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Turner Subject: Background: There has been increased concern about the suitability of CO2 as a method for euthanasia of laboratory mice and rats, including the potential discomfort, pain or distress that animals may experience prior to loss of consciousness; time to loss of consciousness; best methods for use of CO2; and the availability of better alternatives. 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Turner Background: There has been increased concern about the suitability of CO2 as a method for euthanasia of laboratory mice and rats, including the potential discomfort, pain or distress that animals may experience prior to loss of consciousness; time to loss of consciousness; best methods for use of CO2; and the availability of better alternatives. 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685, 95, 697 Destination: External Annotation: Subtype: Link Rect: 47, 582, 58, 594 Destination: External Annotation: Subtype: Link Rect: 260, 479, 271, 491 Destination: External Annotation: Subtype: Link Rect: 275, 479, 286, 491 Destination: External Annotation: Subtype: Link Rect: 43, 468, 54, 479 Destination: External Annotation: Subtype: Link Rect: 59, 468, 70, 479 Destination: External Annotation: Subtype: Link Rect: 107, 261, 118, 273 Destination: External Annotation: Subtype: Link Rect: 253, 158, 264, 170 Destination: External Annotation: Subtype: Link Rect: 211, 135, 223, 147 Destination: External Annotation: Subtype: Link Rect: 55, 78, 85, 87 Destination: External Annotation: Subtype: Link Rect: 376, 525, 387, 536 Destination: External Annotation: Subtype: Link Rect: 390, 525, 401, 536 Destination: External Annotation: Subtype: Link Rect: 405, 525, 416, 536 Destination: External Annotation: Subtype: Link Rect: 364, 514, 375, 525 Destination: External Annotation: Subtype: Link 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Annotation: Subtype: Link Rect: 420, 284, 431, 296 Destination: External Annotation: Subtype: Link Rect: 435, 284, 446, 296 Destination: External Annotation: Subtype: Link Rect: 451, 284, 462, 296 Destination: External Annotation: Subtype: Link Rect: 466, 284, 477, 296 Destination: External Annotation: Subtype: Link Rect: 307, 250, 318, 261 Destination: External Annotation: Subtype: Link Rect: 320, 250, 332, 261 Destination: External Annotation: Subtype: Link Rect: 334, 250, 345, 261 Destination: External Annotation: Subtype: Link Rect: 348, 250, 359, 261 Destination: External Annotation: Subtype: Link Rect: 361, 250, 372, 261 Destination: External Annotation: Subtype: Link Rect: 475, 227, 486, 239 Destination: External Annotation: Subtype: Link Rect: 408, 170, 419, 181 Destination: External Annotation: Subtype: Link Rect: 355, 78, 366, 90 Destination: External Annotation: Subtype: Link Rect: 371, 78, 382, 90 Destination: External Annotation: Subtype: Link Rect: 387, 78, 398, 90 Destination: External Annotation: Subtype: Link Rect: 403, 78, 414, 90 Destination: External Annotation: Subtype: Link Rect: 419, 78, 430, 90 Destination: External Annotation: Subtype: Link Rect: 435, 78, 446, 90 Destination: External Annotation: Subtype: Link Rect: 449, 78, 460, 90 Destination: External Annotation: Subtype: Link Rect: 465, 78, 476, 90 Destination: External Annotation: Subtype: Link Rect: 43, 29, 135, 38 Annotation: Subtype: Link Rect: 139, 29, 199, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 15 Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 140, 640, 151, 651 Destination: External Annotation: Subtype: Link Rect: 248, 605, 259, 617 Destination: External Annotation: Subtype: Link Rect: 148, 571, 159, 582 Destination: External Annotation: Subtype: Link Rect: 96, 536, 107, 548 Destination: External Annotation: Subtype: Link Rect: 149, 502, 160, 514 Destination: External Annotation: Subtype: Link Rect: 165, 502, 176, 514 Destination: External Annotation: Subtype: Link Rect: 181, 502, 193, 514 Destination: External Annotation: Subtype: Link Rect: 133, 491, 144, 502 Destination: External Annotation: Subtype: Link Rect: 47, 342, 58, 353 Destination: External Annotation: Subtype: Link Rect: 62, 342, 73, 353 Destination: External Annotation: Subtype: Link Rect: 78, 342, 89, 353 Destination: External Annotation: Subtype: Link Rect: 94, 342, 105, 353 Destination: External Annotation: Subtype: Link Rect: 189, 330, 200, 342 Destination: External Annotation: Subtype: Link Rect: 84, 296, 95, 307 Destination: External Annotation: Subtype: Link Rect: 255, 238, 285, 247 Destination: External Annotation: Subtype: Link Rect: 251, 193, 262, 204 Destination: External Annotation: Subtype: Link Rect: 47, 147, 58, 158 Destination: External Annotation: Subtype: Link Rect: 184, 113, 195, 124 Destination: External Annotation: Subtype: Link Rect: 129, 90, 140, 101 Destination: External Annotation: Subtype: Link Rect: 442, 708, 453, 720 Destination: External Annotation: Subtype: Link Rect: 307, 674, 318, 685 Destination: External Annotation: Subtype: Link Rect: 397, 546, 404, 558 Destination: External Annotation: Subtype: Link Rect: 408, 546, 419, 558 Destination: External Annotation: Subtype: Link Rect: 43, 29, 135, 38 Annotation: Subtype: Link Rect: 139, 29, 199, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 16 Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 160, 525, 171, 536 Destination: External Annotation: Subtype: Link Rect: 173, 525, 184, 536 Destination: External Annotation: Subtype: Link Rect: 98, 491, 109, 502 Destination: External Annotation: Subtype: Link Rect: 115, 491, 126, 502 Destination: External Annotation: Subtype: Link Rect: 206, 330, 217, 342 Destination: External Annotation: Subtype: Link Rect: 159, 250, 170, 261 Destination: External Annotation: Subtype: Link Rect: 341, 674, 352, 685 Destination: External Annotation: Subtype: Link Rect: 354, 674, 365, 685 Destination: External Annotation: Subtype: Link Rect: 367, 674, 378, 685 Destination: External Annotation: Subtype: Link Rect: 521, 617, 532, 628 Destination: External Annotation: Subtype: Link Rect: 330, 430, 429, 441 Destination: External Annotation: Subtype: Link Rect: 552, 114, 303, 138 Annotation: Subtype: Link Rect: 43, 29, 135, 38 Annotation: Subtype: Link Rect: 139, 29, 199, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Page: Label: 17 Sequence: 17 Annotations: Annotation: Subtype: Link Rect: 250, 678, 291, 687 Annotation: Subtype: Link Rect: 57, 669, 204, 678 Annotation: Subtype: Link Rect: 122, 623, 187, 630 Annotation: Subtype: Link Rect: 77, 602, 138, 612 Annotation: Subtype: Link Rect: 90, 555, 175, 564 Annotation: Subtype: Link Rect: 81, 538, 193, 545 Annotation: Subtype: Link Rect: 202, 509, 288, 517 Annotation: Subtype: Link Rect: 216, 481, 278, 488 Annotation: Subtype: Link Rect: 90, 443, 152, 450 Annotation: Subtype: Link Rect: 207, 413, 285, 422 Annotation: Subtype: Link Rect: 195, 366, 290, 375 Annotation: Subtype: Link Rect: 234, 337, 291, 347 Annotation: Subtype: Link Rect: 57, 329, 236, 337 Annotation: Subtype: Link Rect: 143, 292, 221, 299 Annotation: Subtype: Link Rect: 155, 263, 248, 271 Annotation: Subtype: Link Rect: 153, 139, 251, 148 Annotation: Subtype: Link Rect: 338, 687, 435, 697 Annotation: Subtype: Link Rect: 345, 661, 430, 668 Annotation: Subtype: Link Rect: 345, 631, 442, 640 Annotation: Subtype: Link Rect: 338, 593, 435, 602 Annotation: Subtype: Link Rect: 386, 566, 446, 574 Annotation: Subtype: Link Rect: 360, 527, 453, 536 Annotation: Subtype: Link Rect: 341, 470, 438, 479 Annotation: Subtype: Link Rect: 403, 405, 488, 413 Annotation: Subtype: Link Rect: 371, 366, 464, 375 Annotation: Subtype: Link Rect: 361, 329, 453, 337 Annotation: Subtype: Link Rect: 358, 273, 450, 280 Annotation: Subtype: Link Rect: 469, 206, 531, 214 Annotation: Subtype: Link Rect: 368, 148, 466, 157 Annotation: Subtype: Link Rect: 372, 120, 469, 129 Annotation: Subtype: Link Rect: 436, 101, 533, 110 Annotation: Subtype: Link Rect: 368, 72, 466, 82 Annotation: Subtype: Link Rect: 43, 28, 135, 37 Annotation: Subtype: Link Rect: 139, 28, 199, 36 Annotation: Subtype: Link Rect: 449, 28, 551, 37 Page: Label: 18 Sequence: 18 Annotations: Annotation: Subtype: Link Rect: 81, 687, 178, 697 Annotation: Subtype: Link Rect: 81, 632, 173, 640 Annotation: Subtype: Link Rect: 183, 613, 254, 621 Annotation: Subtype: Link Rect: 77, 576, 163, 583 Annotation: Subtype: Link Rect: 189, 498, 291, 508 Annotation: Subtype: Link Rect: 57, 489, 171, 498 Annotation: Subtype: Link Rect: 111, 451, 202, 460 Annotation: Subtype: Link Rect: 111, 422, 204, 432 Annotation: Subtype: Link Rect: 189, 394, 280, 403 Annotation: Subtype: Link Rect: 440, 687, 551, 697 Annotation: Subtype: Link Rect: 317, 680, 365, 687 Annotation: Subtype: Link Rect: 371, 593, 464, 602 Annotation: Subtype: Link Rect: 354, 557, 417, 564 Annotation: Subtype: Link Rect: 318, 443, 344, 450 Annotation: Subtype: Link Rect: 347, 443, 379, 450 Annotation: Subtype: Link Rect: 382, 443, 418, 450 Annotation: Subtype: Link Rect: 421, 443, 444, 450 Annotation: Subtype: Link Rect: 447, 442, 477, 450 Annotation: Subtype: Link Rect: 43, 29, 135, 38 Annotation: Subtype: Link Rect: 139, 29, 199, 37 Annotation: Subtype: Link Rect: 449, 29, 551, 38 Checksum: 8ddf43fa Type: CRC32 Checksum: 52f0c57e337364614aa82b9a71bbaebd Type: MD5 Checksum: 9d304a3dcc6782f861e298480555b83a6c655bcb Type: SHA-1