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1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: ISCI101296_proof_v23i7.pdf Children: Item: Title: Immune Cell Associations with Cancer Risk Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Item: Title: Results Destination: flink2 Children: Item: Title: Strategy to Evaluate Immune/Stromal Cell Tissue Contents that Influence Cancer Risk Destination: slink1 Item: Title: Identification of Cancer Risk Variants Linked to Differences in Immune/Stromal Cell Tissue Content Destination: slink2 Item: Title: Identification of Cancer Risk Variants Associated with Immune System Functions in Target Tissue and Primary Tumors Destination: slink3 Item: Title: PRS Associations with Immune/Stromal Cell Tissue Content Highlight Breast Cancer Risk Destination: slink4 Item: Title: SH2B3 Connects Immune Cell Tissue Content with Breast Cancer Risk Destination: slink5 Item: Title: Peripheral Immune Cell Counts Are Associated with Breast Cancer Risk Destination: slink6 Item: Title: Discussion Destination: flink3 Children: Item: Title: Limitations of the Study Destination: slink7 Item: Title: Resource Availability Destination: slink8 Children: Item: Title: Lead Contact Destination: tlink1 Item: Title: Materials Availability Destination: tlink2 Item: Title: Data and Code Availability Destination: tlink3 Item: Title: Methods Destination: flink4 Item: Title: Supplemental Information Destination: falink5 Item: Title: Acknowledgments Destination: acklink1 Item: Title: Author Contributions Destination: flink6 Item: Title: Declaration of Interests Destination: flink7 Item: Title: References Destination: blink1 Item: Title: isci_101296_mmc1.pdf Children: Item: Title: SupplFigLegends Item: Title: Palomero_FigS1 Item: Title: Palomero_FigS2 Item: Title: Palomero_FigS3 Item: Title: Palomero_FigS4 Item: Title: Palomero_FigS5 Item: Title: Palomero_FigS6 Item: Title: Palomero_FigS7 Item: Title: Palomero_FigS8 Item: Title: Palomero_FigS9 Item: Title: Palomero_FigS10 Item: Title: Palomero_FigS11 Item: Title: Palomero_FigS12 Item: Title: Palomero_TransparentMethods-final_iScience Info: Title: Immune Cell Associations with Cancer Risk Author: Luis Palomero Subject: ISCIENCE, 23 (2020) 101296. doi:10.1016/j.isci.2020.101296 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Wed Jul 01 22:57:26 CEST 2020 ModDate: Wed Jul 01 23:01:22 CEST 2020 ID: 0x1e393034a216c02556b03889e071d6d4, 0x023a91b758779b4f97a4b903e7c701e8 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1569 ImageHeight: 1569 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 69 ImageHeight: 68 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: 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Supplement: 0 FontDescriptor: FontName: VZIIXG+Helvetica Flags: Symbolic FontBBox: -951, -481, 1446, 1122 FontFile2: true XMP: application/pdf doi:10.1016/j.isci.2020.101296 Immune Cell Associations with Cancer Risk Luis Palomero Ivan Galván-Femenía Rafael de Cid Roderic Espín Daniel R. Barnes CIMBA Eline Blommaert Miguel Gil-Gil Catalina Falo Agostina Stradella Dan Ouchi Albert Roso-Llorach Concepció Violan María Peña-Chilet Joaquín Dopazo Ana Isabel Extremera Mar García-Valero Carmen Herranz Francesca Mateo Elisabetta Mereu Jonathan Beesley Georgia Chenevix-Trench Cecilia Roux Tak Mak Joan Brunet Razq Hakem Chiara Gorrini Antonis C. Antoniou Conxi Lázaro Miquel Angel Pujana Immunology Cancer Systems Biology Cancer ISCIENCE, 23 (2020) 101296. doi:10.1016/j.isci.2020.101296 Elsevier Inc. journal ISCIENCE © 2020 The Author(s). 2589-0042 23 7 24 July 2020 2020-07-24 101296 101296 10.1016/j.isci.2020.101296 https://doi.org/10.1016/j.isci.2020.101296 2010-04-23 true 10.1016/j.isci.2020.101296 elsevier.com sciencedirect.com VoR 6.5 10.1016/j.isci.2020.101296 noindex 28 true 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2020-07-02T01:57:26+05:30 2020-07-02T02:01:22+05:30 2020-07-02T02:01:22+05:30 True Acrobat Distiller 8.1.0 (Windows) uuid:cd4c32f6-ebc7-4a73-a92a-19e6e9db14e8 uuid:fef374cb-9292-4ea8-b907-3c1830abfd3d http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 455, 475, 527, 481 Annotation: Subtype: Link Rect: 455, 457, 521, 463 Annotation: Subtype: Link Rect: 455, 448, 529, 454 Annotation: Subtype: Link Rect: 455, 68, 520, 74 Annotation: 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191, 230 Annotation: Subtype: Link Rect: 57, 215, 207, 222 Annotation: Subtype: Link Rect: 57, 197, 197, 204 Annotation: Subtype: Link Rect: 57, 189, 185, 196 Annotation: Subtype: Link Rect: 57, 181, 204, 188 Annotation: Subtype: Link Rect: 57, 173, 208, 180 Annotation: Subtype: Link Rect: 57, 165, 206, 172 Annotation: Subtype: Link Rect: 57, 157, 126, 164 Annotation: Subtype: Link Rect: 57, 138, 195, 145 Annotation: Subtype: Link Rect: 57, 131, 197, 137 Annotation: Subtype: Link Rect: 57, 123, 208, 129 Annotation: Subtype: Link Rect: 57, 115, 186, 122 Annotation: Subtype: Link Rect: 57, 107, 204, 114 Annotation: Subtype: Link Rect: 57, 99, 205, 106 Annotation: Subtype: Link Rect: 57, 80, 202, 87 Annotation: Subtype: Link Rect: 57, 72, 204, 79 Annotation: Subtype: Link Rect: 57, 64, 175, 71 Annotation: Subtype: Link Rect: 57, 56, 204, 63 Annotation: Subtype: Link Rect: 57, 48, 119, 55 Annotation: Subtype: Link Rect: 226, 672, 376, 679 Annotation: Subtype: Link Rect: 226, 664, 347, 671 Annotation: Subtype: Link Rect: 226, 656, 376, 663 Annotation: Subtype: Link Rect: 226, 648, 360, 655 Annotation: Subtype: Link Rect: 226, 640, 373, 647 Annotation: Subtype: Link Rect: 226, 632, 302, 639 Annotation: Subtype: Link Rect: 226, 614, 373, 621 Annotation: Subtype: Link Rect: 226, 606, 356, 613 Annotation: Subtype: Link Rect: 226, 598, 368, 605 Annotation: Subtype: Link Rect: 226, 590, 349, 597 Annotation: Subtype: Link Rect: 226, 572, 367, 579 Annotation: Subtype: Link Rect: 226, 564, 376, 571 Annotation: Subtype: Link Rect: 226, 556, 368, 563 Annotation: Subtype: Link Rect: 226, 548, 376, 555 Annotation: Subtype: Link Rect: 226, 540, 370, 547 Annotation: Subtype: Link Rect: 226, 532, 242, 539 Annotation: Subtype: Link Rect: 226, 514, 376, 521 Annotation: Subtype: Link Rect: 226, 506, 341, 513 Annotation: Subtype: Link Rect: 226, 498, 367, 505 Annotation: Subtype: Link Rect: 226, 490, 351, 497 Annotation: Subtype: Link Rect: 226, 482, 368, 489 Annotation: Subtype: Link Rect: 226, 474, 372, 481 Annotation: Subtype: Link Rect: 226, 466, 276, 473 Annotation: Subtype: Link Rect: 226, 447, 370, 454 Annotation: Subtype: Link Rect: 226, 440, 374, 447 Annotation: Subtype: Link Rect: 226, 432, 376, 439 Annotation: Subtype: Link Rect: 226, 424, 354, 431 Annotation: Subtype: Link Rect: 226, 416, 371, 423 Annotation: Subtype: Link Rect: 226, 408, 325, 415 Annotation: Subtype: Link Rect: 226, 389, 375, 396 Annotation: Subtype: Link Rect: 226, 381, 376, 388 Annotation: Subtype: Link Rect: 226, 373, 364, 380 Annotation: Subtype: Link Rect: 226, 365, 376, 372 Annotation: Subtype: Link Rect: 226, 357, 374, 364 Annotation: Subtype: Link Rect: 226, 350, 372, 356 Annotation: Subtype: Link Rect: 226, 342, 315, 349 Annotation: Subtype: Link Rect: 226, 323, 365, 330 Annotation: Subtype: Link Rect: 226, 315, 372, 322 Annotation: Subtype: Link Rect: 226, 307, 371, 314 Annotation: Subtype: Link Rect: 226, 299, 370, 306 Annotation: Subtype: Link Rect: 226, 291, 303, 298 Annotation: Subtype: Link Rect: 226, 273, 376, 280 Annotation: Subtype: Link Rect: 226, 265, 376, 272 Annotation: Subtype: Link Rect: 226, 257, 366, 264 Annotation: Subtype: Link Rect: 226, 249, 374, 256 Annotation: Subtype: Link Rect: 226, 241, 284, 248 Annotation: Subtype: Link Rect: 226, 223, 376, 230 Annotation: Subtype: Link Rect: 226, 215, 376, 222 Annotation: Subtype: Link Rect: 226, 207, 373, 214 Annotation: Subtype: Link Rect: 226, 199, 354, 206 Annotation: Subtype: Link Rect: 226, 181, 368, 188 Annotation: Subtype: Link Rect: 226, 173, 370, 180 Annotation: Subtype: Link Rect: 226, 165, 376, 172 Annotation: Subtype: Link Rect: 226, 157, 365, 164 Annotation: Subtype: Link Rect: 226, 149, 349, 156 Annotation: Subtype: Link Rect: 226, 141, 350, 148 Annotation: Subtype: Link Rect: 226, 123, 376, 129 Annotation: Subtype: Link Rect: 226, 115, 343, 122 Annotation: Subtype: Link Rect: 226, 107, 362, 114 Annotation: Subtype: Link Rect: 226, 99, 376, 106 Annotation: Subtype: Link Rect: 226, 91, 367, 98 Annotation: Subtype: Link Rect: 226, 83, 260, 90 Annotation: Subtype: Link Rect: 226, 64, 354, 71 Annotation: Subtype: Link Rect: 226, 56, 367, 63 Annotation: Subtype: Link Rect: 226, 48, 305, 55 Annotation: Subtype: Link Rect: 394, 672, 534, 679 Annotation: Subtype: Link Rect: 394, 664, 523, 671 Annotation: Subtype: Link Rect: 394, 656, 544, 663 Annotation: Subtype: Link Rect: 394, 648, 410, 655 Annotation: Subtype: Link Rect: 394, 632, 544, 638 Annotation: Subtype: Link Rect: 394, 624, 544, 630 Annotation: Subtype: Link Rect: 394, 616, 544, 622 Annotation: Subtype: Link Rect: 394, 608, 542, 615 Annotation: Subtype: Link Rect: 394, 600, 454, 607 Annotation: Subtype: Link Rect: 394, 583, 544, 590 Annotation: Subtype: Link Rect: 394, 575, 501, 582 Annotation: Subtype: Link Rect: 394, 567, 534, 574 Annotation: Subtype: Link Rect: 394, 559, 414, 566 Annotation: Subtype: Link Rect: 394, 542, 544, 549 Annotation: Subtype: Link Rect: 394, 534, 544, 541 Annotation: Subtype: Link Rect: 394, 526, 529, 533 Annotation: Subtype: Link Rect: 394, 518, 544, 525 Annotation: Subtype: Link Rect: 394, 510, 479, 517 Annotation: Subtype: Link Rect: 394, 494, 544, 501 Annotation: Subtype: Link Rect: 394, 486, 535, 493 Annotation: Subtype: Link Rect: 394, 478, 538, 485 Annotation: Subtype: Link Rect: 394, 470, 544, 477 Annotation: Subtype: Link Rect: 394, 462, 544, 469 Annotation: Subtype: Link Rect: 394, 454, 421, 461 Annotation: Subtype: Link Rect: 394, 437, 532, 444 Annotation: Subtype: Link Rect: 394, 429, 535, 436 Annotation: Subtype: Link Rect: 394, 412, 541, 419 Annotation: Subtype: Link Rect: 394, 405, 538, 411 Annotation: Subtype: Link Rect: 394, 397, 542, 403 Annotation: Subtype: Link Rect: 394, 389, 540, 396 Annotation: Subtype: Link Rect: 394, 381, 434, 388 Annotation: Subtype: Link Rect: 394, 364, 540, 371 Annotation: Subtype: Link Rect: 394, 356, 520, 363 Annotation: Subtype: Link Rect: 394, 348, 524, 355 Annotation: Subtype: Link Rect: 394, 340, 421, 347 Annotation: Subtype: Link Rect: 394, 323, 544, 330 Annotation: Subtype: Link Rect: 394, 315, 538, 322 Annotation: Subtype: Link Rect: 394, 307, 543, 314 Annotation: Subtype: Link Rect: 394, 299, 520, 306 Annotation: Subtype: Link Rect: 394, 291, 534, 298 Annotation: Subtype: Link Rect: 394, 283, 496, 290 Annotation: Subtype: Link Rect: 394, 267, 525, 274 Annotation: Subtype: Link Rect: 394, 259, 534, 266 Annotation: Subtype: Link Rect: 394, 251, 538, 258 Annotation: Subtype: Link Rect: 394, 243, 544, 250 Annotation: Subtype: Link Rect: 394, 235, 544, 242 Annotation: Subtype: Link Rect: 394, 218, 541, 225 Annotation: Subtype: Link Rect: 394, 210, 535, 217 Annotation: Subtype: Link Rect: 394, 202, 532, 209 Annotation: Subtype: Link Rect: 394, 194, 544, 201 Annotation: Subtype: Link Rect: 394, 186, 535, 193 Annotation: Subtype: Link Rect: 394, 178, 450, 185 Annotation: Subtype: Link Rect: 394, 162, 535, 169 Annotation: Subtype: Link Rect: 394, 154, 518, 161 Annotation: Subtype: Link Rect: 394, 146, 535, 153 Annotation: Subtype: Link Rect: 394, 138, 543, 145 Annotation: Subtype: Link Rect: 394, 130, 476, 137 Annotation: Subtype: Link Rect: 394, 113, 540, 120 Annotation: Subtype: Link Rect: 394, 105, 527, 112 Annotation: Subtype: Link Rect: 394, 97, 543, 104 Annotation: Subtype: Link Rect: 394, 80, 544, 87 Annotation: Subtype: Link Rect: 394, 72, 544, 79 Annotation: Subtype: Link Rect: 394, 64, 529, 71 Annotation: Subtype: Link Rect: 394, 56, 544, 63 Annotation: Subtype: Link Rect: 394, 48, 467, 55 Page: Label: 14 Page: Label: 15 Page: Label: 16 Page: Label: 17 Page: Label: 18 Page: Label: 19 Thumb: true Page: Label: 20 Thumb: true Page: Label: 21 Thumb: true Page: Label: 22 Thumb: true Page: Label: 23 Thumb: true Page: Label: 24 Thumb: true Page: Label: 25 Thumb: true Page: Label: 26 Thumb: true Page: Label: 27 Thumb: true Page: Label: 28 Thumb: true Page: Label: 29 Thumb: true Page: Label: 30 Thumb: true Page: Label: 31 Page: Label: 32 Page: Label: 33 Page: Label: 34 Page: Label: 35 Page: Label: 36 Page: Label: 37 Page: Label: 38 Page: Label: 39 Page: Label: 40 Page: Label: 41 Checksum: 713049e2 Type: CRC32 Checksum: 83620b9df2ac8f74c99ede35731ac07f Type: MD5 Checksum: eab4a7f0d42cae19ba20a0568ca55e9c6dc68e68 Type: SHA-1 Checksum: 6a02ceb0be495d1c6b37e531409325facf18bc351201b15e2905551445b7d5f7 Type: SHA-256