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Fuggle Creator: Springer CreationDate: Tue Jul 28 12:18:19 2020 CEST ModDate: Thu Oct 1 17:18:01 2020 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 990364 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-SemiCn Type 1C Custom yes no yes 917 0 MyriadPro-Semibold Type 1C Custom yes no yes 918 0 MyriadPro-SemiboldSemiCn Type 1C Custom yes no yes 919 0 MyriadPro-Bold Type 1C Custom yes no yes 920 0 JGFGJB+STIX-Regular Type 1C Custom yes yes yes 921 0 CMHAFY+Wingdings-Regular Type 1C WinAnsi yes yes yes 942 0 MURPBG+MyriadPro-SemiCn2 Type 1C WinAnsi yes yes yes 964 0 STIX-Italic Type 1C WinAnsi yes no yes 577 0 MyriadPro-SemiCn3 Type 1C WinAnsi yes no yes 597 0 MyriadPro-BoldSemiCn Type 1C WinAnsi yes no yes 710 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-05-26 02:40:51 CEST RepresentationInformation: pmc_32725307.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-11-02 03:38:47 CET Size: 990364 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1000 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs Children: Item: Title: Abstract Item: Title: 1 Introduction Item: Title: 2 Calcium Supplementation Item: Title: 3 Vitamin D Item: Title: 4 Menopausal Hormonal Therapy Item: Title: 5 Tibolone Item: Title: 6 Selective Estrogen Receptor Modulators Item: Title: 7 Bisphosphonates Item: Title: 8 Denosumab Item: Title: 9 Parathyroid Hormone Analogues Item: Title: 10 Romosozumab Item: Title: 11 Conclusions Item: Title: References Info: Title: Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs Author: N. R. Fuggle Subject: Drugs, https://doi.org/10.1007/s40265-020-01364-2 Creator: Springer CreationDate: Tue Jul 28 12:48:19 CEST 2020 ModDate: Thu Oct 01 17:48:01 CEST 2020 ID: 0x8637cfb5815b604cb14bb64cd07443c2, 0x7dbdc97bb6b5494383ad43f65e9eae00 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 969 ImageHeight: 882 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1418 ImageHeight: 1112 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: STIX-Italic FirstChar: 0 LastChar: 255 FontDescriptor: FontName: STIX-Italic Flags: Serif, Nonsymbolic, Italic FontBBox: -970, -305, 1429, 1023 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-SemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiCn Flags: Nonsymbolic FontBBox: -128, -250, 1059, 876 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-BoldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-BoldSemiCn Flags: Nonsymbolic FontBBox: -159, -250, 1161, 980 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-SemiboldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldSemiCn Flags: Nonsymbolic FontBBox: -156, -250, 1115, 963 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: JGFGJB+STIX-Regular FontSubset: true FirstChar: 20 LastChar: 252 FontDescriptor: FontName: JGFGJB+STIX-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: CMHAFY+Wingdings-Regular FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: CMHAFY+Wingdings-Regular Flags: Nonsymbolic FontBBox: 0, -103, 1359, 439 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true XMP: 2020-07-28T15:48:19+05:30 Springer 2020-10-01T20:48:01+05:30 2020-10-01T20:48:01+05:30 application/pdf https://doi.org/10.1007/s40265-020-01364-2 Springer International Publishing Drugs, https://doi.org/10.1007/s40265-020-01364-2 Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs N. R. Fuggle C. Cooper N. C. Harvey N. Al-Daghri M.-L. Brandi O. Bruyere A. Cano E. M. Dennison A. Diez-Perez J.-M. Kaufman S. Palacios D. Prieto-Alhambra S. Rozenberg T. Thomas F. Tremollieres R. Rizzoli J. A. Kanis J. Y. 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