6de332189540c8f3bbe6992ffe92fe8e pmc_32572647.pdf 8053f7351c7db4de383a5d5053f798ccde105353 pmc_32572647.pdf 1111f2b7ea9728cf2f92ace7bcc4870db2f99a364c904ea6b5a35c73cef80241 pmc_32572647.pdf Title: Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review Subject: Annals of Intensive Care, https://doi.org/10.1186/s13613-020-00697-1 Keywords: Endothelial cell,Glycocalyx,Albumin,Microcirculation,Sepsis Author: Cesar Aldecoa Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Wed Jun 17 12:57:27 2020 CEST ModDate: Mon Jun 22 11:28:47 2020 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1527082 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-Regular Type 1C Custom yes no yes 29 0 MyriadPro-Bold Type 1C Custom yes no yes 36 0 MyriadPro-It Type 1C Custom yes no yes 31 0 MyriadPro-Semibold Type 1C Custom yes no yes 34 0 MyriadPro-Light Type 1C Custom yes no yes 35 0 WarnockPro-Regular Type 1C Custom yes no yes 30 0 MyriadPro-LightIt Type 1C Custom yes no yes 32 0 MyriadPro-SemiboldIt Type 1C Custom yes no yes 33 0 VUKITP+MTSY Type 1C Custom yes yes yes 84 0 MyriadPro-Regular2 Type 1C WinAnsi yes no yes 694 0 QPSHTR+WarnockPro-It Type 1C WinAnsi yes yes yes 147 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 03:42:35 CEST RepresentationInformation: pmc_32572647.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 11:46:48 CEST Size: 1527082 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 849 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review Children: Item: Title: Abstract Item: Title: The endothelial glycocalyx Children: Item: Title: Composition and structure of the endothelial glycocalyx Item: Title: Physiological function of the endothelial glycocalyx Children: Item: Title: Regulation of vascular permeability and barrier function Item: Title: Mechanosensory function Item: Title: Rheological function Item: Title: Anticoagulation function Item: Title: Protective function against free radicals Item: Title: Physiological role of endogenous albumin Item: Title: Alterations of the endothelial glycocalyx Children: Item: Title: Pathologiesinterventions associated with glycocalyx alterations Children: Item: Title: Ischemia–reperfusion injury Item: Title: Sepsis Item: Title: Hemorrhagic shock Item: Title: Hyperglycemia Item: Title: Other Item: Title: Potential effects of fluid therapy Children: Item: Title: Hypervolemia and type of fluid administered Item: Title: Markers of endothelial damage Children: Item: Title: Box 1. Biomarkers of endothelial damage Item: Title: Role of human albumin in maintaining glycocalyx integrity Children: Item: Title: Pre-clinical studies of the effect of human albumin on the glycocalyx and microcirculation Item: Title: Clinical studies on the effect of human albumin in the glycocalyx and microcirculation Item: Title: Conclusions and expert opinion Children: Item: Title: Monitoring the microcirculation and endothelial damage Item: Title: Further research Item: Title: Acknowledgements Item: Title: References Info: Title: Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review Author: Cesar Aldecoa Subject: Annals of Intensive Care, https://doi.org/10.1186/s13613-020-00697-1 Keywords: Endothelial cell,Glycocalyx,Albumin,Microcirculation,Sepsis Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Wed Jun 17 13:27:27 CEST 2020 ModDate: Mon Jun 22 11:28:47 CEST 2020 ID: 0xbaf30335bf604255d83b42d3668fa9a8, 0xa6cb2ea06e4068c6084b73af5be258e9 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 898 ImageHeight: 800 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1961 ImageHeight: 788 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 898 ImageHeight: 461 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1961 ImageHeight: 953 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: MyriadPro-LightIt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-LightIt Flags: Nonsymbolic, Italic FontBBox: -121, -250, 1007, 863 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-SemiboldIt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldIt Flags: Nonsymbolic, Italic FontBBox: -193, -250, 1164, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Light FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Light Flags: Nonsymbolic FontBBox: -49, -250, 1046, 883 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: QPSHTR+WarnockPro-It FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: QPSHTR+WarnockPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -221, -533, 1474, 950 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: VUKITP+MTSY FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: VUKITP+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: WarnockPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WarnockPro-Regular Flags: Serif, Nonsymbolic FontBBox: -177, -533, 1474, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: 2020-06-17T16:27:27+05:30 Springer 2020-06-22T11:28:47+02:00 2020-06-22T11:28:47+02:00 Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) Endothelial cell,Glycocalyx,Albumin,Microcirculation,Sepsis application/pdf https://doi.org/10.1186/s13613-020-00697-1 Springer International Publishing Annals of Intensive Care, https://doi.org/10.1186/s13613-020-00697-1 Endothelial cell Glycocalyx Albumin Microcirculation Sepsis Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review Cesar Aldecoa Juan V. 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