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Title:          RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response
Subject:        Veterinary Research, https://doi.org/10.1186/s13567-020-00784-y
Author:         Raquel Lama 
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     Item: 
      Title: RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response
      Children: 
       Item: 
        Title: Abstract 
       Item: 
        Title: Introduction
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Fish and virus
         Item: 
          Title: Fish infection and sampling for RNA-Seq
         Item: 
          Title: RNA isolation and high-throughput transcriptome sequencing
         Item: 
          Title: Raw data cleaning, de novo assembly and gene annotation
         Item: 
          Title: RNA-Seq analysis
         Item: 
          Title: NNV detection and RNA-Seq validation by quantitative PCR (qPCR)
         Item: 
          Title: Cortisol implants and nodavirus challenge
         Item: 
          Title: Respiratory burst activity determined by chemiluminescence assays
         Item: 
          Title: Inactivation of NNV using hydrogen peroxide
         Item: 
          Title: Intracellular calcium measurement with FLUO-4 AM
         Item: 
          Title: Cell treatment with calcium channel inhibitors and calcium chelators
         Item: 
          Title: Statistical analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Effects of NNV challenge in juvenile sea bass
         Item: 
          Title: Transcriptome modulation in European sea bass after NNV infection
         Item: 
          Title: Modulation of immune-related genes after NNV infection
         Item: 
          Title: Nodavirus induces alterations in the HPI axis
          Children: 
           Item: 
            Title: HPI axis modulation in the brain
           Item: 
            Title: HPI axis modulation in the head kidney
         Item: 
          Title: Effect of cortisol on defence against NNV
         Item: 
          Title: ROS production modulation during nodavirus infection
         Item: 
          Title: Calcium modifications interfere with ROS production and nodavirus replication
         Item: 
          Title: Validation of the RNA-Seq results
       Item: 
        Title: Discussion
       Item: 
        Title: Acknowledgements
       Item: 
        Title: References
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                           <pdfaProperty:description>CrossMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
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                  <pdfaSchema:prefix>prism</pdfaSchema:prefix>
                  <pdfaSchema:schema>Prism Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.</pdfaProperty:description>
                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). </pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Volume number</pdfaProperty:description>
                           <pdfaProperty:name>volume</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Issue number</pdfaProperty:description>
                           <pdfaProperty:name>number</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
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                           <pdfaProperty:description>Starting page</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                           <pdfaProperty:description>Ending page</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. </pdfaProperty:description>
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                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”</pdfaProperty:description>
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                           <pdfaProperty:name>copyright</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
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                           <pdfaProperty:name>Trapped</pdfaProperty:name>
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                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
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                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
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                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
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                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
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                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
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                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
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                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
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                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
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                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
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                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
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                           <pdfaProperty:valueType>Bag AuthorInformation</pdfaProperty:valueType>
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                           <pdfaProperty:description>Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.</pdfaProperty:description>
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                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
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AM = Accepted Manuscript
P = Proof
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                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
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   Type: CRC32
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   Type: MD5
  Checksum: f0a1a65f16c99400838a077aa840d6a8a1f262da
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