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Title:           Update of the recommendations for the determination of biomarkers in colorectal carcinoma: National Consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology
Subject:         Clinical and Translational Oncology, https://doi.org/10.1007/s12094-020-02357-z
Keywords:        Diagnosis,Neoplastic disease,Gastrointestinal,Genetic prognosis,Tumour
Author:          P. García-Alfonso 
Creator:         Springer
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     Item: 
      Title: Update of the recommendations for the determination of biomarkers in colorectal carcinoma: National Consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology
      Children: 
       Item: 
        Title: Abstract
       Item: 
        Title: Introduction
       Item: 
        Title: Clinical aspects
        Children: 
         Item: 
          Title: Molecular markers of hereditary CRC susceptibility
          Children: 
           Item: 
            Title: Lynch syndrome
           Item: 
            Title: Polyopsis syndromes
         Item: 
          Title: Molecular markers of localized CRC​
         Item: 
          Title: Essential molecular markers of advanced CRC​
          Children: 
           Item: 
            Title: RAS mutations
           Item: 
            Title: BRAF mutations
           Item: 
            Title: MSI
         Item: 
          Title: Recommended molecular markers of advanced CRC​
       Item: 
        Title: Pathological aspects
        Children: 
         Item: 
          Title: What is relevant in the pathology diagnosis of CRC?
          Children: 
           Item: 
            Title: Tumour budding (TB) and poorly differentiated clusters (PDC)
           Item: 
            Title: Lymph node staging
         Item: 
          Title: What are the requirements of an optimal sample?
          Children: 
           Item: 
            Title: Preservation of tumour material
           Item: 
            Title: Minimum sufficient quantity
         Item: 
          Title: Which techniques are most appropriate for the determination of each biomarker?
          Children: 
           Item: 
            Title: RAS mutations
           Item: 
            Title: MSI
           Item: 
            Title: Alterations in HER2
           Item: 
            Title: NTRK rearrangements
       Item: 
        Title: What is the current and future role of NGS in CRC?
       Item: 
        Title: What are the current and future roles of liquid biopsy in CRC?
       Item: 
        Title: Conclusions
       Item: 
        Title: Acknowledgements 
       Item: 
        Title: References
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    Title: Update of the recommendations for the determination of biomarkers in colorectal carcinoma: National Consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology
    Author: P. García-Alfonso 
    Subject: Clinical and Translational Oncology, https://doi.org/10.1007/s12094-020-02357-z
    Keywords: Diagnosis,Neoplastic disease,Gastrointestinal,Genetic prognosis,Tumour
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