDest: 317 Annotation: Subtype: Link Rect: 479, 226, 490, 235 ActionDest: 314 Annotation: Subtype: Link Rect: 491, 226, 503, 235 ActionDest: 317 Annotation: Subtype: Link Rect: 503, 226, 515, 235 ActionDest: 317 Annotation: Subtype: Link Rect: 185, 186, 197, 195 ActionDest: 317 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 108, 663, 120, 672 ActionDest: 314 Annotation: Subtype: Link Rect: 120, 663, 132, 672 ActionDest: 317 Annotation: Subtype: Link Rect: 100, 116, 112, 125 ActionDest: 317 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 491, 655, 503, 665 ActionDest: 317 Annotation: Subtype: Link Rect: 503, 655, 515, 665 ActionDest: 317 Annotation: Subtype: Link Rect: 225, 561, 237, 570 ActionDest: 317 Annotation: Subtype: Link Rect: 237, 561, 249, 570 ActionDest: 317 Annotation: Subtype: Link Rect: 112, 547, 124, 557 ActionDest: 324 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 202, 478, 214, 487 ActionDest: 324 Annotation: Subtype: Link Rect: 126, 191, 133, 204 ActionDest: 106 Annotation: Subtype: Link Rect: 151, 180, 163, 189 ActionDest: 314 Annotation: Subtype: Link Rect: 450, 150, 457, 164 ActionDest: 106 Annotation: Subtype: Link Rect: 488, 110, 495, 121 ActionDest: 176 Page: Sequence: 6 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 115, 349, 126, 358 ActionDest: 314 Annotation: Subtype: Link Rect: 178, 292, 185, 304 ActionDest: 106 Annotation: Subtype: Link Rect: 150, 238, 157, 250 ActionDest: 106 Annotation: Subtype: Link Rect: 369, 224, 376, 236 ActionDest: 176 Annotation: Subtype: Link Rect: 264, 197, 271, 209 ActionDest: 106 Annotation: Subtype: Link Rect: 206, 143, 213, 157 ActionDest: 106 Annotation: Subtype: Link Rect: 256, 76, 263, 88 ActionDest: 106 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 300, 726, 307, 740 ActionDest: 106 Annotation: Subtype: Link Rect: 414, 726, 421, 740 ActionDest: 212 Annotation: Subtype: Link Rect: 231, 675, 243, 684 ActionDest: 324 Annotation: Subtype: Link Rect: 380, 591, 387, 603 ActionDest: 176 Annotation: Subtype: Link Rect: 126, 236, 138, 245 ActionDest: 314 Annotation: Subtype: Link Rect: 500, 110, 507, 122 ActionDest: 234 Annotation: Subtype: Link Rect: 162, 69, 169, 81 ActionDest: 234 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 425, 740, 431, 752 ActionDest: 234 Annotation: Subtype: Link Rect: 429, 729, 441, 738 ActionDest: 317 Annotation: Subtype: Link Rect: 442, 729, 453, 738 ActionDest: 324 Annotation: Subtype: Link Rect: 265, 325, 272, 337 ActionDest: 256 Annotation: Subtype: Link Rect: 451, 244, 458, 256 ActionDest: 256 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 251, 295, 258, 306 ActionDest: 256 Annotation: Subtype: Link Rect: 349, 254, 356, 266 ActionDest: 256 Annotation: Subtype: Link Rect: 110, 200, 117, 212 ActionDest: 279 Annotation: Subtype: Link Rect: 179, 119, 186, 131 ActionDest: 279 Annotation: Subtype: Link Rect: 442, 92, 449, 104 ActionDest: 279 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 143, 161, 155, 170 ActionDest: 314 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 384, 661, 396, 671 ActionDest: 314 Annotation: Subtype: Link Rect: 112, 526, 124, 535 ActionDest: 324 Annotation: Subtype: Link Rect: 127, 526, 139, 535 ActionDest: 324 Annotation: Subtype: Link Rect: 229, 148, 241, 157 ActionDest: 324 Annotation: Subtype: Link Rect: 242, 148, 254, 157 ActionDest: 324 Annotation: Subtype: Link Rect: 254, 148, 266, 157 ActionDest: 324 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 346, 742, 358, 752 ActionDest: 324 Annotation: Subtype: Link Rect: 359, 742, 371, 752 ActionDest: 324 Annotation: Subtype: Link Rect: 315, 497, 322, 508 ActionDest: 256 Annotation: Subtype: Link Rect: 337, 337, 518, 348 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 288, 708, 326, 719 Annotation: Subtype: Link Rect: 332, 708, 368, 719 Annotation: Subtype: Link Rect: 386, 682, 424, 693 Annotation: Subtype: Link Rect: 430, 682, 466, 693 Annotation: Subtype: Link Rect: 247, 631, 285, 642 Annotation: Subtype: Link Rect: 461, 566, 498, 577 Annotation: Subtype: Link Rect: 154, 528, 192, 538 Annotation: Subtype: Link Rect: 461, 502, 498, 512 Annotation: Subtype: Link Rect: 405, 463, 443, 474 Annotation: Subtype: Link Rect: 449, 463, 485, 474 Annotation: Subtype: Link Rect: 299, 437, 336, 448 Annotation: Subtype: Link Rect: 343, 437, 379, 448 Annotation: Subtype: Link Rect: 399, 412, 436, 422 Annotation: Subtype: Link Rect: 443, 412, 479, 422 Annotation: Subtype: Link Rect: 403, 385, 441, 396 Annotation: Subtype: Link Rect: 447, 385, 483, 396 Annotation: Subtype: Link Rect: 428, 360, 465, 370 Annotation: Subtype: Link Rect: 287, 334, 324, 345 Annotation: Subtype: Link Rect: 330, 334, 366, 345 Annotation: Subtype: Link Rect: 227, 295, 264, 306 Annotation: Subtype: Link Rect: 271, 295, 307, 306 Annotation: Subtype: Link Rect: 145, 257, 182, 267 Annotation: Subtype: Link Rect: 189, 257, 225, 267 Annotation: Subtype: Link Rect: 297, 217, 335, 228 Annotation: Subtype: Link Rect: 459, 179, 497, 190 Annotation: Subtype: Link Rect: 267, 140, 304, 151 Annotation: Subtype: Link Rect: 330, 114, 367, 125 Annotation: Subtype: Link Rect: 145, 76, 182, 86 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 275, 727, 312, 738 Annotation: Subtype: Link Rect: 318, 727, 354, 738 Annotation: Subtype: Link Rect: 100, 689, 137, 699 Annotation: Subtype: Link Rect: 143, 689, 179, 699 Annotation: Subtype: Link Rect: 356, 663, 394, 673 Annotation: Subtype: Link Rect: 141, 625, 178, 635 Annotation: Subtype: Link Rect: 428, 598, 466, 609 Annotation: Subtype: Link Rect: 150, 547, 187, 557 Annotation: Subtype: Link Rect: 207, 521, 245, 531 Annotation: Subtype: Link Rect: 177, 496, 214, 506 Annotation: Subtype: Link Rect: 212, 470, 250, 480 Annotation: Subtype: Link Rect: 412, 443, 449, 454 Annotation: Subtype: Link Rect: 145, 405, 183, 415 Annotation: Subtype: Link Rect: 421, 379, 458, 389 Annotation: Subtype: Link Rect: 464, 379, 500, 389 Annotation: Subtype: Link Rect: 322, 340, 359, 351 Annotation: Subtype: Link Rect: 100, 315, 137, 325 Annotation: Subtype: Link Rect: 143, 315, 179, 325 Annotation: Subtype: Link Rect: 193, 276, 231, 286 Annotation: Subtype: Link Rect: 237, 276, 273, 286 Annotation: Subtype: Link Rect: 225, 237, 262, 247 Annotation: Subtype: Link Rect: 140, 199, 178, 209 Annotation: Subtype: Link Rect: 181, 160, 219, 170 Annotation: Subtype: Link Rect: 257, 134, 294, 144 Annotation: Subtype: Link Rect: 100, 95, 137, 105 Annotation: Subtype: Link Rect: 143, 95, 179, 105 Annotation: Subtype: Link Rect: 395, 69, 432, 80 Annotation: Subtype: Link Rect: 438, 69, 474, 80 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 145, 715, 183, 725 Annotation: Subtype: Link Rect: 189, 715, 225, 725 Annotation: Subtype: Link Rect: 168, 689, 206, 699 Annotation: Subtype: Link Rect: 212, 689, 248, 699 Annotation: Subtype: Link Rect: 246, 651, 283, 661 Annotation: Subtype: Link Rect: 412, 624, 450, 635 Annotation: Subtype: Link Rect: 214, 586, 251, 596 Annotation: Subtype: Link Rect: 127, 547, 165, 557 Annotation: Subtype: Link Rect: 232, 521, 270, 531 Annotation: Subtype: Link Rect: 209, 482, 246, 493 Annotation: Subtype: Link Rect: 265, 456, 303, 467 Annotation: Subtype: Link Rect: 309, 456, 345, 467 Annotation: Subtype: Link Rect: 235, 430, 272, 441 Annotation: Subtype: Link Rect: 278, 430, 314, 441 Annotation: Subtype: Link Rect: 76, 388, 166, 419 Annotation: Subtype: Link Rect: 234, 382, 407, 393 Checksum: 447d3456 Type: CRC32 Checksum: c61dd5de9e041247f5ec822dbc42ffe7 Type: MD5 Checksum: 0fb238732db83f41b1044eccbd8a7281a95c665e Type: SHA-1