925621490d586158da137d81df862839 pmc_32376137.pdf 28b6fb9537c7f949f73e59612c75aff77e944a02 pmc_32376137.pdf 386ca5b2ffb7fa0fe6f3eb2e2a1e7fdd63977eabe797340e75014f420da75b29 pmc_32376137.pdf Producer: PyPDF2 Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 612 x 792 pts (letter) Page rot: 0 File size: 440009 bytes Optimized: no PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ArialMT TrueType WinAnsi no no no 13 0 ALAFAJ+AdvOT863180fb Type 1C WinAnsi yes yes no 104 0 ALAHCF+AdvOT863180fb+fb Type 1C Custom yes yes yes 107 0 ALAHDF+AdvP4DF60E Type 1C WinAnsi yes yes no 112 0 ALAFAK+Times-Roman Type 1C WinAnsi yes yes no 115 0 ALAFAL+AdvOT863180fb+20 Type 1C WinAnsi yes yes no 118 0 ALAFBM+AdvOT18499c10.B Type 1C WinAnsi yes yes no 121 0 ALAFCN+AdvP4DF612 Type 1C WinAnsi yes yes no 124 0 ALAFLK+AdvOTf2586c63.I Type 1C WinAnsi yes yes no 127 0 ALAGFH+AdvOTf2586c63.I+20 Type 1C WinAnsi yes yes no 130 0 ALAHAE+AdvP8CAA Type 1C WinAnsi yes yes no 133 0 ALAHBE+AdvPi2 Type 1C WinAnsi yes yes no 136 0 ALAMFF+AdvP4C4E51 Type 1C WinAnsi yes yes no 155 0 ALAMKE+AdvP4C4E74 Type 1C Custom yes yes no 158 0 ALAOPG+AdvOT18499c10.B+20 Type 1C WinAnsi yes yes no 162 0 ALAPBG+Calibri Type 1C Custom yes yes yes 165 0 ALBOFD+AdvOT1be73566.BI Type 1C WinAnsi yes yes no 217 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 04:10:26 CEST RepresentationInformation: pmc_32376137.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 11:46:27 CEST Size: 440009 Format: PDF Version: 1.3 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 267 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Info: Producer: PyPDF2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode FilterPipeline: CCITTFaxDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 292 ImageHeight: 323 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Interpolate: false Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 296 ImageHeight: 396 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 120 ImageHeight: 120 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/tiff CompressionScheme: CCITT Group 4 ImageWidth: 1618 ImageHeight: 446 BitsPerSample: 1 BitsPerSampleUnit: integer ImageMask: true Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2067 ImageHeight: 69 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2067 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: ALAGFH+AdvOTf2586c63.I+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: ALAGFH+AdvOTf2586c63.I+20 Flags: Nonsymbolic FontBBox: -48, -211, 887, 789 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAOPG+AdvOT18499c10.B+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: ALAOPG+AdvOT18499c10.B+20 Flags: Nonsymbolic FontBBox: 14, -211, 1131, 789 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAHAE+AdvP8CAA FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: ALAHAE+AdvP8CAA Flags: Nonsymbolic FontBBox: -145, -239, 1000, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAPBG+Calibri FontSubset: true FirstChar: 2 LastChar: 222 FontDescriptor: FontName: ALAPBG+Calibri Flags: Symbolic FontBBox: -503, -307, 1240, 964 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ALAHBE+AdvPi2 FontSubset: true FirstChar: 36 LastChar: 36 FontDescriptor: FontName: ALAHBE+AdvPi2 Flags: Nonsymbolic FontBBox: 16, -335, 981, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAFAJ+AdvOT863180fb FontSubset: true FirstChar: 37 LastChar: 252 FontDescriptor: FontName: ALAFAJ+AdvOT863180fb Flags: Serif, Nonsymbolic FontBBox: -76, -251, 1042, 986 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAHCF+AdvOT863180fb+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: ALAHCF+AdvOT863180fb+fb Flags: Symbolic FontBBox: 48, 0, 896, 789 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ALAHDF+AdvP4DF60E FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: ALAHDF+AdvP4DF60E Flags: Serif, Nonsymbolic FontBBox: -104, -239, 1041, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAFAK+Times-Roman FontSubset: true FirstChar: 32 LastChar: 32 FontDescriptor: FontName: ALAFAK+Times-Roman Flags: Serif, Nonsymbolic FontBBox: -168, -218, 1000, 898 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAFAL+AdvOT863180fb+20 FontSubset: true FirstChar: 146 LastChar: 151 FontDescriptor: FontName: ALAFAL+AdvOT863180fb+20 Flags: Nonsymbolic FontBBox: 15, -213, 956, 789 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAFBM+AdvOT18499c10.B FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: ALAFBM+AdvOT18499c10.B Flags: Serif, Nonsymbolic FontBBox: -98, -250, 1049, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALBOFD+AdvOT1be73566.BI FontSubset: true FirstChar: 47 LastChar: 117 FontDescriptor: FontName: ALBOFD+AdvOT1be73566.BI Flags: Nonsymbolic FontBBox: -175, -248, 1120, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAMFF+AdvP4C4E51 FontSubset: true FirstChar: 62 LastChar: 62 FontDescriptor: FontName: ALAMFF+AdvP4C4E51 Flags: Nonsymbolic FontBBox: -31, -239, 1041, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAFCN+AdvP4DF612 FontSubset: true FirstChar: 42 LastChar: 248 FontDescriptor: FontName: ALAFCN+AdvP4DF612 Flags: Serif, Nonsymbolic FontBBox: -145, -229, 1083, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ALAMKE+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: ALAMKE+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: ALAFLK+AdvOTf2586c63.I FontSubset: true FirstChar: 38 LastChar: 252 FontDescriptor: FontName: ALAFLK+AdvOTf2586c63.I Flags: Serif, Nonsymbolic FontBBox: -141, -232, 1053, 972 FontFile3: true Encoding: WinAnsiEncoding TrueType: Font: Name: F1 BaseFont: ArialMT FirstChar: 32 LastChar: 121 FontDescriptor: FontName: ArialMT Flags: Nonsymbolic FontBBox: -665, -210, 2000, 728 Encoding: WinAnsiEncoding Pages: Page: Sequence: 1 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 126, 499, 133, 510 Flags: Print Destination: External Annotation: Subtype: Link Rect: 133, 494, 226, 505 Flags: Print Destination: External Annotation: Subtype: Link Rect: 226, 494, 324, 505 Flags: Print Destination: External Annotation: Subtype: Link Rect: 324, 494, 408, 505 Flags: Print Destination: External Annotation: Subtype: Link Rect: 408, 494, 500, 505 Flags: Print Destination: External Annotation: Subtype: Link Rect: 500, 494, 511, 505 Flags: Print Destination: External Annotation: Subtype: Link Rect: 128, 485, 132, 496 Flags: Print Destination: External Annotation: Subtype: Link Rect: 132, 480, 253, 491 Flags: Print Destination: External Annotation: Subtype: Link Rect: 253, 480, 338, 491 Flags: Print Destination: External Annotation: Subtype: Link Rect: 338, 480, 393, 491 Flags: Print Destination: External Annotation: Subtype: Link Rect: 393, 485, 398, 496 Flags: Print Destination: External Annotation: Subtype: Link Rect: 398, 480, 533, 491 Flags: Print Destination: External Annotation: Subtype: Link Rect: 183, 466, 371, 477 Flags: Print Destination: External Annotation: Subtype: Link Rect: 371, 466, 489, 477 Flags: Print Destination: External Annotation: Subtype: Link Rect: 489, 466, 501, 477 Flags: Print Destination: External Annotation: Subtype: Link Rect: 160, 452, 238, 463 Flags: Print Destination: External Annotation: Subtype: Link Rect: 238, 456, 245, 467 Flags: Print Destination: External Annotation: Subtype: Link Rect: 245, 452, 384, 463 Flags: Print Destination: External Annotation: Subtype: Link Rect: 384, 452, 487, 463 Flags: Print Destination: External Annotation: Subtype: Link Rect: 487, 452, 497, 463 Flags: Print Destination: External Annotation: Subtype: Link Rect: 162, 437, 231, 448 Flags: Print Destination: External Annotation: Subtype: Link Rect: 231, 437, 323, 448 Flags: Print Destination: External Annotation: Subtype: Link Rect: 323, 437, 412, 448 Flags: Print Destination: External Annotation: Subtype: Link Rect: 412, 437, 511, 448 Flags: Print Destination: External Annotation: Subtype: Link Rect: 511, 437, 518, 448 Flags: Print Destination: External Annotation: Subtype: Link Rect: 140, 423, 240, 434 Flags: Print Destination: External Annotation: Subtype: Link Rect: 240, 428, 246, 439 Flags: Print Destination: External Annotation: Subtype: Link Rect: 246, 423, 344, 434 Flags: Print Destination: External Annotation: Subtype: Link Rect: 344, 423, 433, 434 Flags: Print Destination: External Annotation: Subtype: Link Rect: 433, 423, 532, 434 Flags: Print Destination: External Annotation: Subtype: Link Rect: 532, 423, 542, 434 Flags: Print Destination: External Annotation: Subtype: Link Rect: 129, 414, 141, 425 Flags: Print Destination: External Annotation: Subtype: Link Rect: 141, 409, 257, 420 Flags: Print Destination: External Annotation: Subtype: Link Rect: 257, 409, 352, 420 Flags: Print Destination: External Annotation: Subtype: Link Rect: 352, 409, 458, 420 Flags: Print Destination: External Annotation: Subtype: Link Rect: 458, 409, 475, 420 Flags: Print Destination: External Annotation: Subtype: Link Rect: 137, 395, 260, 406 Flags: Print Destination: External Annotation: Subtype: Link Rect: 260, 395, 339, 406 Flags: Print Destination: External Annotation: Subtype: Link Rect: 339, 395, 435, 406 Flags: Print Destination: External Annotation: Subtype: Link Rect: 435, 395, 446, 406 Flags: Print Destination: External Annotation: Subtype: Link Rect: 152, 381, 253, 392 Flags: Print Destination: External Annotation: Subtype: Link Rect: 253, 381, 488, 392 Flags: Print Destination: External Annotation: Subtype: Link Rect: 173, 367, 259, 378 Flags: Print Destination: External Annotation: Subtype: Link Rect: 259, 367, 382, 378 Flags: Print Destination: External Annotation: Subtype: Link Rect: 382, 367, 479, 378 Flags: Print Destination: External Annotation: Subtype: Link Rect: 479, 367, 493, 378 Flags: Print Destination: External Annotation: Subtype: Link Rect: 121, 357, 130, 368 Flags: Print Destination: External Annotation: Subtype: Link Rect: 130, 353, 215, 363 Flags: Print Destination: External Annotation: Subtype: Link Rect: 215, 353, 467, 363 Flags: Print Destination: External Annotation: Subtype: Link Rect: 222, 753, 377, 759 Flags: Print Annotation: Subtype: Link Rect: 270, 86, 338, 93 Flags: Print Annotation: Subtype: Link Rect: 51, 58, 199, 65 Flags: Print Annotation: Subtype: Link Rect: 519, 37, 547, 65 Flags: Print Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 206, 326, 217, 335 Flags: Print Destination: External Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 122, 487, 133, 496 Flags: Print Destination: External Annotation: Subtype: Link Rect: 72, 407, 100, 415 Flags: Print Destination: External Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 333, 578, 336, 585 Flags: Print Destination: External Annotation: Subtype: Link Rect: 471, 517, 480, 524 Flags: Print Destination: External Annotation: Subtype: Link Rect: 519, 431, 541, 438 Flags: Print Destination: External Annotation: Subtype: Link Rect: 133, 412, 155, 419 Flags: Print Destination: External Annotation: Subtype: Link Rect: 380, 401, 394, 408 Flags: Print Destination: External Annotation: Subtype: Link Rect: 347, 263, 356, 270 Flags: Print Destination: External Annotation: Subtype: Link Rect: 361, 263, 440, 270 Flags: Print Annotation: Subtype: Link Rect: 55, 255, 230, 262 Flags: Print Annotation: Subtype: Link Rect: 199, 225, 213, 232 Flags: Print Destination: External Annotation: Subtype: Link Rect: 496, 152, 510, 159 Flags: Print Destination: External Annotation: Subtype: Link Rect: 186, 136, 196, 143 Flags: Print Destination: External Annotation: Subtype: Link Rect: 209, 118, 218, 125 Flags: Print Destination: External Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 211, 187, 240, 195 Flags: Print Destination: External Annotation: Subtype: Link Rect: 430, 256, 459, 264 Flags: Print Destination: External Annotation: Subtype: Link Rect: 464, 256, 476, 264 Flags: Print Destination: External Annotation: Subtype: Link Rect: 498, 163, 517, 172 Flags: Print Destination: External Annotation: Subtype: Link Rect: 308, 106, 320, 114 Flags: Print Destination: External Annotation: Subtype: Link Rect: 464, 48, 494, 56 Flags: Print Destination: External Annotation: Subtype: Link Rect: 179, 644, 189, 651 Flags: Print Destination: External Annotation: Subtype: Link Rect: 478, 521, 491, 527 Flags: Print Destination: External Annotation: Subtype: Link Rect: 310, 513, 323, 519 Flags: Print Destination: External Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 242, 649, 254, 658 Flags: Print Destination: External Annotation: Subtype: Link Rect: 152, 615, 164, 623 Flags: Print Destination: External Annotation: Subtype: Link Rect: 81, 499, 92, 507 Flags: Print Destination: External Annotation: Subtype: Link Rect: 259, 441, 270, 450 Flags: Print Destination: External Annotation: Subtype: Link Rect: 139, 349, 168, 357 Flags: Print Destination: External Annotation: Subtype: Link Rect: 175, 349, 196, 357 Flags: Print Destination: External Annotation: Subtype: Link Rect: 158, 326, 173, 334 Flags: Print Destination: External Annotation: Subtype: Link Rect: 88, 314, 104, 323 Flags: Print Destination: External Annotation: Subtype: Link Rect: 195, 164, 211, 172 Flags: Print Destination: External Annotation: Subtype: Link Rect: 197, 71, 213, 80 Flags: Print Destination: External Annotation: Subtype: Link Rect: 434, 615, 464, 623 Flags: Print Destination: External Annotation: Subtype: Link Rect: 470, 615, 497, 623 Flags: Print Destination: External Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 448, 152, 547, 161 Flags: Print Annotation: Subtype: Link Rect: 308, 141, 388, 149 Flags: Print Annotation: Subtype: Link Rect: 434, 94, 548, 101 Flags: Print Annotation: Subtype: Link Rect: 326, 83, 384, 90 Flags: Print Annotation: Subtype: Link Rect: 325, 73, 547, 79 Flags: Print Annotation: Subtype: Link Rect: 325, 62, 547, 69 Flags: Print Annotation: Subtype: Link Rect: 325, 51, 484, 58 Flags: Print Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 224, 709, 286, 716 Flags: Print Annotation: Subtype: Link Rect: 63, 699, 167, 706 Flags: Print Annotation: Subtype: Link Rect: 136, 678, 286, 685 Flags: Print Annotation: Subtype: Link Rect: 63, 667, 235, 674 Flags: Print Annotation: Subtype: Link Rect: 63, 657, 286, 664 Flags: Print Annotation: Subtype: Link Rect: 63, 646, 193, 653 Flags: Print Annotation: Subtype: Link Rect: 234, 614, 286, 621 Flags: Print Annotation: Subtype: Link Rect: 63, 604, 162, 611 Flags: Print Annotation: Subtype: Link Rect: 220, 572, 286, 579 Flags: Print Annotation: Subtype: Link Rect: 63, 562, 265, 569 Flags: Print Annotation: Subtype: Link Rect: 113, 530, 275, 537 Flags: Print Annotation: Subtype: Link Rect: 63, 519, 286, 526 Flags: Print Annotation: Subtype: Link Rect: 63, 509, 286, 516 Flags: Print Annotation: Subtype: Link Rect: 63, 498, 140, 505 Flags: Print Annotation: Subtype: Link Rect: 134, 466, 286, 473 Flags: Print Annotation: Subtype: Link Rect: 64, 456, 88, 463 Flags: Print Annotation: Subtype: Link Rect: 94, 424, 259, 431 Flags: Print Annotation: Subtype: Link Rect: 368, 699, 543, 706 Flags: Print Annotation: Subtype: Link Rect: 321, 688, 344, 695 Flags: Print Annotation: Subtype: Link Rect: 321, 678, 543, 685 Flags: Print Annotation: Subtype: Link Rect: 321, 667, 543, 674 Flags: Print Annotation: Subtype: Link Rect: 321, 657, 422, 664 Flags: Print Annotation: Subtype: Link Rect: 321, 646, 543, 653 Flags: Print Annotation: Subtype: Link Rect: 321, 635, 543, 642 Flags: Print Annotation: Subtype: Link Rect: 321, 625, 541, 632 Flags: Print Annotation: Subtype: Link Rect: 400, 604, 531, 611 Flags: Print Annotation: Subtype: Link Rect: 393, 583, 543, 590 Flags: Print Annotation: Subtype: Link Rect: 321, 572, 426, 579 Flags: Print Annotation: Subtype: Link Rect: 320, 562, 543, 569 Flags: Print Annotation: Subtype: Link Rect: 320, 551, 350, 558 Flags: Print Annotation: Subtype: Link Rect: 439, 519, 543, 526 Flags: Print Annotation: Subtype: Link Rect: 321, 509, 394, 516 Flags: Print Annotation: Subtype: Link Rect: 407, 477, 540, 484 Flags: Print Annotation: Subtype: Link Rect: 321, 466, 543, 473 Flags: Print Annotation: Subtype: Link Rect: 321, 456, 543, 463 Flags: Print Annotation: Subtype: Link Rect: 321, 445, 422, 452 Flags: Print Checksum: e6081920 Type: CRC32 Checksum: 925621490d586158da137d81df862839 Type: MD5 Checksum: 28b6fb9537c7f949f73e59612c75aff77e944a02 Type: SHA-1 Checksum: 386ca5b2ffb7fa0fe6f3eb2e2a1e7fdd63977eabe797340e75014f420da75b29 Type: SHA-256