631394ea2faa73aaf727f6cce13df04e pmc_32471226.pdf 7f415ae2caae3a79528f3f0b921874ec2d1d1e33 pmc_32471226.pdf a010324d819c076654f9db8c8bdfa65f0ca631eab4606dda5f7cd47a46fd5bc2 pmc_32471226.pdf Producer: iText® 7.1.1 ©2000-2018 iText Group NV (AGPL-version) CreationDate: Mon Jun 29 13:15:26 2020 CEST ModDate: Mon Jun 29 13:15:26 2020 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1161081 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XHDYZV+VnURWPalladioL Type 1 Custom yes yes no 10 0 TPNQKM+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 GSJRIN+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 YRXZUZ+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 SVVJCD+Rpxr Type 1 Builtin yes yes no 28 0 KZZFXQ+Pxsy Type 1 Builtin yes yes no 32 0 FYYAHQ+VnURWPalladioL-Bold Type 1 Custom yes yes no 36 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 44 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 47 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 69 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 73 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 77 0 TGMEOR+Rpcxr Type 1 Builtin yes yes no 84 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes no 92 0 ABCDEE+Palatino Linotype TrueType WinAnsi yes yes no 100 0 ABCDEE+Palatino Linotype,Italic TrueType WinAnsi yes yes no 104 0 ABCDEE+Palatino Linotype,Bold TrueType WinAnsi yes yes no 108 0 ABCDEE+Cambria TrueType WinAnsi yes yes no 112 0 ABCDEE+Palatino Linotype,BoldItalic TrueType WinAnsi yes yes no 116 0 CKBPVA+EURM10 Type 1 Builtin yes yes no 126 0 ABCDEE+Palatino Linotype TrueType WinAnsi yes yes no 134 0 ABCDEE+Palatino Linotype,Italic TrueType WinAnsi yes yes no 138 0 ABCDEE+Palatino Linotype,Bold TrueType WinAnsi yes yes no 142 0 ABCDEE+Palatino Linotype CID TrueType Identity-H yes yes yes 146 0 ABCDEE+Cambria TrueType WinAnsi yes yes no 153 0 ABCDEE+Cambria CID TrueType Identity-H yes yes yes 157 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-18 06:35:33 CET RepresentationInformation: pmc_32471226.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-07-27 03:47:47 CEST Size: 1161081 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 270 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Children: Item: Title: Surgical Procedure and Randomization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Radiological Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Clinical Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Info: Producer: iText® 7.1.1 ©2000-2018 iText Group NV (AGPL-version) CreationDate: Mon Jun 29 13:15:26 CEST 2020 ModDate: Mon Jun 29 13:15:26 CEST 2020 ID: 0x270aea3365264e8526ac4d5eef2b3170, 0x270aea3365264e8526ac4d5eef2b3170 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: KZZFXQ+Pxsy FontSubset: true FirstChar: 14 LastChar: 14 FontDescriptor: FontName: KZZFXQ+Pxsy Flags: Symbolic FontBBox: -21, -994, 1292, 912 FontFile: true Font: BaseFont: GSJRIN+URWPalladioL-Bold FontSubset: true FirstChar: 2 LastChar: 122 FontDescriptor: FontName: GSJRIN+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: FYYAHQ+VnURWPalladioL-Bold FontSubset: true FirstChar: 161 LastChar: 243 FontDescriptor: FontName: FYYAHQ+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: TGMEOR+Rpcxr FontSubset: true FirstChar: 169 LastChar: 174 FontDescriptor: FontName: TGMEOR+Rpcxr Flags: Symbolic FontBBox: -212, -286, 1344, 973 FontFile: true Font: BaseFont: YRXZUZ+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 151 FontDescriptor: FontName: YRXZUZ+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XHDYZV+VnURWPalladioL FontSubset: true FirstChar: 225 LastChar: 226 FontDescriptor: FontName: XHDYZV+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: SVVJCD+Rpxr FontSubset: true FirstChar: 11 LastChar: 61 FontDescriptor: FontName: SVVJCD+Rpxr Flags: Symbolic FontBBox: -40, -283, 904, 728 FontFile: true Font: BaseFont: WBVKDJ+URWPalladioL-BoldItal FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: WBVKDJ+URWPalladioL-BoldItal Flags: Symbolic FontBBox: -170, -300, 1073, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CKBPVA+EURM10 FontSubset: true FirstChar: 11 LastChar: 11 FontDescriptor: FontName: CKBPVA+EURM10 Flags: Symbolic FontBBox: -32, -243, 1060, 720 FontFile: true Font: BaseFont: TPNQKM+URWPalladioL-Ital FontSubset: true FirstChar: 46 LastChar: 122 FontDescriptor: FontName: TPNQKM+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 75, 757, 217, 793 Annotation: Subtype: Link Rect: 474, 757, 519, 793 Annotation: Subtype: Link Rect: 450, 620, 461, 633 Annotation: Subtype: Link Rect: 222, 105, 229, 114 ActionDest: 171 Annotation: Subtype: Link Rect: 232, 104, 239, 114 ActionDest: 171 Annotation: Subtype: Link Rect: 181, 38, 251, 50 Annotation: Subtype: Link Rect: 418, 38, 519, 50 Annotation: Subtype: Link Rect: 466, 467, 518, 486 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 234, 743, 241, 752 ActionDest: 171 Annotation: Subtype: Link Rect: 244, 742, 251, 752 ActionDest: 171 Annotation: Subtype: Link Rect: 252, 702, 259, 711 ActionDest: 171 Annotation: Subtype: Link Rect: 136, 688, 143, 698 ActionDest: 171 Annotation: Subtype: Link Rect: 188, 607, 195, 617 ActionDest: 171 Annotation: Subtype: Link Rect: 217, 594, 224, 603 ActionDest: 171 Annotation: Subtype: Link Rect: 378, 580, 385, 590 ActionDest: 171 Annotation: Subtype: Link Rect: 152, 553, 159, 562 ActionDest: 171 Annotation: Subtype: Link Rect: 162, 553, 174, 562 ActionDest: 171 Annotation: Subtype: Link Rect: 116, 499, 128, 508 ActionDest: 171 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 420, 740, 426, 752 ActionDest: 88 Annotation: Subtype: Link Rect: 369, 699, 376, 711 ActionDest: 88 Annotation: Subtype: Link Rect: 329, 109, 341, 119 ActionDest: 171 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 423, 699, 430, 711 ActionDest: 122 Annotation: Subtype: Link Rect: 358, 688, 370, 698 ActionDest: 171 Annotation: Subtype: Link Rect: 393, 285, 405, 295 ActionDest: 171 Annotation: Subtype: Link Rect: 503, 285, 515, 295 ActionDest: 171 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 121, 680, 128, 692 ActionDest: 165 Annotation: Subtype: Link Rect: 172, 653, 179, 665 ActionDest: 165 Annotation: Subtype: Link Rect: 124, 303, 131, 314 ActionDest: 165 Annotation: Subtype: Link Rect: 174, 87, 186, 96 ActionDest: 171 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 323, 729, 335, 738 ActionDest: 171 Annotation: Subtype: Link Rect: 350, 688, 362, 698 ActionDest: 171 Annotation: Subtype: Link Rect: 196, 607, 208, 617 ActionDest: 171 Annotation: Subtype: Link Rect: 379, 580, 390, 590 ActionDest: 171 Annotation: Subtype: Link Rect: 391, 580, 403, 590 ActionDest: 174 Annotation: Subtype: Link Rect: 110, 553, 122, 562 ActionDest: 171 Annotation: Subtype: Link Rect: 125, 553, 137, 562 ActionDest: 171 Annotation: Subtype: Link Rect: 138, 553, 149, 562 ActionDest: 174 Annotation: Subtype: Link Rect: 503, 526, 515, 535 ActionDest: 174 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 158, 683, 196, 693 Annotation: Subtype: Link Rect: 202, 683, 238, 693 Annotation: Subtype: Link Rect: 401, 656, 438, 667 Annotation: Subtype: Link Rect: 444, 656, 480, 667 Annotation: Subtype: Link Rect: 149, 631, 187, 641 Annotation: Subtype: Link Rect: 193, 631, 229, 641 Annotation: Subtype: Link Rect: 200, 592, 238, 602 Annotation: Subtype: Link Rect: 244, 592, 280, 602 Annotation: Subtype: Link Rect: 440, 566, 478, 577 Annotation: Subtype: Link Rect: 100, 541, 137, 551 Annotation: Subtype: Link Rect: 417, 514, 455, 525 Annotation: Subtype: Link Rect: 242, 488, 279, 499 Annotation: Subtype: Link Rect: 479, 462, 516, 473 Annotation: Subtype: Link Rect: 427, 437, 464, 448 Annotation: Subtype: Link Rect: 378, 411, 415, 422 Annotation: Subtype: Link Rect: 421, 411, 457, 422 Annotation: Subtype: Link Rect: 297, 372, 335, 383 Annotation: Subtype: Link Rect: 341, 372, 377, 383 Annotation: Subtype: Link Rect: 163, 347, 201, 357 Annotation: Subtype: Link Rect: 207, 347, 243, 357 Annotation: Subtype: Link Rect: 181, 321, 219, 331 Annotation: Subtype: Link Rect: 478, 295, 516, 305 Annotation: Subtype: Link Rect: 409, 269, 446, 280 Annotation: Subtype: Link Rect: 219, 243, 257, 254 Annotation: Subtype: Link Rect: 100, 192, 137, 202 Annotation: Subtype: Link Rect: 367, 165, 404, 176 Annotation: Subtype: Link Rect: 298, 140, 336, 151 Annotation: Subtype: Link Rect: 342, 140, 378, 151 Annotation: Subtype: Link Rect: 368, 114, 406, 125 Annotation: Subtype: Link Rect: 412, 114, 448, 125 Annotation: Subtype: Link Rect: 333, 88, 371, 99 Annotation: Subtype: Link Rect: 377, 88, 413, 99 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 471, 740, 519, 751 Annotation: Subtype: Link Rect: 97, 727, 249, 738 Annotation: Subtype: Link Rect: 132, 702, 168, 712 Annotation: Subtype: Link Rect: 250, 675, 288, 686 Annotation: Subtype: Link Rect: 294, 675, 330, 686 Annotation: Subtype: Link Rect: 76, 633, 166, 664 Annotation: Subtype: Link Rect: 234, 628, 407, 639 Checksum: 4ab8d11a Type: CRC32 Checksum: 631394ea2faa73aaf727f6cce13df04e Type: MD5 Checksum: 7f415ae2caae3a79528f3f0b921874ec2d1d1e33 Type: SHA-1